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ClinicalTrials.gov: Other terms: heart disease | First posted in the last 14 days

Studies found on ClinicalTrials.gov by a search of: Other terms: heart disease | First posted in the last 14 days

Turkish APA5 Validity Reliability

September 18, 2026

Conditions: Postoperative Care; Pain; Nursing Care
Sponsors: Namik Kemal University
Completed

Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening Ischemia

September 18, 2026

Conditions: Chronic Limb-Threatening Ischemia; Diabetic Foot Ulcer; Infrapopliteal Arterial Occlusive Disease
Interventions: Procedure: Lower-Extremity Revascularization; Genetic: Donaperminogene Seltoplasmid
Sponsors: First Affiliated Hospital of Wenzhou Medical University; Beijing Northland Biotech. Co., Ltd.
Not yet recruiting

Gemini Flash 3.6 Versus Human Observers for FIGO-Based Interpretation of Intrapartum Cardiotocography

September 18, 2026

Conditions: Fetal Hypoxia; Fetal Distress; Low Apgar Score; Neonatal Acidemia
Sponsors: Assiut University
Not yet recruiting

ECG-based AI Screening for Cases of Undiagnosed Moderate-to-Severe Aortic Stenosis in the Primary Care Setting

September 18, 2026

Conditions: Aortic Stenosis
Interventions: Device: AK-AVS
Sponsors: AccurKardia, Inc.
Enrolling by invitation

Sparrow App Guided Evaluation (SAGE) Vanguard Trial for Aortic Stenosis in Adults Aged Seventy and Older

September 18, 2026

Conditions: Moderate or Severe Aortic Stenosis
Interventions: Device: Stethophone
Sponsors: Sunnybrook Health Sciences Centre; KMH Cardiology and Diagnostic Centres; Sparrow Acoustics Inc.; Ontario Health; Canadian Cardiovascular Society; Edwards life sciences; Medtronic
Not yet recruiting

COMpulsive Gambling: Efficacy of DEEP Transcranial Magnetic Stimulation With H7 COIL

September 18, 2026

Conditions: Gambling Disorder
Interventions: Device: active r-TMS; Device: Sham (No Treatment)
Sponsors: Sveti Ivan Psychiatric Hospital
Not yet recruiting

The BRAVE (Behaviourally Responsive Assessments of Vital Signs in Emergency) Study

September 18, 2026

Conditions: Autism Spectrum Disorder
Interventions: Device: wearable vital sign device
Sponsors: Hamilton Health Sciences Corporation
Not yet recruiting

Utilization of Guided Point of Care Ultrasound in Heart Failure Diagnosis Pilot Trial

September 18, 2026

Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: Device: Point of Care Ultrasound
Sponsors: Corewell Health West; Michigan State University
Not yet recruiting

Utility of the Perclose ProGlide™ Suture-Mediated Closure Device After Cardiologic Procedures Via the Femoral Vein Approach (Eight-Clover)

September 18, 2026

Conditions: Atrial Fibrillation; Atrial Septal Defect; Vascular Closure Device
Interventions: Device: Perclose ProStyle™ Suture-Mediated Closure System; Other: Conventional Hemostasis (Manual Compression or Figure-of-Eight Suture)
Sponsors: Ewha Womans University Mokdong Hospital; Ewha Womans University Seoul Hospital
Enrolling by invitation

Assessment of Changes in Autonomy Through Analysis of Smartphone Usage Data in Patients With Alzheimer's Disease

September 18, 2026

Conditions: Alzheimer Disease (AD)
Interventions: Other: Data collection; Other: Neuropsychological assesment; Other: Autonomy questionnaire
Sponsors: Poitiers University Hospital
Not yet recruiting

The Effect of Using the Popit Toy and Stress Ball During Inhaler Therapy in Children

September 18, 2026

Conditions: Non-Pharmacological Interventions; NEBULIZATION
Interventions: Behavioral: Intervention 1 Popit toy; Behavioral: Intervention 2 Stress ball
Sponsors: Izmir Katip Celebi University
Completed

The GranStone Trial

September 18, 2026

Conditions: Paraffinoma; Granuloma, Foreign-Body
Interventions: Drug: empagliflozin (Jardiance) 25 mg; Drug: Losartan 100 mg
Sponsors: Martin Blomberg Jensen; Copenhagen University Hospital at Herlev
Not yet recruiting

Combining Moderate Aerobic Exercise With Inspiratory Muscle Training for Dialysis Patients With Atrial

September 18, 2026

Conditions: Atrial Fibrillation (AF)
Interventions: Device: inspiratoy muscle training; Device: Aerobic exercise +inspiratory muscle training
Sponsors: Beni-Suef University
Not yet recruiting

Transcutaneous Auricular Vagus Nerve Stimulation for Reducing Postoperative Hypoxemia

September 18, 2026

Conditions: Hypoxemia
Interventions: Device: Transcutaneous Auricular Vagus Nerve Stimulator
Sponsors: Affiliated Hospital of Nantong University
Not yet recruiting

Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults

September 18, 2026

Conditions: Cardiorespiratory Fitness; Metabolic Health; Cardiac Function; Pulmonary Function; Exercise Test
Interventions: Diagnostic Test: Cardiopulmonary Exercise Test; Diagnostic Test: Incremental Step Test
Sponsors: Heriot-Watt University
Enrolling by invitation

Stress Management Among Nurses and Midwives in Inpatient Care

September 18, 2026

Conditions: The Study Compares HRV Biofeedback and Eurythmy Therapy as Stress Management Interventions in Female Hospital Nurses and Midwives
Interventions: Behavioral: HRV Biofeedback; Behavioral: Behavioral - Eurythmy Therapy (EYT)
Sponsors: ARCIM Institute Academic Research in Complementary and Integrative Medicine; Die Filderklinik, Filderstadt, Germany; University of Wuerzburg
Completed

Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age

September 18, 2026

Conditions: Skin Ageing; Healthy Ageing; Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults; Longevity; Healthspan Improvement; Cognitive Processing Speed; Hair Aging; Recovery; Sleep; Biological Ageing; BIOLOGICAL CLOCKS; Biological Aging Marker
Interventions: Dietary Supplement: Advanced ID; Dietary Supplement: Placebo Control
Sponsors: IDI Skincare Limited; University of Dublin, Trinity College; University of Edinburgh
Active, not recruiting

SPIKE FLOW Endocardial Lead Safety and Performance Study

September 18, 2026

Conditions: Acute Myocardial Infarction (AMI); Asystole; Bradycardia; AV Block; Ventricular Tachyarrhythmia
Interventions: Procedure: Lead insertion; Procedure: lead removal
Sponsors: FIAB SpA
Recruiting

NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke

September 18, 2026

Conditions: Stroke; Stroke, Acute Ischemic; Stroke, Ischemic; Stroke, Cryptogenic; Stroke, Cardiovascular
Interventions: Drug: MLC901; Other: Standard treatment for acute ischemic stroke
Sponsors: EVD Pharmacy and Medical Company Limited
Recruiting

Clinical Outcomes of Primary Cementless Total Hip Arthroplasty Using the Collarless Actis Stem

September 18, 2026

Conditions: Osteoarthritis, Hip; Femur Head Necrosis; Femoral Neck Fractures; Arthritis Rheumatoid; Developmental Dysplasia of Hip; Arthritis, Post-traumatic
Interventions: Device: Collarless Actis femoral stem
Sponsors: Seoul National University Bundang Hospital; Johnson & Johnson Medical Korea Ltd
Recruiting

Georgia CEAL RESTORES Family Diabetes Study

September 18, 2026

Conditions: Weight Reduction; Prediabetes
Interventions: Behavioral: Family Diabetes Prevention
Sponsors: Morehouse School of Medicine; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices

September 18, 2026

Conditions: Hypertrophic Cardiomyopathy; Left Ventricular Outflow Obstruction; Systolic Anterior Motion
Interventions: Device: SESAME Procedure
Sponsors: National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Analysis of Life-threatening ARrhythMias After Acute Coronary Syndrome

September 17, 2026

Conditions: Acute Coronary Syndromes (ACS); Ventricular Tachycardia (VT); Ventricular Fibrillation; Pulseless Electrical Activity; Asystole; Cardiac Arrest (CA); Myocardial Infarction (MI); Non-ST Elevation (NSTEMI) Myocardial Infarction; ST Elevation (STEMI) Myocardial Infarction; Unstable Angina (UA)
Sponsors: Catharina Ziekenhuis Eindhoven; Anna Ziekenhuis Geldrop; St.Jans Gasthuis Weert
Recruiting

Effect of Atogepant on the Vestibulo-Ocular Reflex in Healthy Adults and Adults With Migraine

September 17, 2026

Conditions: Migraine Disorders, Brain; Healthy Adult Participants; Vestibulo-Ocular Reflex
Interventions: Drug: Atogepant 60 mg; Drug: Placebo
Sponsors: Konrad Peter Weber
Not yet recruiting

TORCH-LATAM-004: Regional Advanced-Therapy Pathways for Adults With Acquired or Structural Heart Disease

September 17, 2026

Conditions: Advanced Heart Failure; Acquired Heart Disease; Structural Heart Disease; Heart Transplantation; Mechanical Circulatory Support
Interventions: Other: TORCH Adult Advanced Therapies Pathway (TORCH-AATP)
Sponsors: CardioVision International Tech, S.A.S. de C.V.; Advanced Sciences Technologies, S.A. de C.V.; Advanced Science Technologies S.A.S.
Not yet recruiting

Telerehabilitation in Patients With Peripheral Arterial Disease

September 17, 2026

Conditions: Peripheral Arterial Disease
Interventions: Behavioral: Home-based telerehabilitation
Sponsors: Grigore T. Popa University of Medicine and Pharmacy
Completed

Branching Scenario-Based Education in Coronary Artery Disease

September 17, 2026

Conditions: Coronary Arterial Disease (CAD)
Interventions: Behavioral: Virtual Reality-Based Branching Scenario Education; Behavioral: Tablet-Based Branching Scenario Education
Sponsors: Abant Izzet Baysal University
Not yet recruiting

Warfarin Quality, Adherence, Range, Determinants, and Events in Egyptian Rheumatic Heart Disease and Atrial Fibrillation

September 17, 2026

Conditions: AF
Interventions: Diagnostic Test: INR; Diagnostic Test: Time in Therapeutic Range; Diagnostic Test: International Normalized Ratio (INR)
Sponsors: Assiut University
Not yet recruiting

Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)

September 17, 2026

Conditions: Hemodynamic Response
Interventions: Drug: Saline (0.9% NaCl); Drug: Dexmedetomidine; Drug: Remifentanil
Sponsors: Inonu University
Not yet recruiting

A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/Procedures

September 17, 2026

Conditions: Frailty; Thoracic Surgery
Interventions: Behavioral: Frailty-specific prehabilitation program; Behavioral: A sham stretching exercise intervention
Sponsors: The University of Hong Kong
Recruiting

Analgesic Efficacy of Peritonsillar Ropivacaine Infiltration After Tonsillectomy in Children

September 17, 2026

Conditions: Tonsillectomy; Ropivacaine; Analgesia; Local Anesthesia; Children
Interventions: Other: Peritonsillar infiltration with ropivacaine; Other: Peritonsillar infiltration with normal saline; Drug: Normal Saline; Drug: ropivacaine (local infiltration)
Sponsors: University Hospital, Mahdia
Completed

A Phase II Study of HS-20093 Injection Combined With Adebrelimab Versus HS-20093 Injection in Previously Treated Patients With Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations

September 17, 2026

Conditions: Non-Small Cell Lung Cancer
Interventions: Drug: HS-20093 for Injection; Drug: Adebrelimab Injection
Sponsors: Hansoh BioMedical R&D Company
Not yet recruiting

Effect of Mindful Breathing in Patient With Heart Failure:

September 17, 2026

Conditions: Heart Failure; Nursing Care; Symptom Management; Mindful Breathing Meditation
Interventions: Other: Mindful Breathing
Sponsors: Ankara Medipol University
Completed

Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic Shock

September 17, 2026

Conditions: Cardiogenic Shock; Acute Myocardial Infarction; Acute Decompensated Heart Failure
Interventions: Device: NIRSense Tissue Oximetry Sensor System
Sponsors: NIRSense Inc.; Cleveland Clinic Florida
Recruiting

Effects of Whole-Body Electromyostimulation in Overweight/Obese Postmenopausal Women

September 17, 2026

Conditions: Cardiometabolic Health in Overweight/Obese Postmenopausal Women
Interventions: Other: Whole-body electromyostimulation (WB-EMS) training; Behavioral: Supervised exercise without whole-body electromyostimulation (WB-EMS)
Sponsors: High Institute of Sports and Physical Education of Kef
Not yet recruiting

Development and Clinical Validation of a Smart Analysis System for a Wearable Cardiac Ultrasound Device

September 17, 2026

Conditions: Cardiovascular Diseases
Interventions: Device: Wearable Cardiac Ultrasound System
Sponsors: Kunjing Pang
Not yet recruiting

Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary Syndrome

September 17, 2026

Conditions: Acute Coronary Syndromes; Dyslipidemia
Interventions: Drug: bempedoic acid; Drug: Ezetimibe; Drug: High-Intensity Statin Therapy
Sponsors: Taipei Medical University Hospital
Recruiting

Hand Position, CPR Quality and Rescuer Comfort

September 17, 2026

Conditions: Cardiac Arrest (CA)
Interventions: Behavioral: Interlocked-finger chest compression technique; Behavioral: Overlapped hands chest compression technique
Sponsors: University of Pecs
Recruiting

The Role Oral Microbiome in the Development and Progression of Aorta Aneurysm and Carotid Atherosclerosis

September 17, 2026

Conditions: Aorta Aneurysm; Carotid Arteriosclerosis
Sponsors: Semmelweis University
Enrolling by invitation

Dapagliflozin and Right Heart Recovery After ASD Device Closure

September 17, 2026

Conditions: ASD2(Secundum Atrial Septal Defect)
Interventions: Device: trans catheter device closure
Sponsors: Assiut University
Not yet recruiting

The Effect of Additive On-Demand Sildenafil vs. Dextrose Candy on Maximum Exercise Capacity in Pulmonary Arterial Hypertension

September 17, 2026

Conditions: Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
Interventions: Drug: Dextrose; Drug: Sildenafil 20mg
Sponsors: Silvia Ulrich
Recruiting

Exercise Training Decreases Alcohol Consumption and Tissue Injury by an FGF21-dependent Mechanism

September 17, 2026

Conditions: Alcohol Use Disorder (AUD); Alcohol Related Liver Disease
Interventions: Behavioral: Endurance Exercise
Sponsors: The Cleveland Clinic
Recruiting

Cardiac Arrhythmias in Pediatric Emergency Department

September 17, 2026

Conditions: Arrhythmias, Cardiac; Tachycardia, Supraventricular; Bradycardia
Sponsors: Assiut University
Not yet recruiting

Transcutaneous Regulation for Atrial Prevention in Postoperative Atrial Fibrillation Following OPCAB

September 17, 2026

Conditions: Atrial Fibrillation (AF); OPCABG
Interventions: Device: Transcutaneous Auricular Vagus Nerve Stimulation
Sponsors: Ruijin Hospital
Not yet recruiting

Prevention of Ischemic Stroke Recurrence Using Digital Technology Application

September 17, 2026

Conditions: Ischemic Stroke; Digital Health
Interventions: Device: Digital Prevention Management; Other: Usual Stroke Secondary Prevention Management
Sponsors: Affiliated Hospital of Nantong University
Not yet recruiting

Targeting HealthY Eating to Maintain Energy While Living With Cancer

September 17, 2026

Conditions: Fatigue in Cancer Survivors
Interventions: Behavioral: Nutrition counseling; Behavioral: Time-restricted eating
Sponsors: University of Maryland, Baltimore
Not yet recruiting

Effect of KA-EX Supplementation on Recovery Parameters in High-Level Young Football Players

September 17, 2026

Conditions: Sport; Muscle Fatigue; Recovery of Function (G11.427.698.620); Athletic Performance; Sleep Quality
Interventions: Dietary Supplement: KA-EX; Dietary Supplement: Experimental: KA-EX Supplement
Sponsors: Antonio Molina Lopez; Universidad Europea de Madrid; University of Udine; Universidad Pablo de Olavide
Not yet recruiting

Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.

September 17, 2026

Conditions: ST Elevation (STEMI) Myocardial Infarction; Contrast Induced Nephropathy (CIN); Acute Kidney Injury
Interventions: Diagnostic Test: Total Ischemic Time Evaluation
Sponsors: Assiut University
Not yet recruiting

Long Term Management and Outcomes of Surgical and Non Surgical Infective Endocarditis

September 17, 2026

Conditions: Infective Endocarditis (IE)
Sponsors: Centro Cardiologico Monzino; Istituto Clinico Humanitas; ASST Grande Ospedale Metropolitano Niguarda; Germans Trias i Pujol Hospital; Hospital Universitari Vall d'Hebron Research Institute; UMC Utrecht; Leiden University Medical Center; Helsinki University Central Hospital
Active, not recruiting

Brain Monitors to Reduce Child Confusion After Anesthesia

September 17, 2026

Conditions: Emergence Delirium (Derlenme Deliryumu)
Interventions: Device: BIS-Guided Anesthesia; Drug: Standard Care Anesthesia
Sponsors: Baskent University
Completed

Short-Term Outcomes of HFrEF Patients on Guideline-Directed Medical Therapy

September 17, 2026

Conditions: Heart Failure; Heart Failure, Systolic
Sponsors: Assiut University
Not yet recruiting

Quality of Life Questionnaire in Pulmonary Hypertension EMPHASIS-10: Brazilian Adaptation and Validation

September 16, 2026

Conditions: Pulmonary Hypertension; Quality of Life
Sponsors: Hospital de Clinicas de Porto Alegre
Recruiting

Comparing Pain Science Education to Biomedical Education for People With Knee Osteoarthritis: A Randomized Controlled Trial

September 16, 2026

Conditions: Knee Arthritis Osteoarthritis
Interventions: Behavioral: Pain Science Education; Behavioral: Biomedical Education
Sponsors: McMaster University; The McMaster Institute for Research on Aging (MIRA)
Not yet recruiting

MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG

September 16, 2026

Conditions: Coronary Artery Disease; Systemic Inflammation
Interventions: Procedure: Minimally Invasive Extracorporeal Circulation; Procedure: Conventional Cardiopulmonary Bypass
Sponsors: Bursa Yuksek Ihtisas Training and Research Hospital
Recruiting

Implementing Improved Blood Pressure Measurement in General Practice: A Multisite Implementation Trial Using Automated Office Blood Pressure (AOBP)

September 16, 2026

Conditions: Hypertension; Cardiovascular Diseases (CVD); Vascular Diseases
Interventions: Device: Automated Office Blood Pressure (AOBP) Standardized Measurement Protocol
Sponsors: Menzies Institute for Medical Research; National Health and Medical Research Council, Australia; Hypertension Australia; Australian Cardiovascular Alliance; Pharmaceutical Society of Australia; Ochre Health; Uscom Limited; JA Davey; A&D Australasia; Servier Laboratories (Australia) Pty Ltd; National Heart Foundation, Australia
Not yet recruiting

Vagal Stimulation in Individuals With Stroke

September 16, 2026

Conditions: Stroke; Vagus Nerve Stimulation; Motor Function; Otonomic Function; Cognitive Function
Interventions: Other: vagus nerve stimulation; Other: classic rehabilitation
Sponsors: Nermin KART
Active, not recruiting

ONO-4915 in Patients With Primary Sjogren's Disease

September 16, 2026

Conditions: Sjogren's Disease
Interventions: Drug: ONO-4915; Drug: Placebo
Sponsors: Ono Pharmaceutical Co., Ltd.
Not yet recruiting

Evaluation of the Effectiveness of Lung-Protective Ventilation in Patients Undergoing Laparoscopic Gastrectomy

September 16, 2026

Conditions: Postoperative Pulmonary Complications (PPCs); Atelectasis
Interventions: Procedure: Conventional Ventilation; Procedure: Lung-Protective Ventilation
Sponsors: University Medical Center Ho Chi Minh City (UMC); Hanoi Medical University
Enrolling by invitation

A Prospective Study of Cold Exposure in Patients With MASH

September 16, 2026

Conditions: Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Interventions: Device: Water-Perfused Cooling Suit
Sponsors: Renmin Hospital of Wuhan University
Active, not recruiting

A Study of MGC030 in Participants With Advanced Solid Tumors

September 16, 2026

Conditions: Urothelial Cancer; GastroEsophageal Cancer; Colorectal Cancer; Esophageal Cancer; Gastric Cancer (GC); Pancreatic Cancer
Interventions: Biological: MGC030
Sponsors: MacroGenics
Not yet recruiting

Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities

September 16, 2026

Conditions: Physical Performance Parameters; Exercise Recovery; Cognition; Muscle Damage; Blood Biomarkers; Stress
Interventions: Other: Beef-Based Protein Ready-to-Eat Meals; Other: Plant-Based Protein Ready-to-Eat Meals
Sponsors: Sam Houston State University; National Cattlemen's Beef Association, a contractor to the Beef Checkoff
Recruiting

Renal Doppler Indices for Predicting Acute Kidney Injury After Isolated CABG

September 16, 2026

Conditions: Acute Kidney Injury; Coronary Artery Disease
Interventions: Diagnostic Test: Renal Doppler Ultrasonography
Sponsors: Bursa Yuksek Ihtisas Training and Research Hospital
Not yet recruiting

Cardio-Oncology Rehabilitation in Breast Cancer Patients Undergoing Chemotherapy

September 16, 2026

Conditions: Breast Cancer
Interventions: Behavioral: Cardio-Oncology Exercise Rehabilitation Program
Sponsors: Hospital de Clinicas de Porto Alegre
Recruiting

Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health

September 16, 2026

Conditions: Anxiety; PTSD; ADHD; Depression Disorders; Post-traumatic Stress; Substance Use; Executive Function; Sleep Disturbance
Interventions: Behavioral: AIP-Informed Integrative Psychotherapy; Device: Transcutaneous Auricular Vagus Nerve Stimulation; Behavioral: Regulated Breathing and Autonomic Regulation; Device: Audiovisual Entrainment; Device: Vibroacoustic Stimulation; Behavioral: Breathwork-Based Auditory Driving Entropy Module (BADEM); Device: Transcranial Electrical Stimulation
Sponsors: Tactical Mind Research Coalition, Inc.
Active, not recruiting

"Discovery2" Study of Using MCG at Emergency Departments

September 16, 2026

Conditions: Acute Coronary Syndromes (ACS); Coronary Artery Disease (CAD); Chest Pain; NSTE-ACS (NSTEMI and UA)
Interventions: Device: Magnetocardiography
Sponsors: SB Technology, Inc.
Not yet recruiting

Pembrolizumab and Radiation Therapy With or Without Neoadjuvant Doxorubicin and Ifosfamide for the Treatment of High-Risk Resectable Undifferentiated Pleomorphic Sarcoma or Liposarcoma of the Extremity or Trunk Wall

September 16, 2026

Conditions: Resectable Liposarcoma; Resectable Soft Tissue Sarcoma; Resectable Undifferentiated Pleomorphic Sarcoma
Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Drug: Doxorubicin; Drug: Ifosfamide; Radiation: Intensity-Modulated Radiation Therapy; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Biological: Pembrolizumab; Other: Questionnaire Administration; Procedure: Surgical Procedure; Procedure: Transthoracic Echocardiography Test
Sponsors: Ohio State University Comprehensive Cancer Center; Patient-Centered Outcomes Research Institute
Not yet recruiting

PCCT-Defined High-Risk Plaque and Future Coronary Events: The PREDICT Study

September 16, 2026

Conditions: Coronary Artery Disease; Plaque; Photon-Counting Computed Tomography
Sponsors: Beijing Chao Yang Hospital
Recruiting

Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral Neuropathy

September 16, 2026

Conditions: HIV Associated Polyneuropathy
Interventions: Device: Transcutaneous Auricular Vagus Nerve Stimulation (AVNS)
Sponsors: University of Miami
Not yet recruiting

Non-Invasive Follow-Up of Patients With Coronary Artery Disease Treated With Drug-Coated Balloon PCI Using CT-Derived Fractional Flow Reserve

September 16, 2026

Conditions: Coronary Arterial Disease (CAD); Acute Coronary Syndromes (ACS); Stable Coronary Artery Disease Undergoing PCI
Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Not yet recruiting

Predictive Value of Fetal Modified Myocardial Performance Index for Adverse Perinatal Outcomes in Late Onset Preeclampsia and Diabetes Mellitus

September 16, 2026

Conditions: Pregnancy Diabetic
Sponsors: Assiut University
Not yet recruiting

Molecular Imaging to Identify Predictors of Aortic Valve Disease Activity

September 16, 2026

Conditions: AORTIC VALVE DISEASES; Calcification; Heart
Sponsors: Massachusetts General Hospital
Not yet recruiting

Perinatal Cardiology: Bridging Obstetric and Neonatal Care in CHD

September 16, 2026

Conditions: Congenital Heart Disease; Fetal Heart Disorder; Neonatal Disease; Fetal Disease
Sponsors: Assiut University
Not yet recruiting

Music Therapy During Dental Procedures in Adults With Intellectual and Developmental Disabilities

September 16, 2026

Conditions: Intellectual and Developmental Disabilities; Dental Anxiety
Interventions: Behavioral: Live Music Therapy; Behavioral: Recorded Music
Sponsors: University of Rochester; National Center for Advancing Translational Sciences (NCATS)
Not yet recruiting

A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment

September 16, 2026

Conditions: Overweight/Obesity; Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH); Type 2 Diabetes Mellitus
Interventions: Drug: HRS-4729
Sponsors: Fujian Shengdi Pharmaceutical Co., Ltd.
Recruiting

Assessing Heart and Brain Metabolism in Type II Diabetes Mellitus Patients Using Carbon-13 MRI

September 15, 2026

Conditions: Diabete Type 2
Interventions: Drug: C13 Hyperpolarized pyruvate injection
Sponsors: Sunnybrook Health Sciences Centre
Not yet recruiting

Prehabilitation for Improving Outcomes in Breast Cancer Patients Undergoing Neoadjuvant Systemic Treatment and Surgery

September 15, 2026

Conditions: Breast Carcinoma
Interventions: Other: Aerobic Exercise; Procedure: Bioelectric Impedance Analysis; Other: Consultation; Other: Educational Intervention; Other: Electronic Health Record Review; Other: Nutritional Intervention; Other: Physical Performance Testing; Behavioral: Psychosocial Care; Other: Questionnaire Administration; Other: Referral; Other: Resistance Training; Procedure: Spiritual Therapy; Procedure: Tailored Intervention
Sponsors: City of Hope Medical Center; National Cancer Institute (NCI)
Not yet recruiting

Interprofessional Rehabilitation for Patients With Post-COVID Condition

September 15, 2026

Conditions: PostCovid
Interventions: Other: Interprofessional cognitive group rehabilitation
Sponsors: Danderyd Hospital; Karolinska Institutet
Completed

Effects of Pork Protein on Recovery Following Simulated Fireground Activity

September 15, 2026

Conditions: Exercise Recovery; Physical Performance Parameters; Muscle Damage; Cognition; Blood Biomarkers; Stress
Interventions: Other: Pork-Based Protein Ready-to-Eat Meals; Other: Plant-Based Protein Ready-to-Eat Meals; Other: Carbohydrate-Focused Lower-Protein Ready-to-Eat Meals
Sponsors: Sam Houston State University; National Pork Board
Recruiting

A Plant-Based Diet in the Treatment of Coronary Microvascular Dysfunction

September 15, 2026

Conditions: Coronary Microvascular Dysfunction
Interventions: Other: Polyphenol-Rich Plant-Based Diet
Sponsors: Emory University; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Effects of Virtual Walking on Chronic Pain and Psychological Distress for Individuals With Severe Mobility Impairment

September 15, 2026

Conditions: Severe Mobility Impairment; Spinal Cord Injuries (SCI); Poliomyelitis
Interventions: Behavioral: Virtaul walking; Behavioral: Passive observing video
Sponsors: The Hong Kong Polytechnic University
Active, not recruiting

A Global Randomized Trial Evaluating the FARAFLEX™ Mapping and Pulsed Field Ablation System With Electrographic Flow Mapping in Patients Undergoing Repeat Ablation for Atrial Fibrillation

September 15, 2026

Conditions: Atrial Fibrillation (AF); Persistent Atrial Fibrillation (PersAF); Paroxysmal Atrial Fibrillation (PAF)
Interventions: Device: FARAFLEX Mapping and Pulsed Field Ablation System
Sponsors: Boston Scientific Corporation
Not yet recruiting

Effects of Reiki Therapy in Women With Fibromyalgia: A Randomized Controlled Trial

September 15, 2026

Conditions: Fibromyalgia (FM) OR Fibromyalgia Syndrome
Interventions: Other: Reiki Intervention; Other: Sham Reiki Intervention
Sponsors: Federal University of the Valleys of Jequitinhonha and Mucuri
Recruiting

Atrial Shunt for the Treatment of Heart Failure With Reduced Ejection Fraction

September 15, 2026

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: Device: D-shant Atrial Shunt; Drug: Guideline-Directed Medical Therapy (GDMT) for heart failure with reduced ejection fraction
Sponsors: Beijing Anzhen Hospital; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Recruiting

Physical Exercise in Patients With Chronic Kidney Disease in Hemodialysis (Pehedal-ESKD)

September 15, 2026

Conditions: Chronic Kidney Disease on Hemodialysis; Physical Exercise Behavior (Liking/Aversion)
Interventions: Behavioral: Intradialytic aerobic exercise using a cycle ergometer; Behavioral: Intradialytic elastic-band resistance exercise
Sponsors: Ricerca Nefrocenter; University of Naples; Federico II University
Recruiting

SERENITY Study of Chronic Pain Interference in Adults

September 15, 2026

Conditions: Chronic Low Back Pain; Spinal Cord Injury; Neuropathic Pain; Chronic Pain; Pain Interference
Sponsors: University of Minnesota; National Center for Complementary and Integrative Health (NCCIH)
Not yet recruiting

Safety, Tolerability and PK of ATTO 1091 in Healthy Adult Volunteers and Patients With Ulcerative Colitis

September 15, 2026

Conditions: Ulcerative Colitis (UC)
Interventions: Drug: ATTO-1091; Drug: Placebo
Sponsors: Attovia Therapeutics Inc
Not yet recruiting

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer: A Randomized Controlled Trial

September 15, 2026

Conditions: Advanced Cancer; Stage IV Solid Tumor Cancer; Stage IV Sarcoma of Bone; Stage IV Lymphoma; Stage IV Melanoma; Endocrine Cancer
Interventions: Drug: Psilocybin (25mg); Drug: Psilocybin (1mg); Other: PEARL Therapy
Sponsors: University Health Network, Toronto
Not yet recruiting

The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial

September 15, 2026

Conditions: Critical Illness; Elevated Left Atrial Pressure; Left Ventricular Diastolic Dysfunction; Echocardiography
Interventions: Diagnostic Test: Echocardiography
Sponsors: Queen Mary Hospital, Hong Kong
Recruiting

Lattice vs Pentaspline Comparative Evaluation in Persistent AF

September 15, 2026

Conditions: Persistent Atrial Fibrillation
Interventions: Procedure: Pulmonary vein isolation
Sponsors: Mitera Hospital
Not yet recruiting

First-in-Human Study of the Circle Safe System for Diaphragm Response Monitoring During Pulmonary Vein Ablation

September 15, 2026

Conditions: Atrial Fibrillation
Interventions: Device: Circle Safe System Use During Pulmonary Vein Ablation
Sponsors: Circle Safe, Inc.
Not yet recruiting

Self-training and Resuscitation Techniques: Evaluation of the Performance and Impact on the Quality of Cardiopulmonary Resuscitation (CPR)

September 15, 2026

Conditions: Cardiac Arrest (CA)
Sponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting

NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)

September 15, 2026

Conditions: Type 2 Diabetes; Coronary Heart Disease; Myocardial Infarction; Cerebrovascular Disease; Stroke; Chronic Kidney Disease; Fatty Liver Disease
Interventions: Behavioral: Digital health interventions
Sponsors: University of Eastern Finland; Sitra, the Finnish Innovation Fund; Wellbeing Services County of South Savo (Eloisa); Nightingale Health Plc
Not yet recruiting

Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis

September 15, 2026

Conditions: Interstitial Lung Disease; Pulmonary Hypertension; Systemic Sclerosis
Interventions: Drug: Hyperpolarized 129 Xenon Gas
Sponsors: Bastiaan Driehuys; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

10 Degree C Static Storage in Heart Transplantation

September 14, 2026

Conditions: Transplant, Failure, Heart; Heart Transplant; Heart Failure
Interventions: Device: 10 degree C Static Storage Cooler
Sponsors: John Trahanas
Not yet recruiting

Acute Effect Of Pilates On Blood Pressure In Women

September 14, 2026

Conditions: Elevated Blood Pressure
Interventions: Behavioral: Pilates Exercise; Behavioral: Walking Exercise
Sponsors: Universidade Estadual do Norte do Parana
Completed

Real-World Study of Obstructive Upper Urinary Tract Stones and Acute Pyelonephritis

September 14, 2026

Conditions: Urolithiasis; Strategy Training; Observation; Pyelonephritis Acute
Interventions: Procedure: Ureteral Stent; Procedure: Percutaneous Nephrostomy; Drug: Initial Medical Therapy
Sponsors: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Not yet recruiting

Epicardial Fat Immunity extRa Cellular vesicleS HearT

September 14, 2026

Conditions: Cardiac Surgery
Interventions: Procedure: Epicardial adipose tissue biopsy; Procedure: Thoracic subcutaneous adipose tissue biopsy
Sponsors: Assistance Publique Hopitaux De Marseille
Not yet recruiting

First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

September 14, 2026

Conditions: Obesity
Interventions: Drug: ACCG-2671; Drug: Placebo
Sponsors: Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
Recruiting

Proton Therapy for Mediastinal Lymphoma (PROMLY)

September 14, 2026

Conditions: Mediastinal Lymphoma; Hodgkin Disease Lymphoma; Diffuse Large B Cell Lymphoma (DLBCL)
Interventions: Radiation: Proton therapy
Sponsors: Rigshospitalet, Denmark; Danish Centre for Particle Therapy, Aarhus University Hospital, Denmark; Aalborg University Hospital; Odense University Hospital
Recruiting

Clinical Outcome of Coronary Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention in Patients With Severe Left Ventricular Disfunction (CROWN)

September 14, 2026

Conditions: Coronary Artery Disease; Left Ventricular Cardiac Dysfunction
Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Active, not recruiting

Holistic CRM Care vs Standard of Care in a Primary Care Setting

September 14, 2026

Conditions: Cardio Vascular Disease; Diabetes (DM); Chronic Kidney Disease
Interventions: Other: CRM care
Sponsors: Danderyd Hospital; Boehringer Ingelheim; Karolinska Institutet
Not yet recruiting

Serial Biomarker Testing and Cardiovascular Risk Stratification (ACHILLES)

September 14, 2026

Conditions: Heart Failure; ASCVD; CKD
Sponsors: University Hospital Freiburg
Active, not recruiting

The Variation in Electrode Configuration for Termination of Out-of-Hospital Rhythms That Are Shockable in Cardiac Arrest Trial

September 14, 2026

Conditions: Cardiac Arrest (CA)
Interventions: Device: defibrillator electrode pads
Sponsors: Oregon Health and Science University
Not yet recruiting

Clinical Trial of a MEK Inhibitor for RASopathy-Associated Severe Infantile Hypertrophic Cardiomyopathy: Baby MERIT

September 14, 2026

Conditions: HCM; Noonan Syndrome and Other Rasopathy; Heart Failure (Pediatric)
Interventions: Drug: Trametinib
Sponsors: Carelon Research; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

Renal Oxygenation-Guided AKI Reduction Trial

September 14, 2026

Conditions: Acute Kidney Injury; Hepatectomy
Interventions: Device: INVOS 5100C regional oxygen saturation monitoring system; Other: RrSO2-guided perioperative management; Other: Usual perioperative management
Sponsors: Chinese PLA General Hospital
Not yet recruiting

Yoga Based Cardiac Rehabilitation in Heart Failure Failure

September 14, 2026

Conditions: Heart Failure With Reduced Ejection Fraction; Heart Failure NYHA Class II; Heart Failure NYHA Class III
Interventions: Behavioral: Yoga-CaRe HF; Behavioral: Health Education
Sponsors: Centre for Chronic Disease Control, India; Indian Council of Medical Research; Central Council for Research in Yoga & Naturopathy; All India Institute of Medical Sciences; All India Institute of Medical Sciences, Bathinda; All India Institute of Medical Sciences, Rishikesh; All India Institute of Medical Sciences, Jodhpur; Dayanand Medical College and Hospital; KLES Prabhakar Kore Hospital Belagavi; JSS Medical College Hospital; SDM College of Medical Sciences & Hospital; North Eastern Indira Gandhi Regional Institute of Health ans Medical Sciences; Sri Ramachandra Institute of Higher Education and Research; Madras Medical College; Acharya Vinoba Bhave Rural Hospital; Sri Jayadeva Institute of Cardiovascular Sciences and Research
Recruiting

Drug-Coated Balloon Only Strategy After Recanalization of Chronic Total Coronary Occlusions

September 14, 2026

Conditions: Angina (Stable); Coronary Occlusion; Coronary Artery Disease; Chronic Total Occlusion
Interventions: Device: Paclitaxel-coated balloon (AGENT Paclitaxel-Coated PTCA Balloon Catheter); Procedure: Serial intravascular ultrasound and protocol-mandated nine-month angiographic reassessment
Sponsors: University of Sao Paulo General Hospital; Boston Scientific Corporation
Not yet recruiting

Optimal Timing of Microaxial Flow Pump(Impella CP) in AMI-related Cardiogenic Shock

September 14, 2026

Conditions: Myocardial Infarction (MI); Cardiogenic Shock; ST-Segment Elevation Myocardial Infarction(STEMI); Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
Interventions: Procedure: Routine pre-PCI Impella CP; Procedure: Selective post-PCI Impella CP
Sponsors: Chonnam National University Hospital
Not yet recruiting

A Phase II Study of Irinotecan Liposome Plus Fruquintinib and Sintilimab in Second-Line PD-L1-Positive Advanced Gastric Cancer

September 14, 2026

Conditions: Stomach Neoplasms; Gastric Cancer
Interventions: Drug: Fruquintinib; Biological: Sintilimab; Drug: Irinotecan Hydrochloride Liposome Injection (II)
Sponsors: Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center; Shanghai Hengrui Pharmaceutical Co., Ltd.
Not yet recruiting

Post-Induction Low Cardiac Output Syndrome in Coronary Artery Bypass Graft Surgery

September 14, 2026

Conditions: Cardiac Output, Low; Coronary Arterial Disease; Anesthesia, General
Interventions: Other: routine clinical monitoring, observed only
Sponsors: Ataturk University; Ankara City Hospital Bilkent
Recruiting

Danish Trial of Weight Loss to Reduce Atrial Fibrillation Progression

September 14, 2026

Conditions: Atrial Fibrillation (AF); Obesity & Overweight
Interventions: Other: Structured weight loss program including behavioral support and optional meal re-placement or pharmacotherapy with Glucagon-like peptide-1 receptor agonists (GLP1-RA); Other: Standard Care (in control arm)
Sponsors: Axel Brandes; University Hospital Bispebjerg and Frederiksberg; Rigshospitalet, Denmark; Regionshospital Nordjylland; Viborg Regional Hospital; Holbaek Hospital; Aarhus University Hospital
Not yet recruiting

Pulsed Field Ablation for the Treatment of Persistent Atrial Fibrillation: Pulmonary Vein Plus Superior Vena Cava Isolation Versus Pulmonary Vein Isolation Alone-A Prospective, Multicenter, Randomized Controlled Study

September 14, 2026

Conditions: Persistent Atrial Fibrillation
Interventions: Device: Pulsed Field Ablation - pulmonary vein isolation; Device: Pulsed Field Ablation - Pulmonary Vein Isolation + Superior Vena Cava Isolation
Sponsors: Ruijin Hospital
Not yet recruiting

EFFECTS OF ERAS PROTOCOLS ON PATIENT OUTCOMES IN CARDIOVASCULAR SURGERY

September 14, 2026

Conditions: ERAS Programmes
Interventions: Behavioral: Enhanced Recovery After Surgery (ERAS) Protocol
Sponsors: Karabuk University
Completed

First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).

September 14, 2026

Conditions: Coronary Artery Disease; Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)); In-Stent Restenosis or De Novo Coronary Artery Lesions; In-Stent Stenosis (Restenosis) of Coronary Artery Stent; Small Vessel Disease; CAD - Coronary Artery Disease; CAD; CAD Patients; PTCA; PCI; Stenosis Coronary; Stenosis Artery; Stenotic Coronary Lesion
Interventions: Combination Product: Sirolimus-coated balloon catheter; Combination Product: Sirolimus-coated balloon catheter
Sponsors: Tonic Medical, Inc.; Clinical Accelerator
Recruiting

"Impact of NOciception Level (NOL) Index Intraoperative Guidance of REmifentanil Administration on Opioid Consumption and QoR in Ambulatory Patients Undergoing LAparoscopic Cholecystectomy."

September 14, 2026

Conditions: Elective Laparoscopic Cholecystectomy
Interventions: Device: Remifentanil titration based on Nociception Level Monitor; Other: Remifetanil guided by vital parameters and clinical assessment
Sponsors: Svendborg Hospital; Medtronic
Completed

RSV, Influenza, and SARS-CoV-2 Outcomes in Severely Immunosuppressed Adults

September 11, 2026

Conditions: Respiratory Syncytial Virus Infections; Immunocompromised Host; Influenza; COVID - 19
Sponsors: Hospital Italiano de Buenos Aires; Pfizer
Active, not recruiting

DIY Indoor Air Cleaner Study in Rural and Urban Communities in Colorado

September 11, 2026

Conditions: Indoor Air Quality
Interventions: Behavioral: DIY Air Cleaner and Breathe Clean Video
Sponsors: University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

A Phase 3 Trial of Inhaled Mosliciguat in PH-ILD (PHrontier)

September 11, 2026

Conditions: Pulmonary Hypertension; Interstitial Lung Disease; Vascular Diseases; Cardiovascular Diseases; Fibrosis
Interventions: Drug: Mosliciguat; Drug: Placebo; Device: Dry Powder Inhaler
Sponsors: Pulmovant, Inc.
Recruiting

Clinical Efficacy and Safety of Left Bundle Branch Area Pacing Using Quantitative Guidance of Multimodal Data in the Treatment of Heart Failure

September 11, 2026

Conditions: Heart Failure; Left Bundle Branch Block; Non-ischemic Cardiomyopathy
Interventions: Procedure: Apply multimodal data fusion for quantitative guidance of left bundle branch region pacing; Procedure: Conventional Biventricular Pacing
Sponsors: Second Affiliated Hospital of Nanchang University; The Affiliated Hospital of Inner Mongolia Medical University; Chifeng Municipal Hospital; Hohhot First Hospital, Hohhot, Inner Mongolia, China
Recruiting

Virtual Reality for Pain and Anxiety During HyFoSy

September 11, 2026

Conditions: Infertility
Interventions: Behavioral: virtual reality; Other: rest
Sponsors: HaEmek Medical Center, Israel
Not yet recruiting

Gradual Tapering or Discontinuation of Beta-Blockers After Stabilization With Mavacamten Therapy

September 11, 2026

Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions: Drug: Beta-Blocker Sequential Tapering and Discontinuation; Drug: Beta-Blocker Baseline Stable-Dose Maintenance
Sponsors: First Affiliated Hospital of Wenzhou Medical University
Not yet recruiting

Synthetic Vasomotion for Glymphatic Enhancement

September 11, 2026

Conditions: Parkinson Disease (PD)
Interventions: Device: Active noninvasive vagus nerve stimulation; Device: Sham noninvasive vagus nerve stimulation; Procedure: Active intermittent hypercapnia; Procedure: Sham intermittent hypercapnia; Behavioral: Guided breathing
Sponsors: Florida Institute for Human and Machine Cognition; Applied Cognition
Not yet recruiting

China Elderly Valve Disease Study III (China-DVD3 Study)

September 11, 2026

Conditions: Heart Valve Diseases; Moderate to Severe Valve Disease in the Elderly
Sponsors: Yongjian Wu, MD, PhD
Not yet recruiting

Multimodal Artificial Intelligence for Non-Invasive Colorectal Cancer Screening Based on Holographic Biology

September 11, 2026

Conditions: Colorectal Cancer
Interventions: Other: Multimodal non-invasive detection for colorectal cancer
Sponsors: Xiuli Zuo
Not yet recruiting

Alert-HF: Early Detection and Intervention on Atrial Fibrillation in Heart Failure Patients

September 11, 2026

Conditions: Heart Failure
Interventions: Device: Implantable loop recorder; Device: Patient-driven portable ECG monitoring; Other: Usual Care
Sponsors: Medisch Spectrum Twente
Not yet recruiting

Dancing as an Alternative to the Traditional Exercising in Older Adults With Cardiac Diseases

September 11, 2026

Conditions: Heart Failure and Preserved Ejection Fraction
Interventions: Other: Dancing Intervention; Other: Exercising
Sponsors: University College, London; Azerbaijan state academy of phisycal education and sport
Active, not recruiting

Effect of Pre-operative Program in Open Heart Surgery

September 11, 2026

Conditions: Cardio Vascular Disease; Heart Surgery; Open Heart Surgery; Physical Therapy
Interventions: Other: Multimedia preoperative progarm; Other: Traditional preoperative program
Sponsors: Pajeemas Kittipanya-Ngam
Completed

Finerenone for Premature Ovarian Insufficiency (POI)

September 11, 2026

Conditions: Premature Ovarian Insufficiency
Interventions: Drug: Finerenone; Drug: Placebo
Sponsors: The University of Hong Kong-Shenzhen Hospital
Not yet recruiting

OPtimization of Antiplatelet Therapy After the intervenTION of de Novo Coronary Artery Lesions With Drug-Coated Balloons

September 11, 2026

Conditions: Chronic Coronary Syndrome
Interventions: Drug: 1-month DAPT; Drug: 6-month DAPT
Sponsors: Shanghai Zhongshan Hospital
Not yet recruiting

Effectiveness of Eccentric Cycling Exercise in Ambulatory Rehabilitation for Patients With Cardiopulmonary Diseases: A Pragmatic Randomized Controlled Trial

September 11, 2026

Conditions: Eccentric Cycling Exercise Training
Interventions: Procedure: Eccentric cycling exercise
Sponsors: University of Zurich
Enrolling by invitation

Heart Rate Variability Biofeedback for Anxiety in Autistic Youth

September 11, 2026

Conditions: Autism Spectrum Disorder; Anxiety
Interventions: Device: Lief Smart Patch
Sponsors: Massachusetts General Hospital; Eagles Autism Foundation
Not yet recruiting

Effect of Box Breathing Before Chest Tube Removal After Open-Heart Surgery

September 11, 2026

Conditions: Open-Heart Surgery
Interventions: Behavioral: Box breathing
Sponsors: Mersin University
Not yet recruiting

Three Breathing Techniques for Heart Rate Variability, Attention, Reaction Time, and Anxiety

September 11, 2026

Conditions: Breathing Exercises; Healthy Volunteers
Interventions: Behavioral: Mindfulness Breathing; Behavioral: Box Breathing; Behavioral: Nadi Shodhana Pranayama
Sponsors: Atlas University
Completed

Benefits of Judicial Assistance Dogs for Child Victims in Child Advocacy and Pediatric Assessment Units (UAPEDs)

September 10, 2026

Conditions: Animal-Human Bonding; Animal-assisted Intervention; Behavioural Responses to Contact With Dogs
Interventions: Behavioral: Judicial Assistance Dog
Sponsors: Centre Hospitalier Régional d'Orléans
Not yet recruiting

The DREAM-VR Study: Does a Virtual Reality Tool Help Dental Students Master Acute Medical Emergencies Better?

September 10, 2026

Conditions: Competency; Confidence, Self; Medical Emergency Calls; Dentistry; Virtual Reality
Interventions: Other: DentEmergencyVR tool; Other: Mannikin group
Sponsors: Denise van Diermen
Not yet recruiting

The mHTX APP Program

September 10, 2026

Conditions: Rehabilitation; Follow up
Interventions: Behavioral: Intervention
Sponsors: University of Aarhus; Rigshospitalet, Denmark
Enrolling by invitation

Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia

September 10, 2026

Conditions: Ventricular Tachycardia (VT); Ischemic Cardiomyopathy; Nonischemic Cardiomyopathy
Interventions: Procedure: Selective Substrate Isolation
Sponsors: New York Medical College
Recruiting

Single-Use Spherical Pulsed Ablation Catheter for Paroxysmal Atrial Fibrillation

September 10, 2026

Conditions: Atrial Fibrillation (AF)
Interventions: Device: Investigational Cardiac Pulsed Field Ablation (PFA) System; Device: Conventional Radiofrequency (RF) Catheter Ablation System
Sponsors: Shanghai Shineyo Medical Co., Ltd.
Not yet recruiting

Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension

September 10, 2026

Conditions: Hypertension
Interventions: Device: Digital care pathway for hypertension; Device: Asynchronous communication with nurse
Sponsors: Wellbeing Services County of Pirkanmaa; Tampere University
Not yet recruiting

Establishment of a Perioperative Dynamic Prediction Model for Cardiac Surgery-associated Acute Kidney Injury

September 10, 2026

Conditions: CSA-AKI; Acute Kidney Injury; Cardiovascular Surgery
Sponsors: China National Center for Cardiovascular Diseases
Active, not recruiting

Right Ventricular Afterload Indices in Lung Surgery

September 10, 2026

Conditions: Lung Cancer (Suspected or Confirmed); Thoracoscopic Lobectomy; One Lung Ventillation (OLV)
Interventions: Diagnostic Test: Contrast cardiac magnetic resonance imaging; Diagnostic Test: Right heart catheterisation; Diagnostic Test: Perioperative plasma sampling; Other: Quality of recovery scale
Sponsors: University of Glasgow; Golden Jubilee National Hospital
Not yet recruiting

Clinical Tolerance of an Intraparotid Injection of Bupivacaine, Combined With Dexamethasone, After Parotidectomy for Benign Tumor

September 10, 2026

Conditions: Parotid Neoplasm; Bupivacaine; Dexamethasone
Interventions: Drug: Intraparotid injection of bupivacaine/ dexamethasone
Sponsors: Centre Hospitalier Universitaire de Nīmes
Recruiting

MAGiC - Congenital Heart DIsease

September 10, 2026

Conditions: Supraventricular Tachycardia (SVT); Congenital Heart Disease (CHD)
Interventions: Device: Cardiac ablation using the MAGiC Ablation Catheter
Sponsors: Stereotaxis
Not yet recruiting

Multimodal Physiologic State Intelligence Study

September 10, 2026

Conditions: Heart Failure; Cardiomyopathies; Pulmonary Hypertension; Myocarditis; Acute or Subacute; Myocarditis Due to Drug; Myocarditis Viral; Pericardial Diseases; Valvular Heart Diseases; Hypertension; Sepsis; Acute Kidney Injury; Pulmonary Edema - Acute; Pulmonary Edema With Heart Failure; Pulmonary Edemas; Acute Respiratory Distress Syndrome; Pulmonary Embolism Acute; Pulmonary Embolism (Diagnosis); Pulmonary Embolism Acute Massive; Pulmonary Embolism Subacute Massive; Venous Thrombosis Pulmonary; Venous Thrombosis (Disorder); Venous Thrombosis, Deep; Peripheral Arterial Disease; Peripheral Arterial Disease (PAD); Aortic Diseases; Muskuloskeletal Diseases; Brain Aging; Brain Aneurysm; Brain Aging Related Conditions; Ultrasound; Ultrasound Exams; Ultrasound Guidance
Interventions: Device: OMNIPHYS Multimodal Ultrasound Imaging System
Sponsors: Truway Health, Inc.
Enrolling by invitation

Assessment of Erectile Dysfunction and Coronary Artery Disease Severity

September 10, 2026

Conditions: Erectile Dysfunction and Coronary Artery Disease
Interventions: Other: Selective Coronary Angiography
Sponsors: Assiut University
Not yet recruiting

Heart-Kidney-Diabetes Multidisciplinary Care MOdels for CardiovascuLar Health In Patients With Chronic Kidney DiSease and Diabetes: A PragmaTIC Cluster Randomized Controlled Trial (HOLISTIC)

September 10, 2026

Conditions: Chronic Kidney Disease; Type II Diabetes
Interventions: Other: The intervention with the MCM is Kidney-Heart GDMT initiation and titration for dose optimization (as clinically tolerated), within 4 months of enrollment in the study.
Sponsors: Baim Institute for Clinical Research
Not yet recruiting

PCI Registry Basel

September 10, 2026

Conditions: Coronary Artery Disease; Coronary Stenosis; Coronary Occlusion
Sponsors: University Hospital, Basel, Switzerland
Recruiting

SKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid Tumors

September 10, 2026

Conditions: Selected Advanced Solid Tumors; Colorectal Cancer (CRC); Pancreatic Ductal Adenocarcinoma (PDAC); Biliary Tract Cancer (BTC); Gastric Cancer (GC); Esophageal Cancer (EC); Head and Neck Squamous Cell Cancer (HNSCC)
Interventions: Drug: SKL35501; Diagnostic Test: SKL35502
Sponsors: SK Life Science, Inc.
Recruiting

Venous Closure System After AF Ablation

September 10, 2026

Conditions: Atrial Fibrillation
Interventions: Procedure: Perclose ProGlide™; Procedure: Figure-of-8 suture
Sponsors: Yonsei University
Active, not recruiting

Closed-Loop Stimulation in Left Bundle Branch Area Pacing

September 10, 2026

Conditions: Block Complete Heart; Atrial Fibrillation (AF); Chronotropic Incompetence
Interventions: Device: Closed-Loop Stimulation; Device: Accelerometer-Based VVIR Pacing
Sponsors: Bartlomiej Wrobel
Completed

PRISM Trial: Partial Breast Versus Whole Breast Radiation in Early Breast Cancer

September 10, 2026

Conditions: Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Interventions: Radiation: Ultra-Hypofractionated Partial Breast Irradiation; Radiation: Ultra-Hypofractionated Whole Breast Irradiation
Sponsors: Jinnah Postgraduate Medical Centre
Not yet recruiting

A Trial Assessing the Effectiveness of Evolocumab in Reducing the Plaque Burden in Participants With Subclinical Atheroma

September 10, 2026

Conditions: Coronary Artery Disease; Hypercholesterolemia; Atheroma; Atherosclerotic Plaque
Interventions: Drug: Evolocumab; Drug: Routine Lipid Management; Device: Autoinjector
Sponsors: Amgen
Not yet recruiting

CXCR2 Leucocyte Expression Level as a Predictive Factor of Coronary Artery Calcification Progression in Advanced Chronic Kidney Disease Patients

September 10, 2026

Conditions: Chronic Kidney Disease; Coronary Arteries Calcifications; CXCR2 Expression
Interventions: Other: Thoracic CT; Biological: Blood samples
Sponsors: Centre Hospitalier Universitaire, Amiens
Not yet recruiting

Discovery and Validation of Biomarkers for CSA-AKI Risk Prediction

September 10, 2026

Conditions: CSA-AKI; Acute Kidney Injury; Cardiovascular Surgery; Biomarkers
Sponsors: China National Center for Cardiovascular Diseases
Recruiting

A Prospective Diagnostic Trial of Al[¹⁸F]F-NOTA-folate PET in Patients With Suspected Cardiac Sarcoidosis and Infective Endocarditis

September 10, 2026

Conditions: Cardiac Sarcoidosis; Infective Endocarditis
Interventions: Diagnostic Test: Al[¹⁸F]F-NOTA-folate PET imaging; Diagnostic Test: [15O]water PET imaging; Diagnostic Test: Echocardiography
Sponsors: Turku University Hospital; Helsinki University Central Hospital; Satasairaala
Not yet recruiting

Use of Volta Medical AI-software During Atrial Fibrillation Ablation to Identify Patients Who May Need More Than Pulmonary Vein Isolation.

September 10, 2026

Conditions: Atrial Fibrillation
Interventions: Device: Complete biatrial mapping
Sponsors: Volta Medical
Not yet recruiting

A Study of Darolutamide Plus Androgen Deprivation Therapy in Patients With Metastatic Hormone-sensitive Prostate Cancer in India

September 10, 2026

Conditions: Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Interventions: Drug: Darolutamide plus androgen deprivation therapy
Sponsors: Bayer
Not yet recruiting

ELderly REspiratory VIral Cohort

September 10, 2026

Conditions: Influenza Viruses; Respiratory Syncytial Virus (RSV); Severe Acute Respiratory Syndrome Coronavirus 2; Human Metapneumovirus (hMPV); Parainfluenza Virus (PIV); Adenovirus; Rhinovirus; Coronavirus
Interventions: Other: Respiratory viral infection
Sponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting

Coronary Access After Evolut FX Plus TAVI: Impact of Commissural Alignment and the Large-Cell Frame Design: ACCESS-FX+ Registry

September 10, 2026

Conditions: Severe Aortic Stenosis
Sponsors: Yonsei University
Not yet recruiting

Early Feasibility Study of 3930M Defibrillation Lead Implantation Via the Middle Cardiac Vein in Patients With Tricuspid Valve Regurgitation

September 10, 2026

Conditions: Defibrillator; Tricuspid Valve Regurgitation
Interventions: Device: Defibrillator
Sponsors: Minneapolis Heart Institute Foundation; Cara Medical Ltd
Not yet recruiting

A Method Characterization Study to Evaluate Thermoregulatory Sweat Production in Healthy Volunteers and Patients With ROSAH Syndrome)

September 10, 2026

Conditions: ROSAH Syndrome; Anhidrosis; Hypohidrosis
Interventions: Procedure: Standardized Controlled Heat Exposure With Gravimetric Sweat Collection
Sponsors: The Third Xiangya Hospital of Central South University; Drug Farm Inc
Not yet recruiting

Hematological Profile in Children With Numerical Chromosomal Disorders

September 10, 2026

Conditions: Down Syndrome; Turner Syndrome; Klinefelter Syndrome; Trisomy 18; Chromosome Disorders
Sponsors: Assiut University
Not yet recruiting

Clinical Time and Temporal Dynamics Study (CLIN-TIME)

September 10, 2026

Conditions: Longitudinal Studies; Prospective Studies; Biomarkers; Predictive Value of Tests; Telemedicine; Time of Death; Time Perception; Time Reaction; Time Efficiency; Time Management; Population; Population Groups; Epidemic Disease; Pandemic; Sex Behavior; Sex Characteristics; Sex Hormone; Cardio-pulmonary; Surgical; Drugs of Abuse; Health Risks; Clinical Outcomes
Interventions: Other: No Study-Assigned Intervention
Sponsors: Truway Health, Inc.
Enrolling by invitation

Impact of Asprosin and Neuregulin 4 on Metabolic Parameters, Anthropometric Indices and Body Composition After Laparoscopic Sleeve Gastrectomy

September 10, 2026

Conditions: Bariatric Sleeve Gastrectomy
Interventions: Procedure: sleeve gastrectomy
Sponsors: General Committee of Teaching Hospitals and Institutes, Egypt
Completed

Manual and Self-Lymphatic Drainage Combined With Exercise in Women With Lipedema

September 10, 2026

Conditions: Lipedema
Interventions: Other: Manual Lymphatic Drainage; Other: Aerobic Exercise; Other: Self-Lymphatic Drainage; Other: Physical Activity Guidance
Sponsors: Merve SEVINC GUNDUZ
Recruiting

Radiological Markers for PDA Management in Preterm Infants

September 10, 2026

Conditions: Patent Ductus Arteriosus in Preterm Infants
Interventions: Diagnostic Test: Organ doppler; Diagnostic Test: Echocardiography
Sponsors: Assiut University
Not yet recruiting

Breast Artery Calcification (BAC) and Female Cardiovascular Disease

September 09, 2026

Conditions: Cardiovascular Health Risk Communication; Cardiovascular (CV) Risk; Cardiovascular Disease Prevention
Interventions: Diagnostic Test: Cardiac CT Scan; Diagnostic Test: Bloodwork
Sponsors: Northwell Health
Recruiting

Pedal Pump Clinical Trial on Edema V2

September 09, 2026

Conditions: Lower Extremity Edema; Lower Extremity Edema Chronic; CHF - Congestive Heart Failure; CHF Exacerbation; Chronic Venous Insufficiency, CVI
Interventions: Device: Pedal Pump; Device: Pedal Pump Sham
Sponsors: Hillcrest
Recruiting

Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS

September 09, 2026

Conditions: Polycystic Ovary Syndrome
Interventions: Other: Model-Guided Precision Acupuncture; Behavioral: Personalized Lifestyle Intervention; Other: Conventional Acupuncture; Behavioral: Standard Lifestyle Intervention
Sponsors: Peking University Third Hospital
Recruiting

Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being

September 09, 2026

Conditions: Interoceptive Awareness; Interoception; Alexithymia; Anxiety; Depression Disorders
Interventions: Device: Heart rate feedback from smartwatch
Sponsors: Massachusetts Institute of Technology
Completed

Effect of Stress Ball Use During Femoral Arterial Sheath Removal After Coronary Angiography

September 09, 2026

Conditions: Femoral Arterial Sheath Removal; Stress Ball; Pain; Anxiety; Patient Satisfaction; Hemodynamic Parameters; Nonpharmacological Intervention
Interventions: Behavioral: Stress Ball
Sponsors: Mersin University
Not yet recruiting

Associations Between Physical Activity and Sedentary Behavior Profiles and Carotid Intima-media Thickness in Adolescents With Obesity

September 09, 2026

Conditions: Obese Adolescents
Sponsors: University of Avignon; Institut Saint Pierre
Recruiting

Development and Psychometric Validation of the Medical Dismissal Scale

September 09, 2026

Conditions: Any Condition
Sponsors: King's College London
Active, not recruiting

Wireless Wearable Home Prehabilitation for Older Adults With NSCLC

September 09, 2026

Conditions: Non-Small Cell Lung Cancer (NSCLC); Rehabilitation; Thoracic Surgery; Prehabilitation
Interventions: Behavioral: Digital Home-Based Prehabilitation; Behavioral: Standard Perioperative Care
Sponsors: West China Hospital
Recruiting

Evaluation of the Factors Associated With BRADYcardia Following Pulmonary Vein Isolation Using Pulsed Field Ablation

September 09, 2026

Conditions: Atrial Fibrillation (AF); Pulsed Field Ablation; Bradycardia
Interventions: Procedure: Pulmonary vein isolation
Sponsors: Wroclaw Medical University
Recruiting

Driving Performance in Parkinson's Disease and Multiple Sclerosis Using a Driving Simulator

September 09, 2026

Conditions: Parkinson; Multiple Sclerosis
Interventions: Other: Standardized Driving Simulator Assessment
Sponsors: University Hospital Olomouc; Digiteq Automotive
Not yet recruiting

Artificial Intelligence - Based Opportunistic Coronary Artery Calcium Scoring on Routine Chest-CT Scan

September 09, 2026

Conditions: Coronary Artery Calcification; Cardiovascular Risk; Coronary Artery Disease; End-Stage Renal Disease Requiring Haemodialysis; Emergency Care
Sponsors: University of Cologne; University Hospital of Cologne
Not yet recruiting

Portable Low-Level Laser Therapy for Recovery After a Quadriceps-Dominant Fatiguing Task in Recreational Runners

September 09, 2026

Conditions: Muscle Fatigue Caused by Repetitive Muscle Exercise
Interventions: Device: LLLT; Device: Sham
Sponsors: Chia Nan University of Pharmacy ＆ Science; Lasinmed Medical Electronics Co., Ltd.
Completed

Smartphone AI Assistance for Prehospital ECG Interpretation

September 09, 2026

Conditions: Acute Coronary Syndromes; ST Elevation Myocardial Infarction; Non-ST Elevated Myocardial Infarction; Myocardial Infarction (MI); Diagnostic Errors
Interventions: Diagnostic Test: Smartphone large language model assistance (GPT-4o, version-locked)
Sponsors: École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care; University Hospital, Geneva; Swissrescue.ch, Website for Prehospital Healthcare Providers, Les Pontins, Switzerland
Recruiting

Diagnostic Delay in PHTN

September 09, 2026

Conditions: Delayed Diagnosis Pulmonary Hypertension
Sponsors: Assiut University
Not yet recruiting

A Study of IBI3046 in Participants With Overweight or Obesity

September 09, 2026

Conditions: Obesity and Overweight
Interventions: Drug: IBI3046; Drug: placebo
Sponsors: Innovent Biologics (Suzhou) Co. Ltd.
Not yet recruiting

Hospital-to-Home Transitional Cardiac Rehabilitation After Cardiac Surgery

September 09, 2026

Conditions: Telerehabilitation; Cardiac Rehabilitation; Cardiac Surgical Procedures; Heart Valve Diseases; Coronary Artery Disease
Interventions: Behavioral: Hybrid cardiac rehabilitation; Behavioral: Centre-based cardiac rehabilitation
Sponsors: Cheng-Hsin General Hospital
Completed

Metformin in Parkinson's Disease: Safety and Efficacy

September 09, 2026

Conditions: Parkinsons Disease (PD)
Interventions: Drug: Metformin 500mg
Sponsors: Jinnah Medical & Dental College
Not yet recruiting

HERMES: International Survey and Portable External Power Evaluation During Respiratory Support Transport

September 09, 2026

Conditions: Patient Transport; Respiratory Failure; Noninvasive Ventilation; High-Flow Nasal Oxygen; Mechanical Ventilation; Patient Safety; Transport Safety; Medical Equipment Safety; Electrical Power Continuity
Interventions: Device: Portable External Power Supply
Sponsors: Medipol University
Completed

Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

September 08, 2026

Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)
Interventions: Drug: Mavacamten
Sponsors: Second Affiliated Hospital of Nanchang University
Not yet recruiting

Tele-Rehabilitation After Catheter Ablation in Patients With Atrial Fibrillation

September 08, 2026

Conditions: Atrial Fibrillation (AF)
Interventions: Behavioral: Remotely Supervised Cardiac Telerehabilitation; Other: Usual Care and General Exercise Guidance
Sponsors: Hande Cörüt; The Scientific and Technological Research Council of Turkey
Not yet recruiting

INTUPROS 2-3: Improving First-Pass Intubation Success and Reducing Complications in ICU Patients

September 08, 2026

Conditions: Critical Illness; Airway Management Assessment; Tracheal Intubation; Complications
Sponsors: Spanish Society of Critical Care Medicine and Coronary Units; Hospitales Universitarios Virgen del Rocío; Henares University Hospital; Hospital San Juan de Dios del Aljarafe de Sevilla; Hospital Mutua de Terrassa
Not yet recruiting

Safety and Clinical Performance of the Next-Generation SAFESYNC Transcatheter Heart Valve in Patients With Severe Aortic Stenosis

September 08, 2026

Conditions: Aortic Stenosis Senile; Aortic Stenosis Symptomatic; Aortic Stenosis
Interventions: Device: INOVARE® SAFESYNC Next-Generation Bioprosthetic Heart Valve
Sponsors: Braile Biomedica Ind. Com. e Repr. Ltda.
Not yet recruiting

Evaluation of 4D Intracardiac Echocardiography (ICE) During Structural Heart and Electrophysiology Procedures

September 08, 2026

Conditions: Atrial Fibrillation
Interventions: Device: 4D ICE Adjunct Imaging
Sponsors: The Cleveland Clinic; Siemens Corporation, Corporate Technology
Recruiting

The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue

September 08, 2026

Conditions: Lung Cancer (Diagnosis)
Interventions: Behavioral: Low-Intensity Endurance Continuous Exercise; Behavioral: Low-Intensity Endurance Interval Exercise
Sponsors: Taipei Medical University
Recruiting

Evaluation of the Effectiveness of Music Therapy on Anxiety Levels in Patients With Advanced Cancer Hospitalized in a Palliative Care Unit

September 08, 2026

Conditions: Music Therapy; Palliative Care; Cancer; Anxiety
Interventions: Other: depression management; Other: Kigonki; Other: questionnaire
Sponsors: Centre Hospitalier Universitaire, Amiens; Centre Hospitalier de Bethune; Centre Hospitalier de Douai; Hospital of Lens; GHPSO site de Senlis; CH de Compiegne; Centre Hospitalier de Beauvais
Not yet recruiting

A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus Burden

September 08, 2026

Conditions: ST Elevation Myocardial Infarction (STEMI); Acute Coronary Syndromes (ACS)
Interventions: Device: Drug-Coated Balloon (DCB); Device: Drug-Eluting Stent (DES)
Sponsors: Xijing Hospital
Recruiting

TwichView-guided Atricurium Dose Adjustment Trial

September 08, 2026

Conditions: ARDS; TTM; ECMO; Neuromuscular Blockade Monitoring
Interventions: Device: EMG-based quantitative TOF-guided atracurium titration
Sponsors: Fu Jen Catholic University Hospital
Recruiting

Naloxone for In-Hospital Cardiac Arrest

September 08, 2026

Conditions: Heart Arrest
Interventions: Drug: naloxone; Drug: Placebo
Sponsors: Region Skane; Lund University; Clinical Studies Sweden - Forum South; Copenhagen Trial Unit, Center for Clinical Intervention Research
Not yet recruiting

Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic Risk

September 08, 2026

Conditions: Cardiometabolic Syndrome; Obesity and Cardiovascular Risk; Overweight , Obesity
Interventions: Drug: Bupropion 150 mg; Dietary Supplement: Lyophilized powder from edible mushrooms; Behavioral: Lifestyle Management
Sponsors: Uppsala University
Not yet recruiting

Acute Responses to Walking, Stair Climbing, and Functional Circuit Exercise

September 08, 2026

Conditions: Sedentary Behaviors
Interventions: Behavioral: Walking Protocol; Behavioral: Stair Climbing Protocol; Behavioral: Functional Circuit Protocol
Sponsors: Malatya Turgut Ozal University
Completed

Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain

September 08, 2026

Conditions: Non-specific Chronic Low Back Pain
Interventions: Other: Supervised Progressive Walking Test
Sponsors: University of Rennes 2
Not yet recruiting

Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure

September 04, 2026

Conditions: Heart Failure; Caregiver
Interventions: Behavioral: HEROIC program; Behavioral: Active Comparator Control 1
Sponsors: Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting

HERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport

September 04, 2026

Conditions: Acute Respiratory Failure; Respiratory Insufficiency; Respiratory Distress; Critical Illness; Chronic Respiratory Failure; Cardiorespiratory Failure; Mechanical Ventilation; Noninvasive Ventilation; High-Flow Nasal Oxygen Therapy; Advanced Respiratory Support; Patient Transport; Transport of Critically Ill Patients; Patient Safety During Transport; Patient Safety
Interventions: Other: Advanced Respiratory Support During Patient Transport
Sponsors: Medipol University; International Association of Non Invasive Ventilation; International Academy of Non Invasive Ventilation; International College of Non Invasive Ventilation
Not yet recruiting

KV-PREDICT Diagnostic Device in Patients With Heart Failure

September 04, 2026

Conditions: Heart Failure
Interventions: Device: KV-PREDICT
Sponsors: KardioVis S.r.l.
Not yet recruiting

Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients.

September 04, 2026

Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Other: Resistance Exercise without tourniquet; Other: Blood flow restriction resistance exercise
Sponsors: Rashid Latif Medical College
Recruiting

Short Sprint Interval Training in People With Multiple Sclerosis

September 04, 2026

Conditions: Multiple Sclerosis
Interventions: Other: Short sprint interval training
Sponsors: Universidad de León; Hasselt University; University of Leon; El Bierzo Hospital; Sil Multiple Sclerosis Association
Recruiting

Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH

September 04, 2026

Conditions: Pulmonary Arterial Hypertension (PAH); Pulmonary Vascular Disease; High Altitude; Echocardiography; Pulmonary Resistance; Hemodynamic Changes
Interventions: Behavioral: Descent from 2850m to sea level
Sponsors: Silvia Ulrich Somaini
Not yet recruiting

Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department

September 04, 2026

Conditions: Pulmonary Embolism; Venous Thromboembolism; Acute Pulmonary Embolism
Interventions: Other: 2026 AHA/ACC Clinical Risk Categorization
Sponsors: Marmara University Pendik Training and Research Hospital
Recruiting

Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)

September 04, 2026

Conditions: PHYSIOLOGICAL PHENOMENA; Homeostasis; Physical Functional Performance; Cardiorespiratory Fitness; Cardiometabolic Risk Factors; Mobility Limitation
Interventions: Procedure: Standardized Physiologic Resilience Challenge; Other: Multimodal Whole-Body Physiologic Monitoring; Other: Research-Only Whole-Body Digital Twin Analysis
Sponsors: Truway Health, Inc.
Enrolling by invitation

Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes

September 04, 2026

Conditions: Type 1 Diabetes Mellitus
Interventions: Drug: Verapamil oral; Drug: Placebo
Sponsors: Ain Shams University
Recruiting

Neurovascular Unit for Aged Patients With Geriatric Care and Evaluation of Factors Associated With Autonomy Loss

September 04, 2026

Conditions: Stroke
Interventions: Other: Not applicable- observational study
Sponsors: Hospices Civils de Lyon
Not yet recruiting

Rotational Atherectomy and Drug-Coated Balloon Angioplasty With Embolic Protection for Superficial Femoral Artery Occlusions

September 04, 2026

Conditions: Peripheral Artery Disease; Atherectomy in Diseased Lower Extremity Arteries
Interventions: Device: Rotational Atherectomy With Distal Embolic Protection and Drug-Coated Balloon Angioplasty
Sponsors: Sakarya University
Not yet recruiting

This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder

September 04, 2026

Conditions: Autism Spectrum Disorder (ASD); Cardiometabolic Health Indicators; Cardiometabolic Risk Factors; Metabolic Syndrome; Prediabetes
Sponsors: University of Virginia
Recruiting

Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals

September 04, 2026

Conditions: High Altitude; Healthy; Healthy Adult; High Altitude Effects; Pulmonary Resistance; Hemodynamic Changes; Echocardiography
Interventions: Behavioral: Re-Ascent from sea level to 2850m
Sponsors: Silvia Ulrich Somaini
Not yet recruiting

High-Intensity Interval Exercise in Bronchiectasis Patients

September 04, 2026

Conditions: Bronchiectasis, Non-Cystic Fibrosis; High Intensity Interval Exercise
Interventions: Other: high-intensity interval exercise; Other: Airway clearance tecniques
Sponsors: Saglik Bilimleri Universitesi
Recruiting

SST in Emergency Education

September 04, 2026

Conditions: Cardiac and Respiratory Arrest
Interventions: Other: case-based scenario simulation teaching
Sponsors: Second Affiliated Hospital, Zhejiang University, School of Medicine
Completed

Non-Invasive Coronary Functional Evaluation of Patients With Single-vessel Coronary Artery Disease

September 04, 2026

Conditions: PCI Patients; Single Coronary Vessel Disease
Interventions: Diagnostic Test: Coronary flow reserve assessed by Echocardiography
Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not yet recruiting

Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH

September 04, 2026

Conditions: Pulmonary Arterial Hypertension (PAH); Pulmonary Vascular Disease; High Altitude; Echocardiography; Pulmonary Resistance
Interventions: Behavioral: Re-Ascent from sea level to 2850m
Sponsors: Silvia Ulrich Somaini
Not yet recruiting

IL-18 Armored STEAP1 CAR T Cells for the Treatment of Metastatic Castration Resistant Prostate Cancer

September 04, 2026

Conditions: Metastatic Castration-Resistant Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8
Interventions: Biological: FH-STEAP1 IL-18 CAR T cells; Drug: Antiandrogen Therapy; Procedure: Biospecimen Collection; Procedure: Bone Scan; Procedure: Computed Tomography; Drug: Cyclophosphamide; Procedure: Echocardiography Test; Drug: Fludarabine; Procedure: Leukapheresis; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography; Procedure: Biopsy Procedure
Sponsors: Fred Hutchinson Cancer Center; PromiCell Therapeutics, Inc.
Not yet recruiting

AI-Supported Care Engagement for Next-step Delivery - Medicare Advantage

September 04, 2026

Conditions: Population Health Management; Patient Navigation
Interventions: Other: AI-Supported Rising-Risk Care Navigation
Sponsors: Intermountain Health Care, Inc.
Enrolling by invitation

Time Restricted Eating and Meal Frequency for Appetite Control

September 04, 2026

Conditions: Obesity; Meal Frequency; Appetite; Body Composition; Glycaemic Response; Time-restricted Eating
Interventions: Other: MT1; Other: MT2
Sponsors: University of Aberdeen
Completed

Assessment of Total Pulmonary Resistance sPAP/CO Between High Altitude HA vs. Sea Level LA in Healthy Individuals H

September 04, 2026

Conditions: High Altitude; Healthy Adult; Echocardiography; Pulmonary Resistance; Hemodynamic Changes; Healthy
Interventions: Behavioral: Descent from 2850m to sea level
Sponsors: Silvia Ulrich Somaini
Not yet recruiting

Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal Capture

September 04, 2026

Conditions: Bradycardia; Atrioventricular Block; Sick Sinus Syndrome; Cardiac Pacing; Artificial; Heart Conduction System; Bundle-Branch Block; Ventricular Dysfunction; Left; Cardiomyopathies
Interventions: Procedure: LBBAP with mandatory left ventricular conduction system capture (LBBP or LFP); Procedure: LBBAP with left ventricular septal capture as the accepted procedural endpoint (LVSP)
Sponsors: Yonsei University
Not yet recruiting

Evaluation of the Association Between the VEXUS Score and Hemodynamic Status and the Occurrence of Acute Kidney Injury After Open-Heart Surgery

September 04, 2026

Conditions: Acute Kidney Injury After Open Heart Surgery; Venous Congestion After Open Heart Surgery
Sponsors: Hanoi Medical University
Recruiting

Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH

September 04, 2026

Conditions: Pulmonary Arterial Hypertension (PAH); Pulmonary Vascular Disease; Six-minute Walk Test; High Altitude Effects; High Altitude
Interventions: Behavioral: Descent from 2850m to sea level
Sponsors: Silvia Ulrich Somaini
Not yet recruiting

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

September 04, 2026

Conditions: Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions: Device: Pacemaker
Sponsors: Minneapolis Heart Institute Foundation; Cara Medical Ltd
Not yet recruiting