Non-Invasive Hemodynamic Monitoring in Hospitalized Heart Failure

June 26, 2026

Conditions: Heart Failure; Heart Failure Hospitalization; Heart Failure (HF)
Sponsors: Acorai AB
Recruiting

Personalized Blood Transfusion Protocol for Cardiac Patients

June 26, 2026

Conditions: Cardiac Surgery; Blood Transfusion; Anemia; Cardiopulmonary Bypass
Interventions: Other: Demand-Informed Transfusion Decision Rule
Sponsors: Yan Mia Min; Stanford University
Not yet recruiting

Comprehensive Perioperative Program Based on Prehabilitation, Nutritional Intervention and Psychological Support for Patients With Locally Advanced Operable Oesophagogastric Cancer

June 26, 2026

Conditions: Locally Advanced Esophageal Cancer; Gastroesophageal Junction Cancer; Gastric Cancer
Interventions: Diagnostic Test: Cardiorespiratory fitness (FsPS); Other: Exercises you can do on your own at home; Other: Enhanced Recovery After Surgery ERAS; Other: Nutritional support; Other: Psychological support; Other: Quality of life; Diagnostic Test: Laboratory tests
Sponsors: Masaryk Memorial Cancer Institute
Recruiting

Effects of an Osteopathic Manual Therapy Protocol on Heart Rate Variability, Stress, and Anxiety in Young Adults

June 26, 2026

Conditions: Stress; Anxiety
Interventions: Other: Fourth Ventricle Technique; Other: Suboccipital Decompression; Other: Diaphragm Myofascial Release Technique; Other: Sacral Rock; Other: Sham Cranial Listening
Sponsors: Escola Superior de Tecnologia da Saúde do Porto
Not yet recruiting

University of Georgia Mind Your Heart Pilot Study

June 26, 2026

Conditions: Hypertension (HTN); Obesity & Overweight
Interventions: Behavioral: Mind Your Heart; Behavioral: DASH Diet Education
Sponsors: University of Georgia
Completed

Phase II Trial of SFRT Plus Chemo-immunotherapy for LA-NSCLC With Suboptimal Neoadjuvant Response

June 26, 2026

Conditions: Locally Advanced Non-small Cell Lung Cancer (NSCLC); Thoracic Radiotherapy; Immune Checkpoint Inhibitors; Neoadjuvant Chemoimmunotherapy
Interventions: Radiation: lattice radiation therapy
Sponsors: Tianjin Medical University Cancer Institute and Hospital
Not yet recruiting

PregnAncy-Related Aortic DISsEction in China

June 26, 2026

Conditions: Pregnancy Complication; Aortic Dissection; Marfan Syndrome; Loeys-Dietz Syndrome; Vascular Ehlers-Danlos Syndrome; Maternal and Neonatal Outcomes
Interventions: Other: Intervention strategies including medication or surgery
Sponsors: DeltaHealth Hospital · Shanghai; The Second Affiliated Hospital of Hainan Medical University; Beijing Anzhen Hospital; West China Hospital; Xiangya Hospital of Central South University; Second Xiangya Hospital of Central South University; Sichuan Provincial People's Hospital; Yantai Yuhuangding Hospital; First Hospital of China Medical University; First Affiliated Hospital Xi'an Jiaotong University; Qinghai Red Cross Hospital; Shanxi Bethune Hospital; Shandong Provincial Hospital; Shengjing Hospital; Zhejiang Provincial People's Hospital; Ningbo Medical Center Lihuili Hospital; Central China Fuwai Hospital of Zhengzhou University; Xiamen Cardiovascular Hospital, Xiamen University; The Central Hospital of Linfen; Shenzhen Sun Yat-sen Cardiovascular Hospital; The Affiliated Hospital Of Guizhou Medical University; The University of Hong Kong-Shenzhen Hospital; Hebei Medical University Fourth Hospital; Second Affiliated Hospital of Nanchang University; Southwest Hospital, China; Gulou Hospital Affiliated to Medical College of Nanjing University; The Second Hospital of Shandong University; First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital of Gannan Medical University; The First Affiliated Hospital of Zhengzhou University; Lanzhou University First Hospital; Peking Union Medical College Hospital; First Affiliated Hospital of Harbin Medical University; The First Hospital of Jilin University; The Fourth Affiliated Hospital of Zhejiang University School of Medicine; RenJi Hospital; Peking University People's Hospital; The First Affiliated Hospital of Guangzhou Medical University; Henan Provincial Chest Hospital; First Affiliated Hospital of Wenzhou Medical University; Shanghai Zhongshan Hospital; Qilu Hospital of Shandong University; The First Affiliated Hospital of Bengbu Medical University; Wannan Medical College Yijishan Hospital; Anhui Provincial Hospital; Shanxi Yuncheng Central Hospital; Liuzhou Workers' Hospital; The Third People's Hospital of Chengdu; Suining Central Hospital; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Wuhan TongJi Hospital; Renmin Hospital of Wuhan University; The General Hospital of Southern Theater Command; Xijing Hospital，FMMU; Zunyi Medical College; The Affiliated Hospital of Qingdao University; Shanghai Chest Hospital of Shanghai Jiao Tong University; The First Affiliated Hospital of Anhui Medical University; The People's Hospital of Gaozhou; The Second Hospital of Nanjing Medical University; Nanjing First Hospital, Nanjing Medical University; General Hospital of Ningxia Medical University; Guangdong Provincial People's Hospital; Yan'an Affiliated Hospital of Kunming Medical University; Second Affiliated Hospital of Zhengzhou University; Henan Provincial People's Hospital; Wuhan Asia Heart Hospital; Changhai Hospital; Taihe Hospital affiliated to Hubei University of Medicine; Zhongnan Hospital; Luoyang Central Hospital; People's Hospital of Xinjiang Uygur Autonomous Region; Qingdao Municipal Hospital; The First Affiliated Hospital of Nanchang University; Hainan General Hospital; The First Hospital of Hebei Medical University; Gansu Provincial Hospital; The First Affiliated Hospital of Shanxi Medical University; First Affiliated Hospital of Guangxi Medical University; First Affiliated Hospital of Ningbo University; Fujian Medical University Union Hospital; Huai'an First People's Hospital; Chinese University of Hong Kong; Yichang Central People's Hospital; Zhongshan People's Hospital, Guangdong, China; Shiyan City Renmin Hospital; The First Affiliated Hospital of Dalian Medical University
Enrolling by invitation

Lifestyle Advice in CVD

June 26, 2026

Conditions: Cardio Vascular Disease; Dietary Change; Dietary Behaviors; Diet Habits; Experience; Ethnicity
Interventions: Behavioral: Experience of healthcare
Sponsors: University of Nottingham
Not yet recruiting

Inspiratory Muscle Training for People With Heart Failure

June 26, 2026

Conditions: Heart Failure
Interventions: Other: Inspiratory muscle training with Tapered Resistive Load; Other: Inspiratory muscle training with threshold load; Other: Concurrent Exercise Training
Sponsors: Universidad Nacional Andres Bello
Not yet recruiting

Multimodal Physiotherapy Intervention for People With Migraine

June 26, 2026

Conditions: Migraine
Interventions: Other: Multimodal Treatment Program; Other: Usual Care
Sponsors: Hochschule Osnabruck
Recruiting

Cerebral Autoregulation and Delirium Study

June 26, 2026

Conditions: Delirium - Postoperative; Cardiac Surgery
Interventions: Device: Mespere NeuroOs (Mespere Life Sciences) monitor
Sponsors: University Health Network, Toronto
Not yet recruiting

A Clinical Study to Compare BupiZenge With Lidocaine for Pain Due to Oral Mucositis in Patients With Head and Neck Cancer.

June 26, 2026

Conditions: Head & Neck Cancer; Oral Mucositis
Interventions: Drug: BupiZenge 25 mg; Drug: Lidocaine viscous 2%
Sponsors: OncoZenge AB; LINK Medical Research AB
Not yet recruiting

A Phase III Study of the Efficacy and Safety of Olokizumab in Patients With Polymyalgia Rheumatica

June 26, 2026

Conditions: Polymyalgia Rheumatica
Interventions: Biological: Olokizumab; Drug: Placebo
Sponsors: R-Pharm International, LLC
Active, not recruiting

Anchord Mitral Chordal Repair System - FIH

June 26, 2026

Conditions: Mitral Regurgitation
Interventions: Device: Anchord device implantation
Sponsors: Lifecord Otd
Not yet recruiting

Endothelin Role In COronary Microcirculation

June 26, 2026

Conditions: Coronary Microvascular Dysfunction (CMD); Angina Pectoris With Normal Coronary Arteriogram; Microvascular Angina
Interventions: Diagnostic Test: Cardiac MRI; Procedure: Invasive Coronary Angiogram; Drug: Endothelin Receptor Antagonist
Sponsors: Liverpool University Hospitals NHS Foundation Trust
Active, not recruiting

Effect of NOTCH2NLC Gene Variations on NIID Clinical Features

June 26, 2026

Conditions: Neuronal Intranuclear Inclusion Disease (NIID)
Interventions: Other: No Intervention: Observational Cohort
Sponsors: Sichuan Academy of Medical Sciences
Recruiting

A Study to Learn About Heart-Related Risks in Elderly Men With Advanced Prostate Cancer Treated With Enzalutamide or Darolutamide

June 26, 2026

Conditions: Prostate Cancer
Interventions: Other: No intervention
Sponsors: Bayer
Recruiting

Angiotensin II for Post Cardiac Surgery Vasoplegia (ANGII_V)

June 26, 2026

Conditions: Vasoplegic Shock; Cardiopulmonary Bypass; Vasoplegia
Interventions: Drug: Angiotensin II (Giapreza®)
Sponsors: Methodist Healthcare System of San Antonio
Not yet recruiting

BOdygUardian MOnitoriNg for ReCurrencE of AF

June 26, 2026

Conditions: Atrial Fibrillation (AF)
Interventions: Device: BodyGuardian
Sponsors: Heart Rhythm Clinical and Research Solutions, LLC; Boston Scientific Corporation
Not yet recruiting

Endocarditis Clinical Awareness, Research, and Evaluation in Sweden

June 26, 2026

Conditions: Endocarditis Infective; Endocarditis Acute and Subacute; Endocarditis, Bacterial; Endocarditis Acute
Sponsors: Karolinska Institutet
Active, not recruiting

Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for Bradyarrhythmias

June 26, 2026

Conditions: Bradycardia; Syncope, Vasovagal; Sick Sinus Syndrome; Atrioventricular Block
Interventions: Procedure: Focal Cryoablation; Procedure: Radiofrequency Catheter Ablation
Sponsors: Tomsk National Research Medical Center of the Russian Academy of Sciences
Recruiting

An Ecological Momentary Intervention for Mental Health in Individuals With Ankylosing Spondylitis

June 26, 2026

Conditions: Ankylosing Spondylitis (AS); Mental Health
Interventions: Other: Ecological Momentary Intervention; Other: Attention Control Group
Sponsors: The Hong Kong Polytechnic University
Active, not recruiting

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer

June 26, 2026

Conditions: Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma; Paranasal Sinus Neoplasms; Nasopharyngeal Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Hypopharyngeal Cancer; Carcinoma of Larynx; Oral Squamous Cell Carcinoma; Salivary Gland Cancer; Adenoid Cystic Carcinoma; Prostate Cancer; Metastatic Castration Resistant Prostate Cancer
Interventions: Drug: SX-682; Drug: DTX
Sponsors: National Cancer Institute (NCI)
Not yet recruiting

Pilates for Sedentary Individuals

June 26, 2026

Conditions: Sedentary Behaviors; Core Muscle Weakness
Interventions: Other: Pilates exercise; Other: Walking exercise
Sponsors: Mahidol University
Not yet recruiting

vNOTES vs Laparoscopy: Respiratory Mechanics and Hemodynamics

June 25, 2026

Conditions: Respiratory Mechanics; Hemodynamics
Interventions: Procedure: vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery; Procedure: Laparoscopic Gynecological Surgery
Sponsors: Bursa Yuksek Ihtisas Training and Research Hospital
Not yet recruiting

Correlation Between CT Pulmonary Angiography Metrics and Right Heart Catheterization Parameters in Pre-Capillary Pulmonary Hypertension

June 25, 2026

Conditions: Pulmonary Hypertension; Precapillary Pulmonary Hypertension; Right Heart Catheterisation; CT Angiography
Interventions: Other: right heart catheter
Sponsors: Assiut University
Not yet recruiting

Preoperative Ankle-Brachial Index and Renal Adverse Events After ATAAD Surgery

June 25, 2026

Conditions: Aortic Dissection Type A; Acute Kidney Injury Cardiac Surgery
Interventions: Other: Preoperative Ankle-Brachial Index
Sponsors: Nanjing First Hospital, Nanjing Medical University
Completed

Cardiac Safety Management and Immune Microenvironment Changes After Thoracic Radiotherapy: A Prospective Observational Study

June 25, 2026

Conditions: MACE, Arrhythmia, Pericardial Effusion and Survival
Sponsors: Hebei Medical University Fourth Hospital; National Natural Science Foundation of China
Recruiting

Electrical Impedance Tomography-Guided Identification of the Optimal Lateral Position in Postoperative ARDS

June 25, 2026

Conditions: Acute Respiratory Distress Syndrome (ARDS); Postoperative
Interventions: Behavioral: Positioning Intervention
Sponsors: Ruijin Hospital
Not yet recruiting

Multimodality RV Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 PAH

June 25, 2026

Conditions: Pulmonary Hypertension; Pulmonary Arterial Hypertension; Right Ventricular Function
Sponsors: Istanbul University - Cerrahpasa
Recruiting

Effects of Olfactory Stimuli in Virtual Reality Cue Exposure on Craving and Attentional Bias in Alcohol Use Disorder

June 25, 2026

Conditions: Alcohol Use Disorder
Interventions: Device: VR-CE
Sponsors: Charite University, Berlin, Germany
Not yet recruiting

a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right Shunts

June 25, 2026

Conditions: Sedation and Analgesia
Interventions: Drug: Ketamine + propofol; Drug: Dexmedetomidine + propofol
Sponsors: Ain Shams University
Recruiting

Study of D3L-002 in Subjects With Advanced Solid Tumors

June 25, 2026

Conditions: Advanced Solid Tumor
Interventions: Drug: D3L-002
Sponsors: D3 Bio (Wuxi) Co., Ltd
Not yet recruiting

Efficacy and Safety of Mirabegron Versus Oxybutynin After Posterior Urethral Valve Ablation

June 25, 2026

Conditions: Posterior Urethral Valve
Interventions: Drug: Mirabegron
Sponsors: South Valley University
Completed

The Potential Cardioprotective Effect of Addition of Atorvastatin in Breast Cancer Patients

June 25, 2026

Conditions: Breast Cancer; Doxorubicin Induced Cardiomyopathy
Interventions: Drug: Atorvastatin
Sponsors: Damanhour University
Completed

A Study to Learn How Safe ACT-777991 is and How Well it Works in Adults With Non-segmental Vitiligo

June 25, 2026

Conditions: Non-Segmental Vitiligo
Interventions: Drug: ACT-777991; Drug: Placebo
Sponsors: Idorsia Pharmaceuticals Ltd.
Not yet recruiting

Acute Muscular and Vascular Responses to a Single Session of Exercise With BFR in COPD

June 25, 2026

Conditions: Control Condition; Pulmonary Disease (COPD), Chronic Obstructive; Blood Flow Restriction Training (BFRT)
Interventions: Device: Blood Flow Restriction; Device: Standard exercise session
Sponsors: University Hospital, Grenoble
Not yet recruiting

Reducing Pain During Dental Nerve Block Injections in Children

June 25, 2026

Conditions: Dental Anxiety; Inferior Alveolar Nerve; Pain Management
Interventions: Device: Buzzy Device; Procedure: Counterstimulation; Device: 30-Gauge Needle; Device: 27-Gauge Needle; Drug: Lidocaine hydrochloride 2% with epinephrine 1:100 000
Sponsors: Al-Mustansiriyah University
Completed

Efficacy of Verciguat in TR and RV Failure

June 25, 2026

Conditions: HFrEF; Tricuspid Regurgitation (TR)
Interventions: Drug: Vericiguat
Sponsors: Daejeon St. Mary's hospital; Seoul St. Mary's Hospital; Uijeongbu St. Mary Hospital; Incheon St.Mary's Hospital
Not yet recruiting

Health Ahead Comparative Effectiveness Study

June 25, 2026

Conditions: Health Services Accessibility; Rural Health; Medically Underserved Area; Preventive Health Services; Patient Participation; Health Behavior; Aging; Cardiovascular Diseases; Metabolic Syndrome; Cognitive Dysfunction; Frailty; Activities of Daily Living; Health Related Quality of Life; Health Equity; Telemedecine
Interventions: Behavioral: Interactive Personalized Health Report; Behavioral: Mobile Community-Based Health Screenings; Behavioral: Hybrid Medical Droid and Human Delivered Health Screenings
Sponsors: William Brandenburg, MD
Recruiting

Vasopressor Agents in Pulmonary Hypertension Crisis

June 25, 2026

Conditions: Pulmonary Arterial Hypertension (PAH); Chronic Thromboembolic Pulmonary Hypertension (CTEPH); Hypertension, Pulmonary
Interventions: Drug: Norepinephrine; Drug: Dopamine; Drug: Epinephrine
Sponsors: China National Center for Cardiovascular Diseases
Not yet recruiting

Conventional Fluid Management Versus Plethysmography Variability Index-based Goal-directed Fluid Management in Patients Undergoing Transurethral Resection of the Prostate-a Randomized Controlled Trial

June 25, 2026

Conditions: Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection
Interventions: Other: Conventional Fluid Management; Other: Plethysmography Variability Index (PVI)-Guided Goal-Directed Fluid Management
Sponsors: Cairo University
Active, not recruiting

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

June 25, 2026

Conditions: Diabetes Mellitus, Type 2
Interventions: Drug: UBT251; Drug: UBT251 Placebo; Drug: Semaglutide; Drug: Semaglutide Placebo
Sponsors: Novo Nordisk A/S
Not yet recruiting

Effects of Virtual Reality and Relaxation During Non-Stress Testing

June 25, 2026

Conditions: Maternal Anxiety Level; Non Stress Test (NST); High Risk Pregnancy; Virtual Reality; Progressive Muscle Relaxation Exercise; Physiological Parameters
Interventions: Behavioral: Virtual reality glasses; Behavioral: Progressive muscle relaxation exercises
Sponsors: Istanbul University - Cerrahpasa; Kanuni Sultan Suleyman Training and Research Hospital
Completed

Team-Based Shared Decision-Making Program in Cardiovascular-Kidney-Metabolic Health

June 25, 2026

Conditions: Hypertension (HTN); Diabetes (DM); Hyperlipidaemia; Kidney Disease; Obesity; Cardiovascular-kidney-metabolic (CKM); Overweight
Interventions: Combination Product: Team-based shared decision-making
Sponsors: Johns Hopkins University
Not yet recruiting

Clinical Application of a New Handheld ECG Device

June 25, 2026

Conditions: Cardiac Abnormalities, Variable
Interventions: Device: ECG registration with a handheld ECG device.
Sponsors: HeartEye
Not yet recruiting

The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM)

June 25, 2026

Conditions: Type 2 Diabetes Mellitus (T2DM); Sarcopenia; Insulin Resistance
Interventions: Behavioral: D-STORM Resistance Training Programme; Other: usual care
Sponsors: Universiti Teknologi Mara
Not yet recruiting

Effect of Pre-exercise Inhalation of Molecular Hydrogen on Metabolic Response During Graded Exercise in Healthy Women

June 25, 2026

Conditions: Healthy Adult Females
Interventions: Other: Molecular hydrogen; Other: Placebo
Sponsors: Palacky University
Recruiting

Thrombectomy in Pulmonary Embolism

June 25, 2026

Conditions: Pulmonary Embolism and Thrombosis
Sponsors: University Hospital Plymouth NHS Trust
Recruiting

Efficacy of pHA130 Hemoadsorption on Protein-Bound Uremic Toxins and Quality of Life in Kidney Failure

June 25, 2026

Conditions: ESRD (End-Stage Renal Disease); Maintenance Hemodialysis
Interventions: Device: pHA130 Hemoadsorption Cartridge; Device: High-flux Hemodialyzer
Sponsors: China-Japan Friendship Hospital; Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine
Recruiting

Efficacy and Safety of SP16 in Preventing Acute Kidney Injury in At-risk Subjects With Chronic Kidney Disease Undergoing Elective Cardiac Surgery Using the Heart-lung-machine

June 25, 2026

Conditions: AKI - Acute Kidney Injury
Interventions: Drug: SP16-3M; Drug: Placebo
Sponsors: University of Erlangen-Nürnberg Medical School; Serpin Pharma, LLC
Not yet recruiting

Tele-Pulmonary Rehabilitation For Patients With Chronic Lung Diseases

June 24, 2026

Conditions: COPD (Chronic Obstructive Pulmonary Disease); Rehabilitation; Bronchiectasis Adult; Pulmonary Arterial Hypertension (PAH); Interstitial Lung Disease (ILD)
Interventions: Other: Tele-Rehabilitation
Sponsors: Tel-Aviv Sourasky Medical Center; Barzilai Medical Center; International Respiratory Coalition (IRC)
Not yet recruiting

Tele-Nursing Counseling in Coronary Artery Bypass Graft Surgery

June 24, 2026

Conditions: Coronary Artery Bypass Surgery; Self Care; Telenursing
Interventions: Behavioral: THE EFFECT OF TELENURSING COUNSELING ON SYMPTOM CONTROL AND SELF-CARE ABILITY IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY.
Sponsors: Fenerbahce University
Completed

Pathological Mechanism Study of Aerobic Exercise Regulating Cold Stress-induced Hypertension Via the Thermosensitive Target-mediated Sympathetic Nerve Pathway

June 24, 2026

Conditions: Hypertension
Interventions: Behavioral: Exercise exposure
Sponsors: Wang Jingfeng
Completed

A Study of Metformin to Improve Cardiac Function After LVAD Implantation

June 24, 2026

Conditions: Heart Failure; Left Ventricular Assist Device
Interventions: Drug: Metformin Hydrochloride; Drug: Placebo
Sponsors: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Not yet recruiting

Postoperative Cognitive Function After Different Anesthetic Techniques in Obese Patients

June 24, 2026

Conditions: Obesity (BMI>30); Postoperative Cognitive Function
Interventions: Drug: Sevoflurane (Volatile Anesthetic); Drug: propofol; Drug: Remifentanil
Sponsors: Gaziantep City Hospital
Completed

JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion

June 24, 2026

Conditions: Intracranial Pressure; Critical Care
Interventions: Procedure: Ultrasound assessment
Sponsors: University Hospital, Bordeaux
Not yet recruiting

Ocular Manifestations of Granulomatosis With Polyangiitis.

June 24, 2026

Conditions: GPA; Vasculitis; Microscopic Polyangiitis (MPA); Churg-Strauss Syndrome (CSS)
Interventions: Diagnostic Test: Optical coherence tomography angiography
Sponsors: Military Institute od Medicine National Research Institute
Recruiting

Tele-Pulmonary Rehabilitation For COPD Patients Living in Peripheral Areas

June 24, 2026

Conditions: COPD (Chronic Obstructive Pulmonary Disease); Rehabilitation; Peripheral
Interventions: Other: Tele-Rehabilitation
Sponsors: Tel-Aviv Sourasky Medical Center; The Israel National Institute For Health Policy Research
Not yet recruiting

Beetroot Extract and Quality of Life in Adults Aged 75 and Over

June 24, 2026

Conditions: Cardiovascular Health; Functional Health; Cognitive Function Decline; Physical Performance Decline in Older Adults
Interventions: Dietary Supplement: Beetroot Extract Supplementation; Dietary Supplement: Placebo group: nitrate-depleted beetroot juice
Sponsors: Fundacion Miguel Servet
Recruiting

Effects of Resonant Breathing on Blood Pressure, Heart Rate and Perceived Stress

June 24, 2026

Conditions: Hypertension
Interventions: Combination Product: Resonant breathing
Sponsors: Riphah International University
Completed

AI-ECG for One-Year Mortality Risk Prediction

June 24, 2026

Conditions: Electrocardiogram; Mortality Risk Prediction
Interventions: Device: Chang Gung ECG Mortality Risk Prediction Software (Model: CGMH-DRP-001)
Sponsors: National Defense Medical Center, Taiwan; Kaohsiung Armed Forces General Hospital; Taipei Medical University WanFang Hospital
Completed

Continuous ESP Block in Patients Undergoing CABG Surgery.

June 24, 2026

Conditions: Erector Spinae Plane Block
Interventions: Drug: Ropivacaine; Drug: Standard Postoperative Analgesics; Drug: Placebo (0.9% Sodium Chloride)
Sponsors: Instituto do Coracao
Recruiting

LBBP + CSP Versus LBBP Alone for Cardiac Resynchronization Therapy

June 24, 2026

Conditions: Heart Failure Low Output
Interventions: Device: Left Bundle Branch Optimized CRT; Device: Stimulation of the left bundle branch area (LBBAP)
Sponsors: Clinica Cardio VID
Active, not recruiting

The Effect Of Paın And Anxıety Durıng Coronary Angıography

June 24, 2026

Conditions: Coronary Angiography (CAG); Nursing
Interventions: Behavioral: Stress Ball; Behavioral: Music Therapy
Sponsors: Manisa Celal Bayar University
Completed

Effect of Molar Replacement on Glycemic Control in Adults With Uncontrolled Type 2 Diabetes

June 24, 2026

Conditions: Type 2 Diabetes
Interventions: Procedure: Replacement of one pair of molars
Sponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting

Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety

June 24, 2026

Conditions: Neurodevelopmental Disorder (Diagnosis)
Interventions: Device: Virtual reality headset; Other: standard dental care
Sponsors: Semmelweis University
Enrolling by invitation

The Effect of Esketamine on Postoperative Cognitive Function in Elderly Patients Undergoing Oral and Maxillofacial Surgery

June 24, 2026

Conditions: Perioperative Neurocognitive Disorders
Interventions: Drug: esketamine; Drug: Normal Saline
Sponsors: Xijing Hospital
Not yet recruiting

Adapting Enhanced Supports to Improve Patient Adherence to Secondary Antibiotic Prophylaxis for Rheumatic Heart Disease

June 24, 2026

Conditions: Rheumatic Heart Disease in Children
Interventions: Behavioral: CHW Delivered SAP Adherence Supports
Sponsors: Children's Hospital Medical Center, Cincinnati; American Heart Association; Menzies School of Health Research; University of Washington; Uganda Heart Institute; Federal University of Minas Gerais
Not yet recruiting

Fasting, Exercise, and Diet to Activate Autophagy in Depression

June 24, 2026

Conditions: Depression - Major Depressive Disorder; Overweight (BMI > 25)
Interventions: Procedure: Performance test
Sponsors: University of Zurich; ETH Zurich; University Hospital, Bonn
Not yet recruiting

Subtransverse Process Interligamentary Plane Block Versus Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block for Analgesia in Pediatric Thoracotomy

June 24, 2026

Conditions: Subtransverse Process Interligamentary Plane Block; Rhomboid Intercostal Block; Sub-Serratus Plane Block; Analgesia; Pediatric Thoracotomy
Interventions: Other: Standard intravenous analgesia; Other: Subtransverse process interligamentary plane block; Other: Rhomboid intercostal block (RIB) combined with sub-serratus plan block group
Sponsors: Tanta University
Recruiting

Artificial Voice Analysis and Telemonitoring for Heart Failure. A Feasibility Study

June 24, 2026

Conditions: Heart Failure
Interventions: Other: AVATAR-SC; Drug: Levosimendan
Sponsors: Niguarda Hospital
Not yet recruiting

Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation

June 24, 2026

Conditions: Lower Limb Amputation Above Knee; Below Knee Amputation
Interventions: Device: Blood pressure cuff; Device: Neuromuscular Electrical Stimulation
Sponsors: University of Illinois at Chicago
Not yet recruiting

Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS

June 24, 2026

Conditions: Kidney Calculi; Urolithiasis; Urinary Tract Infections
Interventions: Procedure: Standard Retrograde Intrarenal Surgery; Drug: Gentamicin Irrigation; Device: Suction-Enabled Ureteral Access Sheath
Sponsors: Hitit University
Recruiting

Safety and Efficacy of B/F/TAF in Pregnancy

June 24, 2026

Conditions: HIV
Interventions: Drug: BIC+FTC+TAF
Sponsors: Shi Zou
Enrolling by invitation

Cardiorenal Syndrome: Characteristics and Prognostic Impact in Advanced Heart Failure

June 24, 2026

Conditions: Advanced Heart Failure; Cardiorenal Syndrome
Interventions: Other: Cardiorenal syndrome follow-up
Sponsors: Hospices Civils de Lyon
Not yet recruiting

Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain

June 24, 2026

Conditions: Body Temperature Changes; Heat Stress; Heat Exposure; Heat Fatigue; Hypoxia, Altitude; Work Related Stress; Physiological Stress
Interventions: Other: Simulated Occupational heat exposure under normoxic conditions; Other: Simulated Occupational heat exposure under hypoxic conditions
Sponsors: University of Ottawa
Recruiting

Home Air Pollution in Children With Cystic Fibrosis Study

June 24, 2026

Conditions: Cystic Fibrosis (CF)
Sponsors: Seattle Children's Hospital; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Impedance Plethysmography Based Deep Vein Thrombosis Monitoring During Catheter-directed Thrombolysis

June 24, 2026

Conditions: Deep Vein Thrombosis (DVT)
Interventions: Device: Impedance plethysmography IPG; Device: Venous Occlusion Plethysmography VOP; Other: Breathing and leg movement exercise
Sponsors: Tampere University; Tampere University Hospital
Recruiting

Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses

June 24, 2026

Conditions: Burnout; Sleep Disturbance; Occupational Stress; Mental Health; Nurse Retention; Fatigue
Interventions: Diagnostic Test: Non-Invasive Sleep Monitoring
Sponsors: Kaohsiung Armed Forces General Hospital
Not yet recruiting

Rapid Microaxial Flow Pump Support and Escalation in Patients With Myocardial Infarction Associated Cardiogenic Shock and Persistent Need of Hemodynamic Support

June 24, 2026

Conditions: Cardiogenic Shock Post Myocardial Infarction
Interventions: Device: Escalation to more capable microaxial flow-pump (Impella 5.5)
Sponsors: University Hospital of Cologne; Johnson & Johnson
Recruiting

ASSESSMENT OF THE NATURAL HISTORY AND PROGNOSTIC FACTORS OF THERAPEUTIC RESPONSE IN SUB-PHENOTYPES OF PATIENTS WITH OBESITY: THE BOLOBE STUDY

June 24, 2026

Conditions: Obese Adults; Overweight , Obesity
Sponsors: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Recruiting

CORonary Thrombus Modification to Prevent MIcrovascular Damage in Patients With ST-segment Elevation Myocardial Infarction (The CORMI Trial)

June 24, 2026

Conditions: ST Elevation Myocardial Infarction; Coronary Microvascular Dysfunction; Percutaneous Coronary Intervention
Interventions: Procedure: Coronary thrombus modification; Procedure: Standard stent implantation
Sponsors: Odense University Hospital
Not yet recruiting

MCG for Non-Obstructive Myocardial Ischemia

June 24, 2026

Conditions: Myocardial Ischemia
Interventions: Device: Magnetocardiography
Sponsors: Qilu Hospital of Shandong University
Recruiting

Pulmonary Hypertension (PH) Biorepository for Translational Research

June 24, 2026

Conditions: Pulmonary Hypertension
Sponsors: National Institutes of Health Clinical Center (CC)
Not yet recruiting

Epidemiological Cluster Evaluation in Patients Admitted to Internal Medicine, With at Least One of the Following Diagnoses: Heart Failure, COPD, Renal Failure. The FADOI IN-CluDiMI Study

June 24, 2026

Conditions: Heart Failure; Chronic Obstructive Pulmonary Disease (COPD); Chronic Kidney Disease (CKD)
Sponsors: Fadoi Foundation, Italy
Completed

Moderate Intensity vs High Intensity Interval Training in Women With Heart Failure

June 23, 2026

Conditions: Heart Failure
Interventions: Other: moderate-intensity aerobic training; Other: High-intensity interval training
Sponsors: Riphah International University
Not yet recruiting

Epcoritamab in Combination With Dose Adjusted EPOCH-R for High-risk Burkitt Lymphoma (BL), The BEDROCK Study

June 23, 2026

Conditions: Adult Burkitt Lymphoma
Interventions: Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Drug: Cyclophosphamide; Drug: Doxorubicin; Procedure: Echocardiography Test; Biological: Epcoritamab; Drug: Etoposide; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography; Drug: Prednisone; Biological: Rituximab; Drug: Vincristine
Sponsors: AIDS Malignancy Consortium; National Cancer Institute (NCI)
Not yet recruiting

Coronary Artery Calcium Score in HIV Mexican Population (The CACsHIVMex Study)

June 23, 2026

Conditions: HIV - Human Immunodeficiency Virus
Interventions: Diagnostic Test: Simple coronary CT scan
Sponsors: Instituto Mexicano del Seguro Social
Not yet recruiting

Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial Prospective

June 23, 2026

Conditions: Congenital Heart Disease; Pulmonary Hypertension; Heart Failure; Coronary Heart Disease (CHD); Apple Watch
Interventions: Device: Apple Watch Series 9
Sponsors: The University of Hong Kong
Not yet recruiting

Objective Sleep Characteristics and Neoadjuvant Immunotherapy Response in Gastric/GEJ Cancer

June 23, 2026

Conditions: Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Sleep; Pathological Response
Interventions: Other: Not applicable- observational study
Sponsors: West China Second University Hospital
Not yet recruiting

Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac Surgery

June 23, 2026

Conditions: Valve Heart Disease; Coronary Artery Disease; Coronary Heart Disease; Aortic Diseases
Interventions: Procedure: Cardiac surgey
Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University
Recruiting

A Phase 1 Study to Evaluate the Relative Bioavailability of Octreotide Acetate Tablets(T25) Compared to MYCAPSSA® and The Food Effect on Pharmacokinetics Of Octreotide Acetate Tablets(T25)

June 23, 2026

Conditions: Acromegaly
Interventions: Drug: T25-Fast; Drug: Mycapssa; Drug: T25-Fed
Sponsors: Triastek (Shanghai) Limited; Zibo Central Hospital
Not yet recruiting

Machine Learning Prediction of Respiratory Muscle Changes and Ventilatory Responses After Incretin-Based Therapy in Obesity

June 23, 2026

Conditions: Obesity (BMI>30)
Interventions: Other: Incretin-based therapy
Sponsors: Biruni University
Not yet recruiting

Neuroplastic Changes Due to an Exercise Intervention That Aid in Lower Limb Recovery After Subcortical Stroke

June 23, 2026

Conditions: Subcortical Lesions; Stroke
Interventions: Behavioral: HIIT intervention
Sponsors: Emory University; American Heart Association
Not yet recruiting

Cardiovascular Risk in Patients With IBD

June 23, 2026

Conditions: Ulcerative Colitis (UC); Crohn's Diseases; Cardiovascular Risk
Sponsors: IRCCS Policlinico S. Donato; IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo
Not yet recruiting

Frequency Effects of Transcutaneous Trigeminal Nerve Stimulation (eTNS) on Brain and Autonomic Function

June 23, 2026

Conditions: Healthy Volunteers; fMRI Research
Interventions: Device: 2Hz Transcutaneous Trigeminal Nerve Stimulation; Device: 120Hz Transcutaneous Trigeminal Nerve Stimulation; Device: Sham Transcutaneous Trigeminal Nerve Stimulation
Sponsors: Xidian University
Recruiting

Development of a Pharmacogenomic Panel for Early Detection of Chemotherapy- and Immunotherapy-Induced Cardiotoxicity.

June 23, 2026

Conditions: Cardiotoxicity
Sponsors: Beneficência Portuguesa de São Paulo
Recruiting

Influence of Superficial Parasternal Intercostal Plane Block on Internal Thoracic Artery Caliber to Facilitate Surgical Harvesting in CABG

June 23, 2026

Conditions: Pain Management; Parasternal Block; CABG Graft Integrity
Interventions: Drug: Bupivacaine
Sponsors: Ain Shams University
Not yet recruiting

The Prevalence of Hyperglycemia in Surgical Patients With Pre-diabetes

June 23, 2026

Conditions: Prediabetes or Diabetes; Surgery Complications; Non-Cardiac/ Non-Thoracic Surgery; Stress Hyperglycemia
Sponsors: University of Calgary
Not yet recruiting

Propofol vs. Ciprofol for Anesthesia Induction in Frail Elderly Patients

June 23, 2026

Conditions: Hypotension
Interventions: Drug: Ciprofol; Drug: Propofol
Sponsors: General Hospital of Ningxia Medical University
Not yet recruiting

Early Warning of Structural Complications in Perimembranous VSD

June 23, 2026

Conditions: Congenital Heart Disease (CHD); Ventricular Septal Defects (VSD)
Sponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Active, not recruiting

Percutaneous Pulmonary Artery Denervation (PADN) for the Treatment of Pulmonary Hypertension After Transcatheter Mitral Valve Edge-to-Edge Repair (M-TEER): A Prospective Cohort Study

June 23, 2026

Conditions: Pulmonary Hypertension; Pulmonary Hypertension Associated With HFpEF
Interventions: Device: Percutaneous Pulmonary Artery Denervation (PADN); Drug: Control group (receiving standard medical therapy alone)
Sponsors: Xiamen Cardiovascular Hospital, Xiamen University
Recruiting

Effect of Preoperative CIMT on Hemodynamics During Liver Transplantation

June 23, 2026

Conditions: Liver Transplantation; Carotid Intima-media Thickness
Sponsors: Dicle University
Recruiting

Oliceridine vs Sufentanil for Cough During Anesthesia Induction

June 23, 2026

Conditions: Cough; Anesthesia
Interventions: Drug: Oliceridine; Drug: Sufentanil
Sponsors: Shiyou Wei; Tianmen First People's Hospital
Not yet recruiting

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

June 23, 2026

Conditions: Breast Cancer; Non-small Cell Lung Cancer (NSCLC); Gastric/Gastroesophageal Junction (GEJ) Cancer; Bladder Cancer
Interventions: Diagnostic Test: [68Ga]Ga-DWJ155; Drug: [177Lu]Lu-DWJ155
Sponsors: Novartis Pharmaceuticals
Recruiting

Combined Training (Strength and Endurance) and the Serum Levels of Myostatin and Hormone-sensitive Lipase in Overweight and Obese Men

June 23, 2026

Conditions: Overweight (BMI > 25); Obesity (BMI>30)
Interventions: Behavioral: Upper Body Combined Training; Behavioral: Lower Body Combined Training
Sponsors: Arya Habibi
Completed

PERCEIVE-Outreach: A Scalable, Risk-Based Model for Managing Persistent Cardiovascular Impact in Long COVID

June 22, 2026

Conditions: Long COVID
Interventions: Other: PERCEIVE-Outreach Intervention
Sponsors: University of Tasmania; Baker Heart and Diabetes Institute; Ochre Health
Recruiting

Metformin Withdrawal In Metabolic Syndrome

June 22, 2026

Conditions: Metabolic Syndrome (MetS); Glucose Intolerance
Interventions: Behavioral: Temporary Metformin Withdrawal
Sponsors: University of Castilla-La Mancha
Recruiting

Motivational Interviewing After Coronary Stenting

June 22, 2026

Conditions: Coronary Artery Disease
Interventions: Behavioral: Motivational Interviewing
Sponsors: Biruni University
Completed

Cardiovascular Assessment 5 Years After MIS-C

June 22, 2026

Conditions: Multisystem Inflammatory Syndrome in Children (MIS-C); SARS-CoV-2 Infection
Sponsors: Medical University of Warsaw
Recruiting

A Study to Evaluate Efficacy and Safety of BGM0504 Tablets in Overweight or Obese Participants Without Diabetes

June 22, 2026

Conditions: Overweight or Obese Participants Without Diabetes
Interventions: Drug: BGM0504 tablets; Drug: BGM0504 tablets; Drug: BGM0504 tablets; Drug: BGM0504 tablets; Drug: BGM0504 placebo
Sponsors: BrightGene Bio-Medical Technology Co., Ltd.
Not yet recruiting

Effects of a Transitional Care Program on Depression, Self-Efficacy, and Self-Care in Patients With Heart Failure

June 22, 2026

Conditions: Heart Failure and Reduced Ejection Fraction; Transitional Care
Interventions: Behavioral: Structured Transitional Care Program; Other: Usual Care
Sponsors: Chang Gung Memorial Hospital
Completed

eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF

June 22, 2026

Conditions: Heart Failure and Preserved Ejection Fraction; Obesity & Overweight; Heart Failure
Interventions: Behavioral: Digital lifestyle education program; Other: Usual Care
Sponsors: Maimónides Biomedical Research Institute of Córdoba; Sociedad Andaluza de Cardiología
Not yet recruiting

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD

June 22, 2026

Conditions: Chronic Kidney Disease Mineral and Bone Disorder; Hypertension; Diabetes; Dyslipidemia; Atherosclerotic Cardiovascular Disease (ASCVD); Chronic Kidney Disease (Stage 3)
Interventions: Drug: Low-dose Colchicine at 0.5mg daily; Other: Usual Care
Sponsors: University of Texas Southwestern Medical Center
Not yet recruiting

Effect of Minimally Invasive Extracorporeal Circulation on Optic Nerve Sheath Diameter and Stroke Incidence in Isolated Open Heart Surgery

June 22, 2026

Conditions: Stroke; Cardiac Surgery; Cardiopulmonary Bypass
Sponsors: Bursa Yuksek Ihtisas Training and Research Hospital
Active, not recruiting

Left Atrial and Left Ventricular Structural and Functional Evaluation by CCTA for Predicting Post-Ablation Outcomes in Patients With Atrial Fibrillation

June 22, 2026

Conditions: Atrial Fibrillation (AF)
Sponsors: Nanjing First Hospital, Nanjing Medical University
Withdrawn

Risk Factor Assessment for Acute Pulmonary Hypertension Crisis

June 22, 2026

Conditions: Pulmonary Hypertension; Pulmonary Hypertension Crisis
Sponsors: Peking Union Medical College Hospital
Recruiting

A Study of Ziresovir (AK0529) in High-risk Adult With Respiratory Syncytial Virus (RSV) Infection.

June 22, 2026

Conditions: Respiratory Syncytial Virus Infections
Interventions: Drug: Ziresovir (AK0529); Drug: Placebo
Sponsors: Shanghai Ark Biopharmaceutical Co., Ltd.
Recruiting

A Study of LTX-002 in Adult Participants With Amyotrophic Lateral Sclerosis

June 22, 2026

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Drug: LTX-002; Other: Placebo (aCSF)
Sponsors: Leal Therapeutics, Inc
Recruiting

A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma

June 22, 2026

Conditions: Healthy Volunteer Study; Healthy Adults; Healthy Participants; Asthma
Interventions: Drug: PF-08103402; Drug: Placebo; Drug: Midazolam
Sponsors: Pfizer
Not yet recruiting

Timing of Serratus Anterior Plane Block in Mastectomy Surgery

June 22, 2026

Conditions: Quality of Recovery After Mastectomy; Serratus Anterior Plane Block; Postoperative Pain; Mastectomy
Interventions: Procedure: Ultrasound-Guided Serratus Anterior Plane Block; Drug: Bupivacaine
Sponsors: Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Not yet recruiting

Presentation of Young Adults With and Without Joint Hypermobility

June 22, 2026

Conditions: Hypermobile Ehlers-Danlos Syndrome; Postural Orthostatic Tachycardia Syndrome (POTS)
Sponsors: Clarkson University
Not yet recruiting

Effect of Mobile-Based Home Cardiac Rehabilitation on Coronary Plaque

June 22, 2026

Conditions: Coronary Artery Disease (CAD); Coronary Stenosis
Interventions: Behavioral: mHealth-based Cardiac Rehabilitation Program
Sponsors: China National Center for Cardiovascular Diseases
Recruiting

Italian YOLO: A Web-Based ACT Mental Health Promotion Intervention for University Students

June 22, 2026

Conditions: Psychological Distress; Psychological Wellbeing; Academic Stress
Interventions: Behavioral: Italian YOLO
Sponsors: University of Bologna; The University of Queensland
Not yet recruiting

Gait Adaptation Study

June 22, 2026

Conditions: Aging
Interventions: Behavioral: Gait Adaptation Training; Behavioral: Basic Physical Training
Sponsors: Rutgers, The State University of New Jersey
Recruiting

A Clinical Study of X-Clip Mitral Valve Clip System and Steerable Guide System for Transcatheter Mitral Valve Repair of Degenerative Mitral Regurgitation

June 22, 2026

Conditions: Transcatheter Mitral Valve Repair of Degenerative Mitral Regurgitation
Interventions: Device: X-Clip Treatment for Degenerative Mitral Regurgitation
Sponsors: Shenzhen Lifevalve Medical Scientific Co., Ltd.; Lifetech Scientific (Shenzhen) Co., Ltd.
Not yet recruiting

Polyethylene Bag vs Prewarmed Blanket for Preventing Neonatal Hypothermia During Transfer

June 22, 2026

Conditions: Hypothermia Neonatal; Premature Birth; Neonatal
Interventions: Device: Neonatal Polyethylene Bag; Other: Prewarmed Blanket
Sponsors: Mario Adrián Tienda Vázquez
Completed

Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)

June 22, 2026

Conditions: Poly Cystic Ovary Syndrome; Overweight , Obesity
Interventions: Behavioral: Physical activity
Sponsors: University Hospital, Clermont-Ferrand; SMR Nutrition Obésité UGECAM; Laboratoire AME2P
Not yet recruiting

Assessment of CT-FFR in Patients With CCS: A Prospective Multicenter Cohort Study

June 22, 2026

Conditions: Coronary Artery Disease
Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University
Recruiting

Consecutive Occupational Heat Exposure With and Without Overnight Cooling

June 18, 2026

Conditions: Body Temperature Changes; Heat Stress; Heat Exposure; Heat Fatigue; Work Related Stress; Physiological Stress
Interventions: Other: Simulated occupational heat exposure with recovery at recommended indoor temperature limit; Other: Simulated occupational heat exposure with recovery in an overheated indoor environment
Sponsors: University of Ottawa
Not yet recruiting

Respiratory Muscle Training and Walking Exercise in Women Recovering From COVID-19 Pneumonia

June 18, 2026

Conditions: COVID-19 Pneumonia; Respiratory Symptoms
Interventions: Behavioral: Respiratory Muscle Training; Behavioral: Walking Exercise
Sponsors: Hitit University
Completed

Modifiable Risk Factors for Cognitive Dysfunction in Patients With Coronary Heart Disease

June 18, 2026

Conditions: Coronary Heart Disease; Cognitive Impairment, Mild
Sponsors: Beijing Anzhen Hospital
Not yet recruiting

Effects of Snoezelen Multisensory Therapy on Older Adults With Dementia

June 18, 2026

Conditions: Dementia
Interventions: Behavioral: Snoezelen Multisensory Therapy; Behavioral: Standard Therapy
Sponsors: University of Primorska
Completed

Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock

June 18, 2026

Conditions: Septic Shock; Sepsis; Critical Illness
Interventions: Drug: Dexmedetomidine Intravenous Infusion
Sponsors: First Affiliated Hospital of Wannan Medical College
Not yet recruiting

Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or Obesity

June 18, 2026

Conditions: Obesity & Overweight; Coronary Heart Disease
Interventions: Drug: Mazdutide; Drug: Placebo
Sponsors: China National Center for Cardiovascular Diseases
Not yet recruiting

Effect of a Focused Point-of-care Ultrasonography Screening Protocol in Hospitalized Patients

June 18, 2026

Conditions: Heart Failure, Congestive; Renal Failure Acute Chronic; Liver Cirrhosis; Sepsis; Edema, Pulmonary; Establish a Real-time Focused Ultrasound Examination Protocol for Routine Assessment of Hospitalized Patients; Edema
Sponsors: National Taiwan University Hospital
Active, not recruiting

Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down Syndrome

June 18, 2026

Conditions: Obstructive Sleep Apnea; Down Syndrome (Trisomy 21)
Interventions: Device: CURAPROX pacifier use; Other: Pacifier diary; Diagnostic Test: Polysomnography (PSG) to explore OSA; Other: Non-nutritive sucking recording; Other: Oro-myo-functional clinical evaluation; Behavioral: Neurocognitive evaluation; Other: Sleep Disturbance Scale for Children; Other: Sleep Hygien Scale for Children; Other: PedsQL-Infants
Sponsors: Hospices Civils de Lyon
Not yet recruiting

Prospective Investigation of Cirrhotic Cardiomyopathy in Humans

June 18, 2026

Conditions: Cirrhotic Cardiomyopathy
Sponsors: Vanderbilt University Medical Center; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Molecular Subtype-Guided Postoperative Radiotherapy for Phyllodes Tumor of the Breast: A Randomized Controlled Trial

June 18, 2026

Conditions: Radiotherapy, Adjuvant; Phyllodes Breast Tumor; Prognosis; Molecular Typing
Interventions: Radiation: Postoperative Radiotherapy (PORT)
Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Not yet recruiting

The Impact of Masseter Muscle Thickness on the Feeding Process in Preterm Infants in Ultrasound Assessment

June 18, 2026

Conditions: Premature Infants
Sponsors: Polish Mother Memorial Hospital Research Institute
Not yet recruiting

FAPl Imaging Assessment of Revascularization Outcome in Ischemic Heart Failure

June 18, 2026

Conditions: Ischemic Heart Failure
Interventions: Procedure: PCI (ercutaneous coronary intervention) and CABG (coronary artery bypass grafting, commonly known as heart bypass surgery)
Sponsors: Beijing Chao Yang Hospital
Recruiting

A Personalized Mobile Application Providing Temperature-Related Health Risk Warnings and Protective Recommendations for Patients With Chronic Obstructive Pulmonary Disease

June 18, 2026

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Other: Mobile Application-Based Personalized Temperature Health Risk Early Warning Intervention
Sponsors: Tiantian Li
Not yet recruiting

Investigating the Transcutaneous vs. Transcranial Mechanisms of Trigeminal Nerve Stimulation (eTNS) Using fMRI

June 18, 2026

Conditions: Healthy Volunteers; Neurophysiology; fMRI Research
Interventions: Drug: Topical Lidocaine; Device: Direct Current eTNS (DC-eTNS); Device: Sham DC-eTNS
Sponsors: Xidian University
Recruiting

Human Mass Balance Study of [¹⁴C]HRS-1893

June 18, 2026

Conditions: Cardiomyopathies
Interventions: Drug: [14C]HRS-1893
Sponsors: Shandong Suncadia Medicine Co., Ltd.
Not yet recruiting

Occult Vasoplegia in Normotensive Sepsis: Early Prediction With Diastolic Index and Lactate

June 18, 2026

Conditions: Sepsis; Vasoplegia; Septic Shock
Sponsors: Hospital H+ Queretaro
Completed

Effects of Anisodamine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock

June 18, 2026

Conditions: Septic Shock; Sepsis; Critical Illness
Interventions: Drug: Anisodamine intravenous infusion
Sponsors: First Affiliated Hospital of Wannan Medical College; The First Affiliated Hospital of Bengbu Medical University
Not yet recruiting

A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants

June 18, 2026

Conditions: Healthy Volunteers; Heart Failure
Interventions: Drug: CDR132L (i.v.); Drug: CDR132L (s.c.)
Sponsors: Novo Nordisk A/S
Not yet recruiting

Cardiovascular Abnormalities in Children With Attention-deficit/Hyperactivity Disorder

June 18, 2026

Conditions: ADHD - Combined Type
Interventions: Diagnostic Test: echocardiography and ECG
Sponsors: Assiut University
Not yet recruiting

COMPARE-VENT Feasibility Pilot Study

June 18, 2026

Conditions: Respiration Failure; Cardio Vascular Disease; Cardiogenic Pulmonary Oedema; Critical Illness; Mechanical Ventilation; Cardiogenic Shock; Cardiopulmonary
Interventions: Other: Volume Controlled Mode; Other: Pressure Controlled Mode
Sponsors: Mayo Clinic
Not yet recruiting

Effects of VR on Preanesthetic Anxiety

June 18, 2026

Conditions: VR; Preanesthetic Anxiety; Uncertainty
Interventions: Behavioral: Virtual Reality Intervention
Sponsors: Mackay Memorial Hospital; Mackay Medical College
Not yet recruiting

Physical Activity in Bed Rest Hospitalized High-Risk Pregnant Women.

June 18, 2026

Conditions: Bed Rest; Pregnancy; Pregnancy Complications
Interventions: Other: Exercise
Sponsors: Hospital Clinic of Barcelona
Not yet recruiting

Use of Force Feedback Instruments With the da Vinci Surgical System, Model IS5000 for Mitral Valve Repair

June 18, 2026

Conditions: Mitral Regurgitation (MR)
Interventions: Device: Mitral Valve Repair including the use of Force Feedback instruments
Sponsors: Intuitive Surgical
Not yet recruiting

Pleth Variability Index Monitoring in Pediatric Craniosynostosis Surgery

June 18, 2026

Conditions: Craniosynostosis
Sponsors: Muzaffer GENCER; Başakşehir Çam & Sakura City Hospital
Recruiting

Taurine and Nitrate Supplementation on Thermoregulatory in T2DM

June 18, 2026

Conditions: Type 2 Diabetes
Interventions: Dietary Supplement: taurine; Dietary Supplement: Beetroot and taurine; Dietary Supplement: Placebo
Sponsors: University of Portsmouth; Swansea University; Portsmouth Hospitals NHS Trust; University of Southampton
Not yet recruiting

Effects of Afternoon Napping, Caffeine and Recovery on Evening Athletic Performance

June 18, 2026

Conditions: Athletic Performance; Sports Performance; Exercise Performance; Circadian Rhythm
Interventions: Behavioral: Afternoon Nap; Dietary Supplement: Caffeine; Combination Product: Personalised Recovery Protocol; Other: Placebo
Sponsors: The Higher Institute of Sport and Physical Education of Sfax
Completed

Feasibility of a Remotely Delivered Step Count Intervention in Chronic Stroke

June 18, 2026

Conditions: Stroke; Ischemic Stroke; Hemorrhagic Stroke
Interventions: Behavioral: Physical Activity Chats after Stroke (PA-ChatS)
Sponsors: University of Minnesota
Not yet recruiting

Coherence Breathing Before Cardiopulmonary Exercise Testing

June 18, 2026

Conditions: Breathing Rate
Interventions: Behavioral: Coherence Breathing; Behavioral: Spontaneous Breathing
Sponsors: Human Performance Lab of Monmouth University
Not yet recruiting

CGM-guided Patch Pump vs Basal-Bolus Injection for Steroid-Induced Hyperglycemia in Sudden Sensorineural Hearing Loss: SHIP Trial

June 17, 2026

Conditions: Sudden Sensorineural Hearing Loss (SSNHL); Prediabetes / Type 2 Diabetes
Interventions: Device: CareLevo Patch-type Insulin Pump; Drug: Insulin Glargine U-100 (Lantus); Drug: Fast-acting Insulin Aspart (Fiasp); Device: CareSens Air Continuous Glucose Monitor
Sponsors: Hallym University
Not yet recruiting

Effects of Passive Recovery Methods After High-Intensity Cycling Exercise

June 17, 2026

Conditions: Young Adult Health; Young Adult Females
Interventions: Behavioral: High-Intensity Cycling Exercise Protocol; Device: Doctor Life MK400L Sequential Intermittent Compression Device; Device: Intelect Neo Therapy System with Chattanooga Intelect Neo Vacuum Module; Other: Kinesiology Taping; Other: Passive Rest; Other: Classical Massage
Sponsors: Pamukkale University
Not yet recruiting

Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity

June 17, 2026

Conditions: Obesity (BMI>30); Insulin Resistance
Interventions: Drug: human insulin
Sponsors: University of Missouri-Columbia
Not yet recruiting

Baxdrostat and Ventricular Remodeling

June 17, 2026

Conditions: Cardiac Remodeling
Interventions: Drug: Baxdrostat; Drug: Placebo
Sponsors: Subodh Verma; AstraZeneca
Not yet recruiting

Withings Heart Function Risk Notification Retrospective Study

June 17, 2026

Conditions: Heart Failure
Interventions: Device: Withings Heart Function Risk Notification (HFRN); Other: Claims-based heart-failure adjudication (reference standard)
Sponsors: Withings
Not yet recruiting

Comparison Of The Effects Of Swedish Massage With Natural Oils

June 17, 2026

Conditions: Childbirth; Aromatherapy; Pain Management; Fear; Anxiety; Midwifery
Interventions: Other: Aromatherapy and Massage Care for labor pain management
Sponsors: Kutahya Health Sciences University
Completed

Stellate Ganglion Block and Prognosis of Neurological Function After Subarachnoid Hemorrhage

June 17, 2026

Conditions: Aneurysmal Subarachnoid Hemorrhage; Stellate Ganglion Block; Neurological Prognosis
Interventions: Procedure: Intervention group
Sponsors: Beijing Tiantan Hospital
Not yet recruiting

Prospective Multicentre Observational Registry of Peri-procedural Anaesthesia, Sedation and Related Medication Exposure in Patients With Brugada Syndrome

June 17, 2026

Conditions: Brugada Syndrome (BrS); Ventricular Arrhythmia; Anesthesia; Sedation
Sponsors: Hospital Clinic of Barcelona
Not yet recruiting

Safety, Tolerability, and Preliminary Effectiveness of CTH120 in Fragile X Syndrome

June 17, 2026

Conditions: Fragile X Syndrome (FXS); Fragile X Syndrome
Interventions: Drug: CTH120; Other: CTH120 placebo hard capsules
Sponsors: Connecta Therapeutics, S.L.; Hospital del Mar Research Institute (IMIM); Corporacion Parc Tauli; Ministry of Science and Innovation, Spain; Astrum CRO, S.L.
Recruiting

Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns

June 17, 2026

Conditions: Subjective Cognitive Decline; Alzheimer Disease; Mild Cognitive Impairment; Cognitive Decline
Interventions: Device: High-frequency Transcranial Magnetic Stimulation (TMS); Behavioral: Digital Cognitive Training; Behavioral: Structured Physical Exercise; Other: Management of Modifiable Vascular and Behavioral Risk Factors
Sponsors: IRCCS San Raffaele
Not yet recruiting

Safety and Efficacy of Avalglucosidase Alfa in Patients With Non-classic Pompe Disease Aged ≥ 5 Years

June 17, 2026

Conditions: Glycogen Storage Disease Type II Late Onset; Pompe Disease (Late-onset); Pompe Disease Late-Onset; Pompe's Disease Juvenile Onset; Pompe Disease
Interventions: Drug: Avalglucosidase Alfa
Sponsors: Iris Plug; Sanofi
Active, not recruiting

A Study to Learn About How Safe BAY3389934 is and How it Affects Blood Clotting When Given Alone or With Aspirin in Healthy Participants

June 17, 2026

Conditions: Drug-drug Interaction
Interventions: Drug: BAY3389934; Drug: Aspirin
Sponsors: Bayer
Recruiting

Hemodynamic Effects of Norepinephrine Reduction on Critical Closing Pressure in Distributive Shock

June 17, 2026

Conditions: Distributive Shock; Hemodynamic Assessment; Critical Illness
Interventions: Other: Not applicable- observational study
Sponsors: Peking Union Medical College Hospital
Recruiting

The Effect of Using Weighted Blanket on Anxiety, Stress, Depression and Comfort Level Among Patients With Cancer Undergoing Intravenous Anticancer Therapy and Its Feasibility of Use by Nurses Compared to Routine Care

June 17, 2026

Conditions: Solid Cancers; Anxiety Depression; Stress
Interventions: Device: Weighted Blanket; Device: Regular Hospital Blanket
Sponsors: Sultan Qaboos Comprehensive Cancer Center
Recruiting

Precision Antithrombotic Therapy

June 17, 2026

Conditions: Non-valvular Atrial Fibrillation (NVAF); Venous Thromboembolism (VTE); MI(Myocardial Infarction); Ischemic Stroke
Interventions: Other: Not applicable- observational study
Sponsors: The Third Xiangya Hospital of Central South University; Renji Hospital, School of Medicine, Shanghai Jiao Tong University.; Xiangtan County People's Hospital; Taoyuan County People's Hospital; Hengyang Central Hospital; Second Affiliated Hospital of Shaoyang University; The First Affiliated Hospital of Nanhu University; Yongzhou Central Hospital; Shenzhen Second People's Hospital; First Affiliated Hospital of Xinjiang Medical University; The Second Affiliated Hospital of Hunan University of Chinese Medicine; Changsha First Hospital; Xiangya Changde Hospital; Jinshan Hospital Affiliated to Fudan University; Changsha Central Hospital; Hunan Provincial Rehabilitation Hospital; Hunan Cancer Hospital; The Second Affiliated Hospital of Nanhu University; Hunan Medical College General Hospital; Shanghai Minhang District Central Hospital; The Ninth People's Hospital of Shanghai Jiao Tong University School of Medicine; Fudan University Affiliated Shanghai Fifth People's Hospital Hospital; The First Affiliated Hospital of Shaoyang University of Science and Technology; Renji Hospital Pu Nan Branch, Affiliated to Shanghai Jiao Tong University School of Medicine; Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University); Eastern Theater Command General Hospital; Hunan Aerospace Hospital; The First Affiliated Hospital of Naval Medical University; Xiangtan Central Hospital; Fengxian District Central Hospital of Shanghai; Shanghai Yangpu District Shidong Hospital; The First Affiliated Hospital of HuNan University of Medicine; Huashan Hospital; Hunan Provincial Maternal and Child Health Care Hospital; Yueyang Central Hospital; The First Affiliated Hospital of Dalian Medical University; Jining Medical College Affiliated Hospital; Shanghai East Hospital
Enrolling by invitation

Study of Antihypertensive Treatment and Cardiovascular Risk in Chinese Prehypertensive Population

June 17, 2026

Conditions: High-normal Blood Pressure
Interventions: Drug: Telmisartan; Drug: Indapamide; Other: Placebo
Sponsors: Qilu Hospital of Shandong University
Completed

The Value of Partial Arterial Carbon Dioxide Pressure - End-Tidal Carbon Dioxide Gradient Courses in Predicting Acute Renal Injury in Critically Ill Patients on Mechanical Ventilation: A Novel Hemodynamic Marker?

June 17, 2026

Conditions: Acute Kidney Injury; Ventilated Patient in Intensive Care
Sponsors: Malatya Egitim Ve Arastirma Hastanesi
Completed

The Efficacy of Vitamin D Supplementation to Sustain Performance Outcomes

June 17, 2026

Conditions: Acute Stress Reaction
Interventions: Dietary Supplement: Vitamin D3 (Cholecalciferol); Dietary Supplement: Oral Placebo Tablet
Sponsors: Walter Reed Army Institute of Research (WRAIR)
Recruiting

The CARDIOPROTECT Trial

June 17, 2026

Conditions: Diffuse Large B-cell Lymphoma (DLBCL); Cardiotoxicity; Lymphoma
Interventions: Drug: Dexrazoxane; Drug: Dexrazoxane placebo; Drug: Doxorubicin; Drug: Liposomal Doxorubicin; Drug: Cyclophosphamide; Drug: Vincristine; Drug: Prednisone; Drug: Rituximab; Drug: Polatuzumab Vedotin
Sponsors: Beth Israel Deaconess Medical Center
Not yet recruiting

Effect of Virtual Reality During Femoral Sheath Removal

June 17, 2026

Conditions: Percutaneous Coronary Intervention; Femoral Sheath Removal
Interventions: Device: Virtual Reality; Other: Routine Care
Sponsors: Hasan Kalyoncu University
Completed

A Study to Evaluate the Safety of Dostarlimab in Adult Participants in India With Primary Advanced or Recurrent Endometrial Cancer

June 17, 2026

Conditions: Neoplasms, Endometrial
Interventions: Drug: Dostarlimab; Drug: Carboplatin; Drug: Paclitaxel
Sponsors: GlaxoSmithKline
Not yet recruiting

Dietary Tracking in Heart Failure

June 17, 2026

Conditions: Heart Failure; NYHA Class II Heart Failure; NYHA Class III Heart Failure
Interventions: Behavioral: Limiting Ultraprocessed Food (UPF) in Diet
Sponsors: The Cleveland Clinic
Recruiting

Contactless Ultrasound Data Acquisition in Emergency Departments to Discriminate the Origin of Dyspnea and Chest Pain

June 17, 2026

Conditions: Dyspnea; Chest Pain
Interventions: Device: All patients from both groups will be imaged with airborne ultrasound device
Sponsors: Austral Diagnostics
Not yet recruiting

Mobile-Based Telemedicine and Health-Related Quality of Life Among Patients With Chronic Heart Failure (MOBILE-HF)

June 17, 2026

Conditions: Chronic Heart Failure; Health Related Quality of Life
Interventions: Other: Supportive Care
Sponsors: Select College
Recruiting

The Effect of a Nap Protocol on the Cognitive Abilities of Experienced Teachers

June 17, 2026

Conditions: No Disease or Condition is Being Studied; The Aim: to Determine the Impact of a 25-minute Nap on Cognitive Function
Interventions: Procedure: the nap routine
Sponsors: Higher Institute of Sport and Physical Education, Ksar-Said; Institut Supérieur du Sport et de l'Education Physique de Ksar-Saïd
Completed

Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism

June 17, 2026

Conditions: Healthy Adult
Interventions: Dietary Supplement: Niagen®
Sponsors: Massachusetts General Hospital; Mclean Hospital; Martinos Center for Biomedical Imaging
Recruiting

Hydration & Female Life Stages

June 17, 2026

Conditions: Dehydration; Menstruation; Pre-menopause; Peri-menopausal Women; Post-menopausal Women; Hydration
Interventions: Other: placebo beverage; Other: electrolyte beverage
Sponsors: PepsiCo Global R&D
Recruiting

Cryoablation for Monomorphic Ventricular Tachycardia (VTS)

June 17, 2026

Conditions: Ventricular Tachycardia, Sustained; Ventricular Tachycardia, Monomorphic
Interventions: Device: Ultra Low Temperature Ablation (ULTA)
Sponsors: Adagio Medical
Not yet recruiting

THE EFFECT OF 'RHYTHMİC SKİN TAPPİNG' AND INTERNAL VİBRATİON APPLİED PROXİMAL TO THE PROCEDURE SİTE ON PAİN AND FEAR PERCEPTİON DURİNG PEDİATRİC PERİPHERAL VENİPUNCTURE

June 16, 2026

Conditions: Procedural Pain; Acute Pain; Needle-Related Pain and Distress; Fear; Anxiety; Phlebotomy
Interventions: Behavioral: Rhythmic Skin Tapping; Behavioral: Internal Vibration (Humming)
Sponsors: Akdeniz University
Not yet recruiting

Stroke Rehabilitation Through Intensive Exercise

June 16, 2026

Conditions: Stroke; Rehabilitation; Rehabilitation Outcome; Aerobic Exercise; Telerehabilitation; Gait Impairment in Stroke Patients
Interventions: Behavioral: LE-mCIMT-EXE; Behavioral: LE- mCIMT-TAU
Sponsors: The Swedish School of Sport and Health Sciences; Neurology clinic, Stockholm; Neurocampus, Stockholm; Furuhöjden rehabcenter; Camp pro Ortopedteknik
Not yet recruiting

Effects of Myofascial Release on Cardiac Patients After Median Sternotomy

June 16, 2026

Conditions: Aortic Aneurysm and Dissection; Coronary Artery Disease (CAD); Valve Heart Disease
Interventions: Behavioral: myofascial release+Routine Physical Therapy; Behavioral: Routine Physical therapy
Sponsors: Siou-Pin Huang
Recruiting

Effects of a 12-week Supervised Exercise Program Post Bariatric Surgery on Body Composition, Muscle Strength, and Insulin Resistance

June 16, 2026

Conditions: Bariatric Surgery; Exercise; Body Composition Changes
Interventions: Other: 12-week supervised exercise program
Sponsors: Laval University
Completed

Exploratory Study on Toripalimab and Anlotinib Combined With Standard Chemotherapy for Refractory Dermatofibrosarcoma Protuberans

June 16, 2026

Conditions: Dermatofibrosarcoma Protuberans (DFSP)
Interventions: Drug: Toripalimab; Drug: Anlotinib; Drug: Standard Chemotherapy
Sponsors: Yanjie Zhang, MD
Not yet recruiting

AI for Rare Disease Diagnosis in Real World

June 16, 2026

Conditions: Rare Disorders; Rare Diseases
Interventions: Other: AI system
Sponsors: Peking Union Medical College Hospital; Cangzhou Central Hospital; Zhangzhou Municipal Hospital; Dongguan People's Hospital; First People's Hospital of Foshan; Tibet Autonomous Region People's Hospital; Guizhou Provincial People's Hospital; Tianjin Children's Hospital; The First People's Hospital of Yunnan; Qinghai People's Hospital
Not yet recruiting

Survival After Cardiac Arrest: How New Treatment Guidelines Changed Patient Outcomes.

June 16, 2026

Conditions: Cardiac Arrest (CA); Post Cardiac Arrest Syndrome
Interventions: Other: post-resuscitation care
Sponsors: Azienda Sanitaria Universitaria Integrata del Trentino
Completed

Tissue Modeling in Systemic Sclerosis Using Induced Pluripotent Stem Cells (iPSCs)

June 16, 2026

Conditions: Systemic Sclerosis (SSc)
Interventions: Procedure: Blood Sample Collection
Sponsors: University Hospital, Montpellier
Not yet recruiting

Impact of Propranolol on the Prognosis of Patients With Decompensated Cirrhosis and MELD Score > 9

June 16, 2026

Conditions: Cirrhosis
Interventions: Other: conventional therapy; Drug: propranolol
Sponsors: General Hospital of Shenyang Military Region
Not yet recruiting

Mathematical Modeling of Blood Sugar and Hormone Responses in Insulin-Dependent Type 2 Diabetes

June 16, 2026

Conditions: Type 2 Diabetes; Insulin Dependent Diabetes
Sponsors: Clinical Nutrition Research Center, Illinois Institute of Technology
Recruiting

A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough - China Extension

June 16, 2026

Conditions: Refractory Chronic Cough
Interventions: Drug: BLU-5937; Drug: Placebo
Sponsors: GlaxoSmithKline
Recruiting

Clinical Trial of the Efficacy and Safety of Raphamin in the Treatment of Acute Bronchitis in Adult Patients

June 16, 2026

Conditions: Bronchitis; Acute Bronchitis
Interventions: Drug: Raphamin; Drug: Placebo
Sponsors: Materia Medica Holding
Recruiting

Optimized Novel Wireless Assessment of Respiratory and Circulatory Dirstress - Alarm Validation

June 16, 2026

Conditions: Postoperative Care; Deterioration, Clinical
Interventions: Device: Continuous vital sign monitoring
Sponsors: Eske Kvanner Aasvang; Rigshospitalet, Denmark; University Hospital Bispebjerg and Frederiksberg
Not yet recruiting

Initial Study of a MOTHER-DAUGHTER SIDE-BRANCH ACCESS™ DES System (FIH EFS)

June 16, 2026

Conditions: Coronary Angioplasty; Bifurcation Coronary Artery Disease; Ischemic Heart Disease (IHD); Percutaneous Coronary Intervention (PCI)
Interventions: Device: MD-SBA DES System
Sponsors: Advanced Bifurcation Systems Inc.
Active, not recruiting

Wearable Technology in Heart Failure Patients

June 16, 2026

Conditions: Heart Failure
Sponsors: The Cleveland Clinic
Recruiting

Static Stretching Reshapes Post-RT Recovery

June 16, 2026

Conditions: Healthy; Healthy Subjects (HS); Cardiovascular Adaption; Stretching; Recovery Outcomes
Interventions: Other: Resistance Training; Other: Resistance training + Static Stretching
Sponsors: University of Palermo
Completed

Globe Registry: Globe® Pulsed Field System Registry Study for Treating Patients With Symptomatic Atrial Fibrillation

June 16, 2026

Conditions: Atrial Fibrillation
Interventions: Device: Globe Pulsed Field System
Sponsors: Kardium Inc.
Not yet recruiting

Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

June 16, 2026

Conditions: Myocardial Injury; Coronary Artery Disease
Interventions: Diagnostic Test: High-Sensitivity Troponin; Diagnostic Test: Cardiac MRI
Sponsors: Second Hospital of Jilin University
Not yet recruiting

Remimazolam Versus Dexmedetomidine for Sedation During Neuraxial

June 16, 2026

Conditions: Pregnant People; Anxiety
Interventions: Drug: Remimazolam; Drug: Dexmedetomidine
Sponsors: Icahn School of Medicine at Mount Sinai
Not yet recruiting

Rocuronium and Fentanyl for Neonatal Intubation: A Randomized Clinical Trial (NEORIN)

June 16, 2026

Conditions: Infant, Premature; Intubation, Intratracheal; Respiratory Distress Syndrome, Newborn; Apnea of Prematurity
Interventions: Drug: Rocuronium Bromide 10 MG/ML; Drug: Fentanyl 1 mcg/kg IV, single dose, administered before non-emergent tracheal intubation.
Sponsors: UEA - Universidade Do Estado Do Amazonas
Not yet recruiting

Intraseptal and Periodontal Ligament Anaesthesia for Tooth Extraction in Patients With Type 2 Diabetes

June 16, 2026

Conditions: Diabetes Mellitus Type 2
Interventions: Procedure: Intraseptal anaesthesia (ISA); Procedure: Periodontal ligament anaesthesia (PLA)
Sponsors: University of Business Academy in Novi Sad, Serbia
Completed

Biomarkers in Alzheimer's and Parkinson's Diseases for IA

June 16, 2026

Conditions: Parkinson Disease; Alzheimer Disease; Mild Cognitive Impairment; Dementia
Interventions: Diagnostic Test: Neuropsycological assesment; Radiation: cerebral MRI; Other: EEG; Biological: Venous blood sample of 20ml; Biological: Sample collection of exfoliated buccal mucosa; Device: Telemonitoring at home for 1 week
Sponsors: IRCCS San Raffaele Roma; University of Roma La Sapienza; Azienda Ospedaliera di Padova; Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Active, not recruiting

Evaluation of Calcified Coronary Lesion Preparation With the Naviscore Scoring Balloon

June 16, 2026

Conditions: Coronary Arterial Disease (CAD); Calcific Coronary Arteriosclerosis
Interventions: Device: Scoring Balloon PTCA Catheter; Device: Non-Compliant (NC) Angioplasty Balloon
Sponsors: University of Mons; iVascular S.L.U.
Not yet recruiting

Effects of a Physical Rehabilitation Program on Long COVID

June 16, 2026

Conditions: Long Covid
Interventions: Other: Physical rehabilitation; Device: Treadmill ergometer; Device: Pulley
Sponsors: Universidade do Estado do Pará
Completed

Comparison of Tunneled Cuffed Dialysis Catheters Versus Arteriovenous Fistulae in Elderly or Multimorbid Patients

June 16, 2026

Conditions: End Stage Renal Failure, Hemodialysis; Vascular Access; Fistulas Arteriovenous; Haemodialysis Complication; Haemodialysis Patients
Interventions: Device: Tunneled cuffed catheter (TCC) will be implanted for chronic haemodialysis treatment; Procedure: Arteriovenous fistula creation for chronic haemodialysis treatment
Sponsors: Medical University of Vienna
Not yet recruiting

Treadmill Aerobic Training and Quality of Life in Anemic Females

June 16, 2026

Conditions: Iron Deficiency Anemia Treatment; Iron Deficiency Anemia (IDA)
Interventions: Behavioral: Treadmill Aerobic Exercise; Other: Standard Medical Care and Nutritional Protocol
Sponsors: Cairo University; Horus University
Completed

Bilevel Erector Spinae Plane Block Versus Pectoserratus Block for Analgesia in Modified Radical Mastectomy

June 16, 2026

Conditions: Breast Cancer
Interventions: Procedure: Ultrasound guided bilevel Erector spinae plane block (ESPB); Procedure: Ultrasound guided Pectoserratus Block
Sponsors: National Cancer Institute, Egypt
Recruiting

The Clinical Outcomes and Therapeutic Effects in Patients With Cardiac Implantable Electronic Device-detected Subclinical and Clinical Atrial Fibrillation.

June 16, 2026

Conditions: Subclinical Atrial Fibrillation; Cardiac Arrhythmias
Interventions: Other: Early Rhythm Control Strategy; Other: Usual Care
Sponsors: National Taiwan University Hospital
Recruiting

Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest

June 16, 2026

Conditions: Heart Arrest, Out-Of-Hospital; Defibrillators
Interventions: Behavioral: AED training adjunct
Sponsors: Wayne State University; Oregon Health and Science University; American Heart Association
Not yet recruiting

Barriers and Facilitators to Psychosocial Management in Cardiac Rehabilitation at the South Francilien Hospital Center (CHSF)

June 16, 2026

Conditions: Cardiac Rehabilitation
Interventions: Other: Self administered questionnaire of cardiac rehabilitation staff members; Other: Self administered questionnaire of cardiac rehabilitation patients; Other: Self administered questionnaire of occupational health physicians
Sponsors: Centre Hospitalier Sud Francilien
Not yet recruiting

Prevalence of Cardiac Thrombi in Cardiac Amyloidosis

June 16, 2026

Conditions: Cardiac Amyloidosis
Interventions: Procedure: Cardiac CT scan with contrast
Sponsors: Centre Hospitalier Universitaire Dijon
Not yet recruiting

Human Observatory Study

June 15, 2026

Conditions: Aging; Mortality; All-cause Mortality; Life Expectancy; Cardiovascular Diseases; Neoplasms; Cognitive Dysfunction; Metabolic Syndrome; Frailty; Musculoskeletal Disease; Neurodegenerative Disease; Dementia; Activities of Daily Living; Health Related Quality of Life; Disability Physical; Environmental Exposure; Occupational Diseases; Health Equity; Social Determinants of Health
Interventions: Other: Multi-Domain Ecological and Clinical Data Linkage
Sponsors: Longevity Metrics, Inc.
Recruiting

A Phase II Study to Evaluate the Efficacy and Safety of ENERGI-F705 Tablets for Parkinson's Disease

June 15, 2026

Conditions: Parkinson's Disease (PD)
Interventions: Drug: ENERGI-F705 Tablets; Drug: Placebo tablets
Sponsors: Energenesis Biomedical Co., Ltd.
Not yet recruiting

Exclusion of Left Atrial Appendage Thrombus in Emergency Department Patients With Atrial Fibrillation Undergoing CT to Assess for Pulmonary Embolus: A Feasibility Study

June 15, 2026

Conditions: Atrial Fibrillation (AF); Pulmonary Embolism (PE); Left Atrial Appendage Thrombosis
Interventions: Device: Delayed Un-gated CT Scan for Left Atrial Appendage Thrombus; Device: Delayed Gated CT Scan for Left Atrial Appendage Thrombus
Sponsors: Northwell Health; Canon Medical Systems, USA
Not yet recruiting

Meditation as a Stress Management Strategy in Cardiac Rehabilitation for Coronary Artery Disease Patients: A Pilot Randomized Controlled Trial

June 15, 2026

Conditions: Coronary Artery Disease; Stress; Anxiety
Interventions: Other: Meditation Program; Other: Exercise-based Cardiac Rehabilitation (standard)
Sponsors: Universidad Rey Juan Carlos
Completed

Risk Stratification and Prognostic Value of Right Ventricular Dysfunction Screening Using Transthoracic Echocardiography in Acute Pulmonary Embolism

June 15, 2026

Conditions: Pulmonary Embolism
Interventions: Other: Transthoracic Echocardiography
Sponsors: Sohag University
Recruiting

Association Between Circulating BDNF Levels and Atrial Cardiomyopathy in Patients Undergoing Ablation for Persistent Atrial Fibrillation

June 15, 2026

Conditions: Atrial Fibrillation (AF); Cardiac Arrhythmia; Atrial Fibrillation Ablation; BDNF; Atrial Cardiomyopathy
Interventions: Biological: blood draw; Procedure: CT scan
Sponsors: Centre Hospitalier Universitaire Dijon
Not yet recruiting

Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors

June 15, 2026

Conditions: Locally Advanced Gastrointestinal Stromal Tumor; Metastatic Gastrointestinal Stromal Tumor; Recurrent Gastrointestinal Stromal Tumor; Refractory Malignant Gastrointestinal Stromal Tumor; Unresectable Malignant Gastrointestinal Stromal Tumor
Interventions: Biological: Aldesleukin; Procedure: Biospecimen Collection; Procedure: Chest Radiography; Procedure: Computed Tomography; Drug: Cyclophosphamide; Procedure: Echocardiography Test; Biological: Filgrastim; Drug: Fludarabine; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography; Procedure: Surgical Procedure; Biological: Tumor Infiltrating Lymphocyte Therapy
Sponsors: Joal Beane
Not yet recruiting

Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults

June 15, 2026

Conditions: Hypertension; Elevated Blood Pressure
Interventions: Other: Zona Plus 4-Week Isometric Handgrip Exercise Intervention; Other: Squegg 4-Week Isometric Handgrip Exercise Intervention
Sponsors: McMaster University
Not yet recruiting

Observational Study of Natural History of BAG3 Gene Mutation-Associated Dilated Cardiomyopathy in Chinese Adults

June 15, 2026

Conditions: Dilated Cardiomyopathy
Interventions: Other: Observational, None intervention
Sponsors: AstraZeneca
Not yet recruiting

Evaluation of the Safety and Effectiveness of CHORDS® Cerebral Protection System During TAVR: DUET Trial

June 15, 2026

Conditions: Transcatheter Aortic Valve Replacement (TAVR); Cerebral Vascular Accident (CVA)/Stroke
Interventions: Device: CHORDS® Cerebral Protection System; Device: Sentinel Cerebral Protection System
Sponsors: Resonova (Shanghai) Medtech Limited
Recruiting

Prospective Evaluation of Flare Detection in IBD With Digital Biomarkers: Bring Your Own Device Study

June 15, 2026

Conditions: Inflammatory Bowel Disease (IBD); Ulcerative Colitis (UC); Crohn Disease (CD)
Interventions: Device: Wearing their own wearable device.
Sponsors: Maastricht University Medical Center; Maastricht University; TNO; Franciscus Gasthuis & Vlietland (Hospital); Jeroen Bosch Ziekenhuis, s'-Hertogenbosch
Not yet recruiting

A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension

June 15, 2026

Conditions: Hypertension
Interventions: Drug: NS-0200 (low sildenafil); Drug: NS-0200 (higher sildenafil); Other: Placebo
Sponsors: NuSirt Biopharma; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Influence of Cardiopulmonary Rehabilitation on Cardiorespiratory Adaptation in Patients With Pulmonary Hypertension

June 15, 2026

Conditions: Pulmonary Hypertension Due to Lung Disease (Disorder)
Interventions: Behavioral: cardiopulmonary rehabilitation in the form of moderate-intensity interval aerobic training; Device: Inspiratory Muscle Training; Other: Medical treatment
Sponsors: Cairo University
Not yet recruiting

Breathwork Training Reduces Anxiety In Outpatient Gastrointestinal Procedures

June 15, 2026

Conditions: Anxiety
Interventions: Behavioral: paced breathwork
Sponsors: Calm and Sense Technologies LLC
Completed

Interventional Study on the Effects of Forest Therapy in Fibromyalgia Patients

June 15, 2026

Conditions: Fybromyalgia; Fibromyalgia (FM)
Interventions: Behavioral: Forest therapy
Sponsors: Azienda USL Toscana Nord Ovest
Not yet recruiting

To Evaluate the Safety and Tolerability of Anti-Human CD70 T-Cell Injection in Subjects With Advanced/Metastatic Renal Cancer

June 15, 2026

Conditions: Renal Cell Carcinoma (RCC)
Interventions: Drug: Anti-Human CD70 T-Cell Injection
Sponsors: Hrain Biotechnology Co., Ltd.; RenJi Hospital
Not yet recruiting

Breathlessness Perceptions Within Respiratory Diseases

June 15, 2026

Conditions: Chronic Obstructive Pulmonary Disease (COPD); Asthma (Diagnosis); Interstitial Lung Disease (ILD); Bronchiectasis; Breathing Pattern Disorder
Sponsors: University Hospitals, Leicester
Recruiting

Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Fracture Surgery

June 15, 2026

Conditions: Older Adults; Hip Fracture Surgery; Fascia Iliaca Block; Liposomal Bupivacaine; Postoperative Pain
Interventions: Drug: Liposomal bupivacaine (LB); Drug: Plain bupivacaine
Sponsors: Peking University First Hospital
Not yet recruiting

HeartR™ PDA Occluder Post-Market Follow-Up Study

June 15, 2026

Conditions: Patent Ductus Arteriosus
Interventions: Device: HeartR™ PDA Occluder
Sponsors: Lifetech Scientific (Shenzhen) Co., Ltd.
Recruiting

Intravenous Iron to Improve Symptoms, Quality of Life and Exercise Capacity in HFpEF With Iron Deficiency

June 15, 2026

Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF
Interventions: Drug: Ferric Derisomaltose; Drug: Placebo
Sponsors: Government of Jersey; University of Oxford
Not yet recruiting

A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

June 12, 2026

Conditions: Asthma
Interventions: Drug: HFA-152a; Drug: HFA-134a
Sponsors: GlaxoSmithKline
Not yet recruiting

Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy

June 12, 2026

Conditions: Carpal Tunnel; Transthyretin Amyloidosis
Interventions: Diagnostic Test: Annular ligament biopsy
Sponsors: Clinique Saint Jean, France
Recruiting

Trans-nasal Sphenopalatine Ganglion Block for Prevention of Emergence Agitation Following Functional Endoscopic Sinus Surgery

June 12, 2026

Conditions: Chronic Rhinosinusitis (CRS); Emergence Agitation
Interventions: Procedure: Bilateral Trans-nasal Sphenopalatine Ganglion Block; Procedure: Sham Trans-nasal Injection
Sponsors: Mansoura University
Completed

Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus

June 12, 2026

Conditions: Gestational Diabetes
Interventions: Other: GRP 1 Tab metformin; Other: GRP 2 Inj insulin; Other: GRP 3 Tab metformin + HI flora sachet; Other: GRP 4 Inj insulin + HI flora sachet
Sponsors: Riphah International University
Not yet recruiting

Fermented Foods and Bone Health: Investigating the Gut-Bone Axis in Premenopausal Vegan Women

June 12, 2026

Conditions: Bone; Bone Health
Interventions: Other: Fermented Plant-Based Foods; Other: Non-Fermented Plant-Based Foods
Sponsors: Isabelle Herter-Aeberli; Swiss National Science Foundation; Philhuman Foundation; Czech Science Foundation; Charles University, Czech Republic
Not yet recruiting

AI-powered ECG Analysis for Deadly Arrhythmias and ICI Myocarditis

June 12, 2026

Conditions: Arrhythmia; Long QT Syndrome; Immune Checkpoint Inhibitor-Related Myocarditis
Sponsors: Groupe Hospitalier Pitie-Salpetriere; Institut de Recherche pour le Developpement; Institut National de la Santé Et de la Recherche Médicale, France; Vanderbilt University Medical Center; University of California, San Francisco; University Hospital, Bordeaux; Assistance Publique - Hôpitaux de Paris; Banook Group
Recruiting

FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

June 12, 2026

Conditions: Acute Myeloid Leukemia
Interventions: Drug: Autologous HLA-A*02:01-restricted CD4+/CD8+ Anti-WT1 TCR/CD8ab-expressing T-cells; Drug: Azacitidine; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Chest Radiography; Procedure: Computed Tomography; Procedure: Echocardiography Test; Procedure: Lumbar Puncture; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography
Sponsors: Fred Hutchinson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting

The Impact of Physical Exercise on Working Memory in Elderly People With Mild Cognitive Impairment

June 12, 2026

Conditions: Mild Cognitive Impairment
Interventions: Behavioral: Resistance band exercise intervention; Behavioral: Brisk walking intervention; Behavioral: Eight-Section brocade exercise intervention; Behavioral: Control
Sponsors: Shanghai University of Sport
Enrolling by invitation

Comparison of Chest Compressions Performed With the Lower Limb and the Classical Method (Lower_limb_CPR).

June 12, 2026

Conditions: Cardiac Arrest
Interventions: Other: Instruction to perform chest compressions using the lower limb (foot)
Sponsors: Marcin Muża; Powiślańska Academy of Applied Sciences
Completed

Effects of Chronic Non-invasive Vagus Nerve Stimulation in an Asplenic Individual Suffering From Rheumatoid Arthritis

June 12, 2026

Conditions: Rheumatoid Arthritis (RA
Interventions: Device: Trans-auricular vagus nerve stimulation
Sponsors: Osteoflow Health Clinic
Completed

The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment

June 12, 2026

Conditions: Pregnant Individuals; Aneuploidy; Down Syndrome (Trisomy 21); 22q11.2 Deletion Syndrome; Trisomy 13; Trisomy 18; Sex Chromosome Abnormalities
Sponsors: BillionToOne Inc.
Recruiting

Combined Arm-leg Ergometer Endurance Training Versus Cycle Ergometer Endurance Training in Myocardial Infarction

June 12, 2026

Conditions: Post Myocardial Infarction
Interventions: Device: arm-leg ergometer training; Device: traditional cycle ergometer training
Sponsors: Riphah International University
Not yet recruiting

Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction

June 12, 2026

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: Other: Extra-virgin olive oil
Sponsors: Old Dominion University
Not yet recruiting

OPN Balloon for SAFE Recanalization of Calcified Coronary Lesions

June 12, 2026

Conditions: Coronary Arterial Disease (CAD); In Stent Restenosis; Calcified Coronary Lesions
Interventions: Device: non compliant balloon
Sponsors: Minneapolis Heart Institute Foundation
Not yet recruiting

HJB647 Phase 1b Study in Japanese Healthy Participants With Elevated Blood Pressure and Patients With Hypertension

June 12, 2026

Conditions: Elevated Blood Pressure; Hypertension
Interventions: Drug: HJB647; Drug: Placebo
Sponsors: Novartis Pharmaceuticals
Not yet recruiting

Digital Lifestyle Coaching for Alzheimer's Disease Prevention in APOE4 Carriers

June 12, 2026

Conditions: Mild Cognitive Impairment (MCI); Alzheimer Disease (AD)
Interventions: Behavioral: Education
Sponsors: Scripps Translational Science Institute; Sapient Bioanalytics; TEAL Rise; 23andMe, Inc.; Alamar Biosciences; Oura Ring, Inc
Not yet recruiting

VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU

June 12, 2026

Conditions: Respiration, Artificial; Positive-Pressure Respiration; Postoperative Complications (Cardiopulmonary); Postoperative Complications; Critical Illness; Intensive Care Units
Sponsors: Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva; Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Not yet recruiting

Transcranial Doppler in Preeclampsia and Its Complications.

June 12, 2026

Conditions: Pre Eclampsia
Interventions: Diagnostic Test: Transcranial doppler ultrasound
Sponsors: University Tunis El Manar
Completed

STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump

June 12, 2026

Conditions: LVAD (Left Ventricular Assist Device) Thrombosis; LVAD; LVAD (Left Ventricular Assist Device); LVAD-related GI Bleed; Bleeding; Thrombosis; Stroke; Hemocompatibility-related Adverse Event; Ventricular Assist Device; Aspirin; Antiplatelet Therapy; Antithrombotic Therapy
Interventions: Drug: Warfarin (INR 2-3) with placebo; Drug: Warfarin (INR 2-3) with aspirin
Sponsors: China National Center for Cardiovascular Diseases; Beijing Anzhen Hospital; Wuhan Asia Heart Hospital; Shanghai Zhongshan Hospital; Jiangsu Provincial People's Hospital; Second Hospital of Jilin University; Nanjing First Hospital, Nanjing Medical University; Zhejiang Provincial People's Hospital; Sir Run Run Shaw Hospital; Sichuan Provincial People's Hospital; First Affiliated Hospital Xi'an Jiaotong University; Zhejiang University; First Affiliated Hospital of Xinjiang Medical University; Fuwai Yunnan Cardiovascular Hospital; Guangdong Provincial People's Hospital; Henan Provincial Chest Hospital; Fujian Provincial Hospital; People's Hospital of Xinjiang Uygur Autonomous Region; Union hospital of Fujian Medical University; Ruijin Hospital; The 7th People's Hospital of Zhengzhou; Chinese Academy of Medical Sciences, Fuwai Hospital; Xijing Hospital
Not yet recruiting

Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia

June 12, 2026

Conditions: Fibromyalgia (FM)
Interventions: Device: Primary Motor Cortex Stimulation; Device: Occipital Lobe Stimulation
Sponsors: Pulkit Grover; Department of Anesthesiology & Perioperative Medicine, University of Pittsburgh; University of Pittsburgh Clinical and Translational Science Institute (CTSI)
Not yet recruiting

Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.

June 12, 2026

Conditions: Influenza; Acute Respiratory Viral Infections
Interventions: Drug: Ingavirin forte, capsules, 90 mg + 20 mg; Drug: Ingavirin, capsules, 90 mg
Sponsors: Valenta Pharm JSC
Recruiting

Circadian-Synchronized Breast Milk Feeding and Sleep in Preterm Infants: A Multicenter Randomized Controlled Trial

June 12, 2026

Conditions: Preterm Infant; Sleep
Interventions: Behavioral: Circadian-Synchronized Breast Milk Feeding; Behavioral: Routine Breast Milk Feeding
Sponsors: Shanghai Jiao Tong University School of Medicine
Not yet recruiting