ClinicalTrials.gov: Other terms: heart disease | First posted in the last 14 days
Studies found on ClinicalTrials.gov by a search of: Other terms: heart disease | First posted in the last 14 days
Comparison of Live and Virtual Music-based Interventions in Mitigating Stress: A Pilot Study
May 12, 2026
Conditions: Stress; Dementia; Cognitive ImpairmentInterventions: Behavioral: Live music therapy; Behavioral: Virtual music therapy
Sponsors: University of Pennsylvania; Conestoga High School
Completed
Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)
May 12, 2026
Conditions: Acute Kidney Failure; Renal Replacement Therapy for Acute Kidney Injury in ICU; Sedation in Intensive Care Unit Patients; Sedation in the ICU; Sedation in Intensive Care; Blood Pressure; Mean Arterial Pressure Targets; Temperature; Fever; Resuscitated Sudden Cardiac Death; Out of Hospital Cardiac Arrest; Cardiac Arrest (CA)Interventions: Device: Feedback-controlled temperature device; Other: High MAP; Other: Deep sedation; Other: Fever control without a device; Other: Low MAP; Other: Minimal sedation
Sponsors: Helsinki University Central Hospital
Recruiting
Study Evaluating ISM8969 in Healthy Adult and Elderly Participants and Obese Adult Participants at Risk of Cardiovascular Disease
May 12, 2026
Conditions: Healthy Subjects (HS); Elderly Participants; Obese Adult Participants at Risk of Cardiovascular DiseaseInterventions: Drug: ISM8969 tablets or placebo; Drug: ISM8969 tablets or placebo; Drug: ISM8969 tablets or placebo
Sponsors: InSilico Medicine Hong Kong Limited
Not yet recruiting
Early Screening for Cardiac Amyloid Using a History of Bilateral Carpal Tunnel Syndrome
May 12, 2026
Conditions: Bilateral Carpal Tunnel Syndrome (Diagnosis); Cardiac AmyloidosisInterventions: Diagnostic Test: Technetium-99m Pyrophosphate (Tc-99m PYP) Scan
Sponsors: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Not yet recruiting
VirtualPark_Pediatric
May 12, 2026
Conditions: Dystrophinopathy; Muscular Dystrophies; Congenital MyopathiesInterventions: Device: Dual-task cycling; Other: Standard therapy
Sponsors: Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato; IRCCS National Neurological Institute "C. Mondino" Foundation; IRCCS Eugenio Medea; Fondazione Don Carlo Gnocchi Onlus; IRCCS Fondazione Stella Maris
Not yet recruiting
Exercise-induced Epigenetic Adaptations
May 12, 2026
Conditions: Heart FailureInterventions: Behavioral: high-intensity interval training
Sponsors: Chang Gung Memorial Hospital
Completed
Mind Your Heart Intervention for American Indian Women
May 12, 2026
Conditions: Cardiovascular HealthInterventions: Behavioral: Culturally-adapted intervention to improve cardiovascular health in American Indian women
Sponsors: University of North Carolina, Chapel Hill; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting
AI-Enhanced Single-Lead ECG Screening for Coronary Stenosis
May 12, 2026
Conditions: Ischemic Heart Disease; Coronary Artery Stenosis; Stable Angina Pectoris; Acute Coronary SyndromesInterventions: Diagnostic Test: single-channel electrocardiogram
Sponsors: I.M. Sechenov First Moscow State Medical University
Not yet recruiting
A Study to Evaluate JL18008 in Subject With HIV Immunological Non-Responders
May 12, 2026
Conditions: HIV InfectionsInterventions: Drug: JL18008 20 μg/kg; Drug: Placebo (for 20 μg/kg Group); Drug: JL18008 40 μg/kg; Drug: Placebo (for 40 μg/kg Group); Drug: JL18008 70 μg/kg; Drug: Placebo (for 70 μg/kg Group)
Sponsors: Jecho Biopharmaceuticals Co., Ltd.
Not yet recruiting
Effectiveness of an AI-Enabled Mobile Intervention on Lifestyle Behaviors and Maternal-Infant Health
May 12, 2026
Conditions: Mobile Health Apps; Lifestyle Intervention; Prevention; Multi-component Based Behavioral InterventionInterventions: Behavioral: Multi-component lifestyle intervention
Sponsors: Fangbiao Tao
Not yet recruiting
Long-Term Follow-up Study of FURESTEM-AD in Patients With Atopic Dermatitis(K0106)
May 12, 2026
Conditions: Dermatitis, AtopicSponsors: Kang Stem Biotech Co., Ltd.
Active, not recruiting
Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS) Abnormal Uterine Bleeding Safety Study
May 12, 2026
Conditions: Uterine HemorrhageInterventions: Device: Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS)
Sponsors: Aqua Therapeutics, Inc.
Completed
Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
May 12, 2026
Conditions: Acute Myeloid Leukemia With Complex Karyotype; Myelodysplastic Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Recurrent Secondary Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome; Refractory Secondary Acute Myeloid LeukemiaInterventions: Procedure: Biospecimen Collection; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Procedure: Echocardiography Test; Drug: Fludarabine Phosphate; Drug: Melphalan; Procedure: Multigated Acquisition Scan; Biological: Palifermin; Procedure: Peripheral Blood Stem Cell Transplantation; Other: Questionnaire Administration; Drug: Sirolimus; Drug: Tacrolimus; Radiation: Total Marrow and Lymphoid Irradiation
Sponsors: City of Hope Medical Center; National Cancer Institute (NCI)
Not yet recruiting
Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention
May 12, 2026
Conditions: Hypercholesterolemia; Atherosclerotic Cardiovascular Disease (ASCVD)Interventions: Drug: Inclisiran; Drug: Alirocumab
Sponsors: University Medical Centre Ljubljana
Not yet recruiting
A Phase I Study of [18F]Flortaucipir PET Imaging in Chinese Subjects: Safety, Pharmacokinetics, Biodistribution, Radiation Dosimetry, and Preliminary Diagnostic Efficacy
May 12, 2026
Conditions: AD - Alzheimer's Disease; MCIInterventions: Drug: [18F]Flortaucipir Injection
Sponsors: Eli Radiopharma
Recruiting
Investigation of the Effect of Structured Energy Conservation Techniques Training on COPD Patients
May 12, 2026
Conditions: Pulmonary Disease, Chronic Obstructive (COPD)Interventions: Other: Structured Energy Conservation Techniques Training
Sponsors: Akdeniz University
Not yet recruiting
Feasibility of Protocolised Analgosedation in ECMO
May 12, 2026
Conditions: Intensive Care (ICU); Respiratory Distress Syndrome (RDS); Sedation and Analgesia; Extracorporeal Membrane Oxygenation; Sedation for Mechanical Ventilation; Cardiogenic Shock; Opioid Analgesia; AnalgesiaInterventions: Other: Sedation protocol
Sponsors: Guy's and St Thomas' NHS Foundation Trust; King's College London
Not yet recruiting
Studying Heart Ablation After Left Atrial Closure in High-Bleeding-Risk Atrial Fibrillation Patients
May 12, 2026
Conditions: Atrial Fibrillation; Atrial ArrhythmiaInterventions: Other: Data collection
Sponsors: University of Chicago; Rush University
Completed
Cost-effectiveness of a RE-AIM-Informed Autonomy-Competence Intervention to Improve Medication Adherence and Quality of Life Among Patients With Heart Failure
May 12, 2026
Conditions: Heart Failure; Chronic Heart Failure (CHF)Interventions: Behavioral: RE-AIM-informed autonomy-competence intervention
Sponsors: Universiti Putra Malaysia
Not yet recruiting
A Prospective Registry Study of Patients With Hypertension
May 12, 2026
Conditions: Hypertension (HTN); Hypertension; Blood Pressure, HighSponsors: Vivek Bhalla; Idorsia Pharmaceuticals Ltd.; Duke University Medical Center, Durham, NC
Not yet recruiting
Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing
May 12, 2026
Conditions: Early Risk Screening for Sleep Disordered Breathing in a Dental Setting; Sleep Disordered Breathing (SDB); Obstructive Sleep Apnea (OSA)Interventions: Device: SleepImage Ring
Sponsors: University of North Carolina, Chapel Hill
Not yet recruiting
Platelets and Extracorporeal Membrane Oxygenation Veno-venous
May 12, 2026
Conditions: Extracorporeal Membrane Oxygenation Complication; Hemorrhage; Blood Platelet Disorder; ThrombosisInterventions: Other: blood draws
Sponsors: University Hospital, Toulouse
Not yet recruiting
Sex-Based Disparities in the Electrophysiological Substrate for Atrial Fibrillation and Its Impact on Clinical Outcomes
May 12, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Device: Identifying extra-PV SRG sites
Sponsors: Anat Milman
Not yet recruiting
Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery
May 12, 2026
Conditions: Pediatric Anesthesia; Preoperative Anxiety; Emergence AgitationInterventions: Drug: Dexmedetomidine; Drug: Midazolam
Sponsors: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Recruiting
Treatment of Low-flow Vascular Malformations With Bleomycin Electrosclerotherapy (BEST)
May 12, 2026
Conditions: Vascular MalformationsInterventions: Drug: Bleomycin Sulfate
Sponsors: Institute of Oncology Ljubljana; University Medical Centre Ljubljana
Not yet recruiting
Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)
May 12, 2026
Conditions: B-All; Acute Lymphoblastic LeukemiaInterventions: Biological: TSLPR-CART; Drug: Cyclophosphamide; Drug: Fludarabine
Sponsors: National Cancer Institute (NCI)
Not yet recruiting
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
May 12, 2026
Conditions: Psoriatic Arthritis; Osteoarthitis; Knee; Diabetes (DM); Type 2 Diabetes Mellitus (T2DM); Obesity (Disorder); Insulin Resistance Syndrome; Metabolic Syndrome; Heart Failure; Preserved Ejection Fraction; Coronary Artery Disease; Atrial Fibrillation (AF); Non Alcholic Fatty Liver Disease; Sarcopenia; PericardiumInterventions: Drug: Tirzepatide
Sponsors: JULIO GRANADOS MONTIEL; Instituto Nacional de Cardiologia Ignacio Chavez; Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran; Metropolitan Autonomous University; Universidad Nacional Autonoma de Mexico
Not yet recruiting
Ultrasound-Guided Pudendal vs Dorsal Penile Nerve Block for Pediatric Hypospadias Surgery
May 12, 2026
Conditions: Hypospadias; Pudendal Nerve Block; Penile Nerve Block; Postoperative PainInterventions: Procedure: Ultrasound-Guided Pudendal Nerve Block; Procedure: Ultrasound-Guided Dorsal Penile Nerve Block
Sponsors: Bangladesh Medical University
Completed
The SCAPIS-Snus Study
May 12, 2026
Conditions: Nicotine; Mental Health; Cardiovascular (CV) Risk; Metabolic AbnormalitiesSponsors: Karolinska Institutet; Medical University of Vienna; Uppsala University Hospital; University Hospital, Umeå; Lund University Hospital; Department of clinical sciences at Danderyd hospital
Active, not recruiting
Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery
May 12, 2026
Conditions: Older Patients; Surgery; Dexmedetomidine; Esketamine; Transcranial Direct Current Stimulation; Cognitive Function; SurvivalInterventions: Drug: Dex-Esk; Drug: Placebo; Device: Active tDCS; Device: Sham tDCS
Sponsors: Peking University First Hospital; Peking University Shenzhen Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang University; Fujian Medical University Union Hospital; The First Affiliated Hospital of Air Force Medicial University; Zhejiang University
Not yet recruiting
Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance
May 12, 2026
Conditions: Adenocarcinoma; Prostate Cancer; Neoplasms; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic TypeInterventions: Biological: TriAdeno vaccine; Drug: N-803
Sponsors: National Cancer Institute (NCI)
Not yet recruiting
Effects of Timed Restricted Eating on Body Composition, Metabolism, and Cardiovascular Health
May 12, 2026
Conditions: Intermittent FastingInterventions: Behavioral: Time-Restricted Eating (TRE); Behavioral: Time-Restricted Eating with Intermittent Energy Restriction (TRE+IER)
Sponsors: University of South Alabama
Not yet recruiting
Bern Intracoronary Optical Coherence Tomography and Coronary Computed Tomography Angiography Registry
May 12, 2026
Conditions: Coronary Artery Disease (CAD)Sponsors: Insel Gruppe AG, University Hospital Bern
Recruiting
Study on the Incidence and Risk Factors of Systemic Arterial Gas Embolism in Bronchoscopy Procedures
May 12, 2026
Conditions: Embolism Vein; Air EmbolismSponsors: The Affiliated Hospital of Qingdao University
Completed
CHIP-CC Registry: A Prospective Multicenter Registry of Complex High-Risk PCI in China
May 12, 2026
Conditions: Coronary Artery Disease; High Risk PCI; Percutaneous Coronary Intervention (PCI)Interventions: Procedure: Percutaneous Coronary Intervention; Device: Mechanical Circulatory Support
Sponsors: Guofeng Gao; Shenzhen Core Medical Technology CO.,LTD.
Not yet recruiting
Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure
May 12, 2026
Conditions: Heart FailureInterventions: Behavioral: Dual-Task IMT; Behavioral: IMT
Sponsors: Istanbul University - Cerrahpasa
Not yet recruiting
Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery
May 12, 2026
Conditions: Older Patients; Surgery; Dexmedetomidine; Esketamine; Transcranial Direct Current Stimulation; Perioperative Neurocognitive DisordersInterventions: Drug: Dex-Esk; Drug: Placebo; Device: Active tDCS; Device: Sham tDCS
Sponsors: Peking University First Hospital; Peking University Shenzhen Hospital; The First Affiliated Hospital of Air Force Medicial University; Zhejiang University; Second Affiliated Hospital, School of Medicine, Zhejiang University; Fujian Medical University Union Hospital
Not yet recruiting
Social Determinants of Sleep Health Among Bhutanese Refugees Living in Central Ohio
May 12, 2026
Conditions: SleepSponsors: National Institute of Environmental Health Sciences (NIEHS)
Not yet recruiting
Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease
May 12, 2026
Conditions: Sickle Cell Disease, Hemolytic AnemiaInterventions: Drug: VAS-101
Sponsors: National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach
May 12, 2026
Conditions: Congenital Heart Disease; Postoperative Care; Child Development; Roy Adaptation Model-based Nursing Empowerment ProgramInterventions: Behavioral: RAM-based Nursing Empowerment Program; Other: Routine Care and Educational Booklet
Sponsors: Cukurova University
Not yet recruiting
Screening, Characterization, and Longitudinal Follow-up of Patients With Cardiac Amyloidosis
May 11, 2026
Conditions: Amyloidosis Cardiac; Heart Failure; Cardiac MRI; Spectroscopic Analysis; Diagnosis; PhenotypingSponsors: Heinrich-Heine University, Duesseldorf
Not yet recruiting
PASCAL Precision-GDMT Registry
May 11, 2026
Conditions: Tricuspid Insufficiency; Tricuspid Regurgitation (TR); Left Ventricular Cardiac Dysfunction; Left Ventricular (LV) Systolic Dysfunction; Left Ventricular Dysfunction; Left Ventricular Ejection FractionSponsors: Ceric Sàrl
Not yet recruiting
Pulsed Field Ablation in the Coronary Sinus: Feasibility and Safety of a Novel Approach for Mitral Isthmus Block
May 11, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Procedure: Focal Pulsed Field Ablation of the Coronary Sinus
Sponsors: Shanghai Zhongshan Hospital
Not yet recruiting
Comparative Effects of Elliptical Exercises and Swiss Ball Aerobics Exercises in Post CABG Patients
May 11, 2026
Conditions: CABGInterventions: Other: elliptical exercises; Other: swiss ball exercises
Sponsors: Riphah International University
Not yet recruiting
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CTX001 in Healthy Adults.
May 11, 2026
Conditions: Anemia; Iron Deficiencies; Chronic Kidney DiseaseInterventions: Drug: CTX001 With and Without Iron; Drug: CTX001 With Iron; Drug: CTX001 Multiple Dose; Drug: Placebo With and Without Iron; Drug: Placebo With Iron; Drug: Placebo Multiple Dose
Sponsors: Cajal Therapeutics Inc.
Not yet recruiting
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
May 11, 2026
Conditions: Postoperative Cognitive Complications; Delirium; Perioperative/Postoperative Complications; Brain Injuries; AnesthesiaSponsors: University of Texas Southwestern Medical Center
Not yet recruiting
Unilateral and Bilateral taVNS in Fibromyalgia
May 11, 2026
Conditions: Fibromyalgia SyndromeInterventions: Device: taVNS; Behavioral: Home Exercise Program
Sponsors: Istanbul Gelisim University; Bahçeşehir University
Completed
A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis
May 11, 2026
Conditions: BronchiectasisInterventions: Drug: CHF10196 tablets (florensocatib); Drug: Placebo
Sponsors: Chiesi Farmaceutici S.p.A.
Not yet recruiting
Effects of Breathing Retraining Exercises in Pregnant Females With Postural Orthostatic Tachycardia Syndrome.
May 11, 2026
Conditions: Orthostatic Hypotension; Heart Rate; Blood PressureInterventions: Other: diaphragmatic breathing exercise; Other: educational retraining
Sponsors: Riphah International University
Recruiting
AI-assisted CT for Risk Stratification in Coronary Artery Disease (ACTION)
May 11, 2026
Conditions: Coronary Artery Disease (CAD); Computed Tomography Angiography; Biomarkers; AI (Artificial Intelligence); Lipoprotein(a); Atheroscleroses, Coronary; Myocardial IschemiaSponsors: University of Galway; Science Foundation Ireland
Recruiting
Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage
May 11, 2026
Conditions: Subarachnoid Hemorrhage, Aneurysmal; Delayed Cerebral Ischemia; Cerebral Vasospasm; Autonomic Nervous System DiseasesInterventions: Procedure: Right-Sided Cervical Sympathetic Block at C6; Device: Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
Sponsors: University of Texas Southwestern Medical Center
Not yet recruiting
Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Congenital Diaphragmatic Hernia (CDH)
May 11, 2026
Conditions: Congenital Diaphragmatic HerniaInterventions: Device: FETO with Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100)
Sponsors: Dr Erin Perrone
Not yet recruiting
Infusion of Furosemide to Improve Diuretic Efficiency in Acute Heart Failure
May 11, 2026
Conditions: Acute Heart Failure; Volume OverloadInterventions: Drug: Intravenous furosemide continuous infusion; Drug: Intravenous furosemide bolus injections
Sponsors: University of Aarhus; Central Denmark Region
Not yet recruiting
Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.
May 11, 2026
Conditions: Pulmonary Thromboendarterectomy; Pulmonary Embolism and ThrombosisInterventions: Diagnostic Test: Electrical Impedance Tomography (EIT).; Diagnostic Test: Pulmonary Perfusion SPECT-CT.; Procedure: Pulmonary Thromboendarterectomy.
Sponsors: University of Sao Paulo General Hospital
Recruiting
CLEAR Model for Predicting Ventilatory Liberation in Severe COPD
May 11, 2026
Conditions: Chronic Obstructive Pulmonary DiseaseSponsors: Assiut University
Recruiting
EWSs and 28-Day Mortality in Geriatric ED Patients
May 11, 2026
Conditions: Mortality; Clinical Deterioration; Geriatric Patients; Frailty; Emergency Department VisitsInterventions: Other: Demographic Characteristics; Other: Comorbidities; Other: Vital Signs; Other: Laboratory Parameters; Other: Severity Scores; Other: Clinical Frailty Scale; Other: Early Warning Scores
Sponsors: Haseki Training and Research Hospital
Completed
Safety and Tolerance of a Novel Three-Strain Probiotic in Healthy Adults
May 11, 2026
Conditions: Healthy AdultsInterventions: Dietary Supplement: Three-Strain Probiotic; Dietary Supplement: Phase 2 - Placebo
Sponsors: Pendulum Therapeutics; Atlantia Food Clinical Trials; APC Microbiome Ireland
Active, not recruiting
Familial Risk of AAA in Sweden
May 11, 2026
Conditions: Abdominal Aneurysm; Aortic Aneurysm; Aortic Aneurysm AbdominalSponsors: Karolinska University Hospital; Karolinska Institutet; Swedish Heart Lung Foundation
Active, not recruiting
Catheter-Oriented Unloading and Recovery With a Left Ventricular Assist Gear: Efficacy in Post Cardiotomy Cardiogenic Shock
May 11, 2026
Conditions: Cardiogenic ShockInterventions: Device: SynFlow Duro
Sponsors: ForQaly Medical (Shanghai) Co., Ltd
Not yet recruiting
PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2
May 11, 2026
Conditions: Coronary Artery DiseaseInterventions: Procedure: Initial Invasive Strategy; Drug: Initial Conservative Strategy
Sponsors: Seung-Jung Park; CardioVascular Research Foundation, Korea
Not yet recruiting
Suzetrigine vs Norco-postoperative Mohs Pain
May 11, 2026
Conditions: Cutaneous Tumors; Mohs Micrographic SurgeryInterventions: Drug: Norco 5Mg-325Mg Tablet; Drug: Suzetrigine
Sponsors: Baylor Research Institute
Enrolling by invitation
Empowering Faith-based Communities to Provide Personalized Diabetes Self-management Education and Support (DSMES) in the Magic City
May 11, 2026
Conditions: Blood Cholesterol; Blood Pressure Monitoring; Weight Change; BMI; Diabetes Education; Diabetes (DM)Interventions: Behavioral: Remote Patient Monitoring in a Faith-Based Program; Behavioral: Traditional Cohort Faith-based DSMES program
Sponsors: University of Alabama at Birmingham; National Institute on Minority Health and Health Disparities (NIMHD)
Not yet recruiting
Aspirin Versus Clopidogrel in Chronic Coronary Syndrome in Arabian Gulf Countries
May 11, 2026
Conditions: Chronic Coronary SyndromeInterventions: Drug: Aspirin; Drug: Clopidgrel 75 mg daily
Sponsors: Khalid F Alhabib
Not yet recruiting
OKT With Gaze and Postural Stabilization on Vertigo, MS and QOL in VBH
May 08, 2026
Conditions: Vestibular DisorderInterventions: Other: Group A Habituation exercises; Other: Group B Optokinetic training protocol
Sponsors: Riphah International University
Not yet recruiting
AIC Genotyping Study
May 08, 2026
Conditions: Cardiomyopathy; Atrial Fibrillation (AF); GeneticSponsors: Barts & The London NHS Trust
Recruiting
NORM-HF Pivotal Study
May 08, 2026
Conditions: Heart Failure; NYHA Class III Heart Failure; NYHA Class II Heart FailureInterventions: Device: IVC Sensor
Sponsors: Foundry Innovation & Research 1, Limited (FIRE1); NAMSA; Baim Institute for Clinical Research
Not yet recruiting
Dietary Interventions in the Secondary Prevention of Myocardial Infarction: Focus on Plant-Based Nutrition
May 08, 2026
Conditions: Myocardial Infarction FirstInterventions: Other: Plant based diet; Other: Diet based on the recommendations of the European Society of Cardiology
Sponsors: Radana Dymáčková; Masaryk University
Completed
The Impact of Preoperative Statin Therapy and and Its Intensity on Postoperative and Mortality and Morbidity
May 08, 2026
Conditions: Perioperative CareSponsors: Karolinska Institutet
Completed
Effects of Two Intervention Programs on Physical Fitness and Quality of Life Among People With Intellectual Disabilities
May 08, 2026
Conditions: Intellectual DisabilitiesInterventions: Behavioral: Traditional physical conditioning; Behavioral: Sport-based individual skills
Sponsors: Universidad Católica San Antonio de Murcia
Enrolling by invitation
CLOT-LESS - CLOsure Tailored: LEss Antithrombotic Strategy After LAAC for Stroke Prevention
May 08, 2026
Conditions: Atrial Fibrillation; Stroke Prevention in Patients With Atrial Fibrillation; Left Atrial Appendage Closure; Hemorrhage; Anticoagulants / Administration & Dosage; Reduced-dose Apixaban; ThromboembolismInterventions: Device: Left Atrial Appendage Closure; Drug: Apixaban 2.5 mg BID; Drug: Standard-dose DOAC
Sponsors: National Medical Research Center for Therapy and Preventive Medicine
Recruiting
North American Fetal Therapy Network Prospective Registry for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia
May 08, 2026
Conditions: Congenital Diaphragmatic HerniaInterventions: Device: Fetoscopic Endoluminal Tracheal Occlusion; Other: Standard of Care
Sponsors: Mayo Clinic
Not yet recruiting
Nursing Intervention for Adaptation After Myocardial Revascularization
May 08, 2026
Conditions: Coronary Artery Disease; Myocardial Revascularization; Postoperative Recovery After Cardiac Surgery; Nursing CareInterventions: Behavioral: Nursing Intervention Program; Other: Usual Care
Sponsors: Universidad de la Sabana
Not yet recruiting
Mindful Movement And GAME BASED Training In Developmental Delay
May 08, 2026
Conditions: Developmental Delay (Disorder)Interventions: Behavioral: Mindful movement; Behavioral: Game based training
Sponsors: Riphah International University
Not yet recruiting
Finerenone in Patients Undergoing Transcatheter Aortic Valve Implantation With Heart Failure
May 08, 2026
Conditions: HFpEF - Heart Failure With Preserved Ejection Fraction; TAVI(Transcatheter Aortic Valve Implantation); FinerenoneInterventions: Drug: Finerenone; Drug: Placebo
Sponsors: Second Affiliated Hospital, School of Medicine, Zhejiang University
Not yet recruiting
Electrophysiological Biomarkers and Treatment Response to Accelerated Transcranial Magnetic Stimulation in Patients With Obsessive-Compulsive Disorder
May 08, 2026
Conditions: Obsessive - Compulsive Disorder; Transcranial Magnetic Stimilation; Intermittent Theta Burst Stimulation; EEGInterventions: Device: iTBS TMS
Sponsors: Istanbul University - Cerrahpasa
Recruiting
Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases
May 08, 2026
Conditions: Congenital Heart Disease; Arrhythmia; Ablation of ArrhythmiasSponsors: Fayoum University
Completed
Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?
May 08, 2026
Conditions: Morbid Obesity Requiring Bariatric SurgerySponsors: University Hospital, Geneva
Recruiting
Quality of Life in Adults With Untreated Fabry Disease in Sweden (QoLUF)
May 08, 2026
Conditions: Fabry DiseaseInterventions: Other: Qualitative Interview
Sponsors: Vastra Gotaland Region; Karolinska University Hospital; Sahlgrenska University Hospital
Not yet recruiting
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
May 08, 2026
Conditions: Depressive Disorder, MajorInterventions: Drug: Seltorexant; Drug: Placebo
Sponsors: Janssen Research & Development, LLC
Recruiting
Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced Heart Failure
May 08, 2026
Conditions: Heart FailureInterventions: Drug: GDMT; Other: Quality of life questionnaire
Sponsors: Università Vita-Salute San Raffaele
Not yet recruiting
Impact of TAVI on the Gut Microbiota and Its Metabolites
May 08, 2026
Conditions: Calcific Aortic Valve Disease; Inflammation; Dysbiosis; TAVISponsors: Insel Gruppe AG, University Hospital Bern; Tours university
Active, not recruiting
Adaptive Digital Exercise Rehabilitation for Children After CHD Surgery
May 08, 2026
Conditions: Congenital Heart Disease (CHD); Congenital Heart Disease in ChildrenInterventions: Behavioral: JITAI-Based Digital Exercise Rehabilitation Program; Behavioral: Standard Exercise Rehabilitation Program
Sponsors: The Children's Hospital of Zhejiang University School of Medicine; Children's Hospital of Nanjing Medical University; Beijing Children's Hospital
Not yet recruiting
The Effect of Music and Musical Mobile Interventions on Pain and Physiological Parameters
May 08, 2026
Conditions: Congenital Heart Disease (CHD); Chest Tube RemovalInterventions: Behavioral: Music Group; Behavioral: Musical Mobile Group
Sponsors: Baskent University
Not yet recruiting
Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease
May 08, 2026
Conditions: COPD; Pulmonary Hypertension; Exercise; Right Ventricular (RV) Dysfunction; Exercise TrainingInterventions: Behavioral: Exercise training
Sponsors: University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting
OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosili-cate in Heart Failure -Extension (OPRA-HF Extension)
May 08, 2026
Conditions: Heart FailureInterventions: Drug: potassium binder
Sponsors: Sahlgrenska University Hospital
Not yet recruiting
Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol
May 08, 2026
Conditions: Hypertension; HypercholesterolemiaInterventions: Drug: Amlodipine; Drug: Ezetimibe/Rosuvastatin; Drug: Ezetimibe/Rosuvastatin Placebo; Drug: Amlodipine Placebo
Sponsors: Celltrion Pharm, Inc.
Completed
Taiwan ED Airway Quality Surveillance Registry (TEAR)
May 08, 2026
Conditions: Airway Management; Tracheal Intubation; Emergency Department; Peri-intubation Adverse EventsSponsors: Chang Gung Memorial Hospital
Not yet recruiting
Outcomes of an Optimized Workflow With PulseSelect Pulsed Field Ablation (PFA) System in Paroxysmal and Persistent Atrial Fibrillation
May 08, 2026
Conditions: Paroxysmal Atrial Fibrillation (PAF); Persistent Atrial FibrillationInterventions: Device: PulseSelect Pulse Field Ablation (PFA) System
Sponsors: Medtronic Cardiac Ablation Solutions
Not yet recruiting
Home Monitor for AA Burden Detection IIT in TWN
May 07, 2026
Conditions: Paroxysmal Atrial Fibrillation (PAF); Atrial FlutterSponsors: National Taiwan University Hospital; Biotronik SE & Co. KG
Not yet recruiting
Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults
May 07, 2026
Conditions: Frailty Syndrome; Older Adults; Blood Flow Restriction (BFR) Training Effects; Inspiratory Muscle TrainingInterventions: Behavioral: Exercise; Behavioral: Sham Control
Sponsors: Taipei Medical University; National Taiwan University; The University of Texas at Austin
Not yet recruiting
Dynamic Voltage Mapping to Personalise the Ventricular Tachycardia Substrate
May 07, 2026
Conditions: Ventricular Tachycardia (VT)Interventions: Procedure: Dynamic Voltage Mapping; Procedure: Standard of Care Ablation
Sponsors: Liverpool Heart and Chest Hospital NHS Foundation Trust
Not yet recruiting
tDCS and the Cardiovascular System in Community-dwelling Elderly.
May 07, 2026
Conditions: Community-dwelling ElderlyInterventions: Other: tDCS; Other: Sham stimulation
Sponsors: Riphah International University
Not yet recruiting
Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot Study
May 07, 2026
Conditions: Heart Failure Due to Coronary Artery Disease; Valvular Cardiomyopathy; Heart FailureInterventions: Drug: Sacubitril / Valsartan; Drug: SGLT-2 inhibitor; Drug: Sacubitril / Valsartan; Drug: SGLT2 Inhibition
Sponsors: Kyungsub Song; Seoul National University Bundang Hospital; Korea University Anam Hospital; Ajou University Medical Center
Not yet recruiting
Improving Insulin Sensitivity in Patients With Type 2 Diabetes Via Repeated Cold-induced Shivering Thermogenesis
May 07, 2026
Conditions: Type 2 DiabetesInterventions: Behavioral: Cold exposure with shivering
Sponsors: Université de Sherbrooke; Maastricht University Medical Center
Recruiting
Abdominal Aortic Tourniquet Application for Non-Traumatic Out-of-Hospital Cardiac Arrest
May 07, 2026
Conditions: Cardiac Arrest (CA); Out-of-hospital Cardiac Arrest (OHCA); Asystole; Pulseless Electrical Activity; Ventricular FibrillationInterventions: Device: Abdominal Aortic Junction Tourniquet in non-traumatic out-of-hospital cardiac arrest
Sponsors: Klinikum Klagenfurt am Wörthersee
Not yet recruiting
Function of Beta Cells in Early-onset Diabetes Mellitus
May 07, 2026
Conditions: Type 2 Diabetes Mellitus (T2DM); Beta Cell FunctionInterventions: Other: Monitor and observe the clinical progression and beta cell function
Sponsors: University Medical Center Ho Chi Minh City (UMC)
Recruiting
Advanced Imaging to Assess the Effect of Immunosuppression on Progressive Fibrosis
May 07, 2026
Conditions: Interstitial Lung Disease; Pulmonary FibrosisInterventions: Drug: [68Ga]CBP8; Drug: Gadoterate Meglumine
Sponsors: Peter Caravan; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting
Sleep, Stress and Migraine - an Observational and Training Study
May 07, 2026
Conditions: Migraine; Sleep Disorder (Disorder); Stress; Migraine in AdultsInterventions: Behavioral: Profile-based behavioral sleep and stress management
Sponsors: Susanne Wegener
Recruiting
Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 Diabetes
May 07, 2026
Conditions: Type 1 Diabetes; OverweightInterventions: Other: Exercise training
Sponsors: University of Virginia
Recruiting
ECG and CXR for Predicting Cardiovascular Diseases
May 07, 2026
Conditions: Valvular Heart Diseases; Valvular Heart Disease Stenosis and Regurgitation; Regurgitation, Aortic Valve; Regurgitation, MitralSponsors: Shanghai Zhongshan Hospital
Completed
Preliminary Efficacy of a Remote Cardiac Rehabilitation Program in Pediatric Patients With Complex Congenital Heart Disease
May 07, 2026
Conditions: Complex Congenital Heart DiseaseInterventions: Behavioral: Community-Based Remote Cardiac Rehabilitation Program; Behavioral: standard of care
Sponsors: Seoul National University Hospital; University of Seoul
Recruiting
Tissue Doppler Echocardiographic Assessment of Cardiac Function in Neonatal Sepsis
May 07, 2026
Conditions: Neonatal Sepsis, MarkersInterventions: Diagnostic Test: cardiac troponin, and blood culture
Sponsors: Assiut University
Not yet recruiting
Virtual Lifestyle Intervention for Weight Management and Cardiovascular Heal
May 07, 2026
Conditions: Cardiovascular Risk FactorInterventions: Behavioral: Multicomponent Virtual Lifestyle Intervention
Sponsors: Truemedicine Inc
Enrolling by invitation
Effect of vitk2 on Atopic Dermatitis Pediatrics Patients
May 07, 2026
Conditions: Atopic DermatitisInterventions: Dietary Supplement: vit k2; Other: Placebo
Sponsors: October 6 University
Completed
Use of Various Types of Introducers in Conventional Radial Access
May 07, 2026
Conditions: Percutaneous Coronary Intervention (PCI); Radial Artery Occlusion; Radial Artery SpasmInterventions: Procedure: catheterization of the radial artery using an classic introducer; Procedure: catheterization of the radial artery using an introducer with a standard outer diameter and an outer hydrophilic coating; Procedure: catheterization of the radial artery using an introducer with a reduced outer diameter and an outer hydrophilic coating
Sponsors: Pirogov Russian National Research Medical University; I.M. Sechenov First Moscow State Medical University
Completed
A Study of Using CARTO SOUND™ FAM to Guide Pulsed Field Ablation for Atrial Fibrillation
May 07, 2026
Conditions: Atrial FibrillationInterventions: Device: CARTO SOUND™ FAM System with Varipulse™ PFA Catheter
Sponsors: China National Center for Cardiovascular Diseases; Central China Fuwai Hospital of Zhengzhou University; The Affiliated Hospital of Qingdao University
Not yet recruiting
Normative Values For Physical Fitness
May 07, 2026
Conditions: Healthy AdultsSponsors: Riphah International University
Enrolling by invitation
The Effects of Low-Flow and Normal-Flow Sevoflurane Anesthesia on Frontal QRS-T Angle and TP-e Interval
May 07, 2026
Conditions: Cardiac Arrhythmia; AnesthesiaInterventions: Procedure: low flow anesthesia
Sponsors: Istanbul University
Not yet recruiting
Additional Effect of Coherent Breathing With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals
May 07, 2026
Conditions: Stage 1 HypertensivesInterventions: Other: Coherent Breathing.; Other: Aerobic Exercises
Sponsors: Foundation University Islamabad
Recruiting
Effects of E-care Protocol in Patients With Coronary Artery Bypass Graft
May 07, 2026
Conditions: CABGInterventions: Device: IMT Threshold device
Sponsors: Riphah International University
Not yet recruiting
Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?
May 07, 2026
Conditions: Post-menopauseInterventions: Dietary Supplement: Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
Sponsors: Western Norway University of Applied Sciences
Recruiting
Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn Patients
May 07, 2026
Conditions: Burn InjuryInterventions: Device: Non-Invasive Vagus Nerve Stimulation; Other: Conventional Physiotherapy
Sponsors: Fenerbahce University
Enrolling by invitation
Sotagliflozin as Prevention of Anthracycline-Related Cardiotoxicity
May 07, 2026
Conditions: Anthracycline-induced Cardiotoxicity; Lymphoma; Chemotherapy; CardiotoxicityInterventions: Drug: Sotagliflozin; Drug: Placebo
Sponsors: Icahn School of Medicine at Mount Sinai; American Heart Association
Not yet recruiting
WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department
May 07, 2026
Conditions: Acute Hypoxic Respiratory Failure; Acute Respiratory Distress Syndrome (ARDS)Interventions: Device: Non-Invasive Positive Pressure Ventilation; Device: High Flow Nasal Oxygen
Sponsors: Ohio State University; National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Medical University of South Carolina; University of Arizona; Baystate Medical Center
Not yet recruiting
Restoring Sinus Rhythm Using Dual-Shock Technique in Patients With Atrial Fibrillation
May 07, 2026
Conditions: Atrial Fibrillation (AF); Atrial FibrillationInterventions: Procedure: Conventional Electrical Cardioversion; Procedure: Dual-shock Electrical Cardioversion
Sponsors: Martín Negreira Caamaño
Not yet recruiting
The Application of Biomarkers in the Care of Patients With Atrial Fibrillation
May 07, 2026
Conditions: Atrial Fibrillation; BiomarkerSponsors: National Taiwan University Hospital
Withdrawn
Pemafibrate for Symptomatic ICAS RCT
May 07, 2026
Conditions: Intracranial Atherosclerotic Disease (ICAD); Hypertriglyceridaemia; Stroke (CVA) or TIAInterventions: Drug: Pemafibrate
Sponsors: Tokyo Women's Medical University; Kowa Company, Ltd.
Not yet recruiting
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
May 07, 2026
Conditions: Heart Failure; Prefrail Elderly; Frail Elderly SyndromeInterventions: Behavioral: Telerehabilitation; Behavioral: Caregiver-Supervised Home Exercise Program
Sponsors: University of Salerno; Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Not yet recruiting
Effect of Non-Invasive Vagus Nerve Stimulation in Burn Patients
May 07, 2026
Conditions: Burn InjuryInterventions: Device: Non-Invasive Vagus Nerve Stimulation; Other: Conventional Physiotherapy
Sponsors: Fenerbahce University
Enrolling by invitation
Exercise Training After Upper Gastrointestinal Cancer Surgery
May 07, 2026
Conditions: Esophageal Cancer; Gastric Cancer (Diagnosis); Upper Gastrointestinal CancerInterventions: Behavioral: High-Intensity Interval Training (HIIT); Behavioral: Low-Intensity Continuous Training (LICT)
Sponsors: Kansai Medical University
Not yet recruiting
Stress and Menstrual Health
May 07, 2026
Conditions: Menstrual DysfunctionInterventions: Other: Heat stress; Other: Sleep stress; Other: Exercise stress
Sponsors: Duke University
Not yet recruiting
Evaluation of Probiotics' Effect on Atrial Fibrillation Recurrence in Patients Undergoing Cardioversion
May 06, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Drug: Anticoagulant Therapy; Drug: Probiotics capsules
Sponsors: Ain Shams University
Not yet recruiting
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes
May 06, 2026
Conditions: Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite AthletesInterventions: Drug: Testosterone Enanthate; Drug: Testosterone Cypionate; Drug: Testosterone Propionate; Drug: Sustanon (testosterone); Drug: Testosterone Gel; Drug: Methenolone Enanthate (Primobolan); Drug: Nandrolone Decanoate (Deca-Durabolin); Drug: Estradiol Patch; Drug: Estradiol Capsule; Drug: Progesterone Cream; Drug: Progesterone Capsule; Drug: Human Growth Hormone (hGH); Drug: EPO Darbepoetin (Aranesp); Drug: Meldonium; Drug: Modafinil; Drug: Mixed amphetamine salts (Adderall); Drug: Clomiphene; Drug: Anastrozole; Drug: Levothyroxine; Drug: Liothyronine; Drug: hCG; Drug: hMG; Drug: Atorvastatin; Drug: Rosuvastatin; Drug: Bisoprolol; Drug: Nebivolol; Drug: Metoprolol; Drug: Propranolol; Drug: Lisinopril; Drug: Enalapril; Drug: Furosemide; Drug: Chlorothiazide; Drug: Cabergoline; Drug: Metformin; Drug: Basal Insulin Glargine (long-acting); Drug: Telmisartan; Drug: Losartan
Sponsors: Enhanced Emirates Limited
Enrolling by invitation
A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery
May 06, 2026
Conditions: Coronary Artery Disease; Atrial FibrillationInterventions: Drug: Liposomal bupivacaine; Drug: Placebo
Sponsors: Mayo Clinic
Not yet recruiting
AUTONOMOUS DISORDERS IN CMT
May 06, 2026
Conditions: CMT - Charcot-Marie-Tooth Disease; CMT1A; CMT (Charcot Marie Tooth Disease)Sponsors: University Medical Center Goettingen
Recruiting
Using Mirabegron to Control Arrhythmia-1
May 06, 2026
Conditions: Ventricular Arrhythmias and Cardiac ArrestInterventions: Drug: Mirabegron
Sponsors: Cedars-Sinai Medical Center
Not yet recruiting
Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL
May 06, 2026
Conditions: Mantle Cell Lymphoma (MCL)Interventions: Biological: zamtocabtagene autoleucel (MB-CART2019.1); Drug: Cyclophosphamide; Drug: Fludarabine
Sponsors: Miltenyi Biomedicine GmbH; National Heart, Lung, and Blood Institute (NHLBI); National Cancer Institute (NCI)
Not yet recruiting
HFrEF Polypill in Sri Lanka RCT
May 06, 2026
Conditions: Heart Failure With Reduced Ejection FractionInterventions: Other: Comparator Arm; Drug: HFrEF Polypill
Sponsors: Washington University School of Medicine; The George Institute; Centre for Chronic Disease Control, India; National Heart, Lung, and Blood Institute (NHLBI); RemediumOne
Not yet recruiting
Physical Activity Maintenance Intervention for People With Stroke
May 06, 2026
Conditions: StrokeInterventions: Other: Physical activity maintenance
Sponsors: University of Ulster; Northern Ireland Chest Heart and Stroke
Active, not recruiting
LEXURE for Post-Stroke Aphasia: A Randomized, Evaluator-Blinded, Confirmatory Trial
May 06, 2026
Conditions: AphasiaInterventions: Device: LEXURE; Behavioral: Workbook
Sponsors: Nunaps Inc
Recruiting
Online Personalized Psychological Intervention for Patients With Heart Disease and Depression or Anxiety (MY-CHOICE)
May 06, 2026
Conditions: Ischemic Heart Disease (IHD); Anxiety; DepressionInterventions: Other: Online psychological therapy
Sponsors: University of Southern Denmark; Aarhus University Hospital Skejby; Aalborg University Hospital; Zealand University Hospital
Recruiting
Clinical Validation of Portable Electronic Stethoscope for Detecting VHD
May 06, 2026
Conditions: Heart Valve DiseasesInterventions: Device: BPM Core
Sponsors: The University of Hong Kong
Recruiting
Effect of a Visual Educational Intervention on Dental Anxiety in Children
May 06, 2026
Conditions: Dental Anxiety in ChildrenInterventions: Behavioral: Visual Educational Leaflet
Sponsors: Istanbul University
Completed
Digitally Enhanced Cognitive-Behavioral Therapy
May 06, 2026
Conditions: Depression in Adolescence; Obesity & Overweight; Cognitive-behavioral Therapy; Mobile Health Technology (mHealth); Health BehaviorInterventions: Behavioral: Cognitive-behavioral therapy (CBT); Behavioral: Digital app
Sponsors: Colorado State University; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Intraoperative Application of Cold Atmospheric Plasma to Prevent Postoperative Wound Complications in the Inguinal Region of High-risk Patients With Peripheral Arterial Occlusive Disease
May 06, 2026
Conditions: Peripheral Occlusive Disease; Wound Healing; Wound Healing Complication; Cold Atmospheric Plasma; PreventionInterventions: Device: Cold atmospheric plasma; Device: Sham device
Sponsors: Ursula Werra; neoplas med GmbH; Universitätsklinikum Hamburg-Eppendorf
Not yet recruiting
Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness
May 06, 2026
Conditions: Major Depressive Disorder (MDD); Anxiety Disorder; Alcohol Use Disorder (AUD)Interventions: Device: wearable monitoring devices
Sponsors: Huashan Hospital
Not yet recruiting
Promoting Walking Among Older Adults Through Nostalgia-Based Messages and Step-Monitoring
May 06, 2026
Conditions: Walking; Older Adults (65 Years and Older); Messaging; Mobile Applications; Reminder Systems; Psychosocial Factors; Psychosocial Effects and Treatment; Physical Activity Promotion; Health Behaviour; Functional Decline; Aging ProblemsInterventions: Behavioral: Nostalgia-based messages promoting walking; Behavioral: Step-monitoring reminders promoting walking; Behavioral: Messages about water intake benefits; Behavioral: Nostalgia-based messages & Step-monitoring reminders promoting walking
Sponsors: Catholic University, Italy; IPSOS
Not yet recruiting
Point of Care Testing INR in Antiphospholipid Syndrome
May 06, 2026
Conditions: Antiphospholipid Syndrome; Vitamine K Antagonist (VKA) TreatmentInterventions: Device: Coaguchek
Sponsors: Central Hospital, Nancy, France
Not yet recruiting
Feasibility, Acceptability, and Safety Trial of Brief, Breath Control-Focused Acceptance and Commitment Therapy in Adults With Chronic Cough
May 06, 2026
Conditions: Chronic CoughInterventions: Behavioral: Acceptance and Commitment Therapy (ACT)
Sponsors: University of North Carolina, Chapel Hill; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
May 06, 2026
Conditions: Atrial Fibrillation; Electric Countershock; Deep SedationInterventions: Drug: BIS-guided propofol sedation; Drug: Clinical-guided propofol sedation
Sponsors: Istanbul University - Cerrahpasa
Not yet recruiting
Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic Shock
May 06, 2026
Conditions: Septic Shock, Vasopressor ResistanceInterventions: Drug: Dexmedetomidine 100 µg/mL, intravenous solution; Other: Stardard care
Sponsors: Hospices Civils de Lyon; Centre Hospitalier Universitaire Dijon
Not yet recruiting
Cardiologist-Administered Midazolam vs. Anaesthesiologist-Assisted Propofol Sedation For Transoesophageal Echocardiography-Guided Cardioversion of Atrial Fibrillation
May 06, 2026
Conditions: Atrial Fibrillation (AF); Atrial FlutterInterventions: Other: One-step cardiologist-only midazolam sedation; Other: Two-step anaesthesiologist-assisted propofol sedation
Sponsors: Gødstrup Hospital; University of Aarhus
Not yet recruiting
Low-dose Colchicine for CABG Graft Failure Prevention
May 06, 2026
Conditions: CAD - Coronary Artery Disease; CABG; ColchicineInterventions: Drug: Colchicine Pill; Drug: Placebo
Sponsors: Beijing Anzhen Hospital
Not yet recruiting
Overviewing Real-World Outcomes to Boost Interventional Management of CAlcified Coronary Lesions: the OROBICA Registry.
May 06, 2026
Conditions: Coronary Artery Disease (CAD); Calcific Coronary Arteriosclerosis; Intravascular Lithotripsy; Rotational Atherectomy; OFDI; Orbital Atherectomy; Optical Coherence Tomography (OCT); Intravascular Ultrasound; Percutaneous Coronary InterventionInterventions: Procedure: Percutaneous coronary intervention with or without stent implantation
Sponsors: Papa Giovanni XXIII Hospital
Not yet recruiting
Spanish Prospective Registry of Hydra THV for Transcatheter Aortic Valve Implantation
May 05, 2026
Conditions: Severe Aortic Valve Stenosis; Valvular Heart Disease; Aortic Valve StenosisInterventions: Device: Hydra THV
Sponsors: Fundación EPIC
Not yet recruiting
Measuring Absolute Brain Flow and Brain Microcirculation Resistance by Continuous Thermodilution: a Pilot Study
May 05, 2026
Conditions: Ischemic StrokeInterventions: Device: Measuring Absolute Cerebral Flow and Microvascular Resistance by Thermodilution
Sponsors: Centre Hospitalier Universitaire de Nice
Recruiting
Women With Previous GDM and the Effects of HIIT.
May 05, 2026
Conditions: Gestational Diabetes Mellitus (GDM); Type 2 Diabetes (T2DM); High-intensity Interval TrainingInterventions: Other: High-intensity interval training
Sponsors: Odense University Hospital; University of Southern Denmark
Enrolling by invitation
Correlation of Cardiac Index Measured by the PRAM Method With NIRS and Lactate Levels in Pediatric Aortic Coarctation Surgery
May 05, 2026
Conditions: Aortic Coarctation; Cardiac Output, LowInterventions: Device: MostCare (PRAM); Device: Near-Infrared Spectroscopy (NIRS); Procedure: Arterial Blood Gas with Lactate
Sponsors: Konya City Hospital
Not yet recruiting
Non-stenting Treatment Strategy for Acute Myocardial Infarction With Non-severe Stenosis(EROSION IV)
May 05, 2026
Conditions: Acute Myocardial Infarction (AMI); ST-Segment Elevation Myocardial Infarction(STEMI); Non-ST-Segment Elevation Myocardial Infarction(NSTEMI)Interventions: Drug: Guideline-recommended standard medical therapy alone; Procedure: DES implantation plus guideline-recommended standard medical therapy
Sponsors: Harbin Medical University
Not yet recruiting
Endocrinal Dysfunction Among Children With Dilated Cardiomyopathy
May 05, 2026
Conditions: Assessment of Some Hormone Levels in Children With Dilated CardiomyopathyInterventions: Diagnostic Test: Echocardiography assessment.; Diagnostic Test: Laboratory investigations and Hormone assessment.
Sponsors: Sohag University
Not yet recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
May 05, 2026
Conditions: Obesity; Heart FailureInterventions: Drug: NNC0487-0111; Drug: Placebo
Sponsors: Novo Nordisk A/S
Not yet recruiting
Early Detection of Concealed Cardiac Amyloidosis Using AI-ECG and CT-Derived Extracellular Volume in Patients With Atrial Fibrillation
May 05, 2026
Conditions: Atrial Fibrillation (AF); Cardiac AmyloidosisInterventions: Diagnostic Test: AI-ECG analysis; Diagnostic Test: CT-ECV analysis; Other: Atrial fibrillation treatment
Sponsors: Samsung Medical Center; Mayo Clinic
Not yet recruiting
Impact of Transcatheter Patent Ductus Arteriosus Closure on Left Atrial and Ventricular Remodeling in Adults and Adolescents.
May 05, 2026
Conditions: Patent Ductus ArteriosesInterventions: Procedure: Transcatheter Patent Ductus Arteriosus Closure
Sponsors: Emil Magdy Badry
Not yet recruiting
Efferon LPS Hemoadsorption in in Patients With Thermal Burns
May 05, 2026
Conditions: BurnsInterventions: Device: Efferon LPS
Sponsors: Efferon JSC
Not yet recruiting
ADAI - Home Care in Intelligent Environments Clinical Care Ecosystem for the Management of Home Digital Therapies Through the Use of Assistive Robots and Clinical Predictive Systems Based on Artificial Intelligence Systems
May 05, 2026
Conditions: Neurodegenerative Disease; Artificial Intelligence (AI); Mild Cognitive Impairment (MCI)Interventions: Device: CLINICAL INVESTIGATION WITH A MEDICAL DEVICE MARKED CE
Sponsors: IRCCS Centro Neurolesi Bonino Pulejo
Completed
Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance
May 05, 2026
Conditions: Septic Shock; Cirrhosis; Vasodilatory Shock; Acute Kidney InjuryInterventions: Drug: Giapreza
Sponsors: The Cleveland Clinic; Innoviva Specialty Therapeutics
Active, not recruiting
Evaluation of the Systemic Microcirculation as a Surrogate for Coronary Microcirculation in Women With ANOCA
May 05, 2026
Conditions: Angina, MicrovascularInterventions: Procedure: Investigation of Systemic Endothelial Microvascular Function
Sponsors: National Institute of Cardiology, Laranjeiras, Brazil
Not yet recruiting
Reminder Strategies to Improve Meal-Logging Adherence
May 05, 2026
Conditions: Patient Compliance; Mobile Applications; Reminder SystemsInterventions: Behavioral: Loss-Framed Reminder; Behavioral: Logging Consistency Reminder; Behavioral: Neutral Reminder
Sponsors: University of St.Gallen
Recruiting
Night-to-Night Variability of Novel Physiological Parameters in Home Sleep Apnea Testing
May 05, 2026
Conditions: Obstructive Apnea; Diagnostic; Sleep Apnea Syndrome (OSAS)Sponsors: Insel Gruppe AG, University Hospital Bern
Not yet recruiting
Implementation of an Accessible Healthcare Model (ACHD STRONG): Comparing Nurse and Physician Lead Healthcare Transition Education in a RE-AIM Framework
May 05, 2026
Conditions: Congenital Heart DiseaseInterventions: Other: Accessible Care Model Visit; Other: Recruitment Interviews; Other: Participating Patient-Support Person Interviews; Other: Participating Patient-Support Person Surveys; Other: Participating Provider Interviews and surveys; Other: Unstructured and semi-structured interviews
Sponsors: University of Wisconsin, Madison
Recruiting
PollenVax Subcutaneous Immunotherapy for Mugwort Pollen-Induced Allergic Rhinitis
May 04, 2026
Conditions: Rhinitis AllergicInterventions: Biological: Recombinant Artemisia vulgaris allergen Art v 1 with Montanide ISA-51 adjuvant; Biological: Montanide ISA-51 placebo emulsion
Sponsors: Kazakh National Agrarian University
Not yet recruiting
PROMab Trial: Ampicillin With or Without Gentamicin for Term Prelabour Rupture of Membranes
May 04, 2026
Conditions: Rupture of Membranes Prior to Onset of LaborInterventions: Drug: Ampicillin; Drug: Ampicillin + gentamicin
Sponsors: Sarawak General Hospital
Not yet recruiting
Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer
May 04, 2026
Conditions: Platinum-Sensitive Ovarian Cancer; Ovarian CancerInterventions: Biological: Rina-S; Drug: Bevacizumab; Drug: Carboplatin; Drug: Gemcitabine; Drug: Paclitaxel; Drug: PLD
Sponsors: Genmab
Not yet recruiting
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Serum Magnesium Levels
May 04, 2026
Conditions: Dialysis; ComplicationsInterventions: Device: A - Dialysate magnesium 0.75; Device: B - Dialysate magnesium 1.00 mmol/L
Sponsors: Universitaire Ziekenhuizen KU Leuven; Fresenius AG
Completed
100-Year Human Aging Study
May 04, 2026
Conditions: Aging; Aging Well; All-Cause Mortality; Mortality; Metabolic Syndrome; Cardiovascular Diseases; Cognitive Dysfunction; Musculoskeletal Diseases; Neoplasms; Frailty; Activities of Daily Living; Health-Related Quality of Life; Disability Physical; Neuro-Degenerative Disease; DementiaInterventions: Diagnostic Test: Comprehensive Multi-System Clinical Screening
Sponsors: Longevity Metrics, Inc.
Recruiting
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
May 04, 2026
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy; FAPI PET; Cardiac Magnetic Resonance ImagingInterventions: Diagnostic Test: 68Ga-DOTA-SA-FAPI PET/CT
Sponsors: Istanbul University - Cerrahpasa
Recruiting
Phase II Study of Ultrasound and ctDNA Guided Neoadjuvant Systemic Therapy for Patients With HER2-positive Early Breast Cancer (UC HER Trial)
May 04, 2026
Conditions: HER-2 Positive Breast CancerInterventions: Drug: Lipo-Dox®; Drug: Cyclophosphamide; Drug: Trastuzumab (Herceptin); Drug: Pertuzumab
Sponsors: National Taiwan University Hospital; TTY Biopharm
Not yet recruiting
Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation
May 04, 2026
Conditions: Phantom Limb Pain; Neuropathic Pain; Lower Limb AmputationInterventions: Drug: Hyperbaric Bupivacaine plus Saline; Drug: Hyperbaric Bupivacaine plus Dexmedetomidine
Sponsors: Universidad Juárez Autónoma de Tabasco
Completed
Prevalence, Pathogenesis, and Prognosis of Pulmonary Hypertension in Dialysis Patients
May 04, 2026
Conditions: Pulmonary HypertensionSponsors: Fondazione IRCCS Policlinico San Matteo di Pavia
Recruiting
Hyperthermia Safety Study Uses Temperature Management System to Gently Raise Participant's Body Temperature to a Fever-range Level in a Controlled Setting.
May 04, 2026
Conditions: Safety StudyInterventions: Other: Hyperthermia
Sponsors: Marc Abreu
Enrolling by invitation
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
May 04, 2026
Conditions: Obesity; Type 2 DiabetesInterventions: Drug: Cagrisema; Drug: Semaglutide
Sponsors: Novo Nordisk A/S
Not yet recruiting
Drug-Drug Interactions of JMKX003142 in Healthy Participants
May 04, 2026
Conditions: ADPKD (Autosomal Dominant Polycystic Kidney Disease)Interventions: Drug: JMKX003142 tablets; Drug: Fluconazole Capsules; Drug: Cocktail Substrates (Midazolam Oral Solution, Rosuvastatin Calcium Tablets, and Digoxin Tablets); Drug: Cyclosporine Soft Capsules; Drug: Omeprazole Enteric-coated Tablets; Drug: Efavirenz Tablets; Drug: JMKX003142 tablets; Drug: JMKX003142 tablets; Drug: JMKX003142 tablets
Sponsors: Jemincare; Zhejiang Hangyu Pharmaceutical Co., Ltd.
Not yet recruiting
Comparison of 7-Day ECG Patches
May 04, 2026
Conditions: Atrial Fibrillation (AF); Cardiac ArrhythmiasInterventions: Device: Smartcardia 7L Patch; Device: ECG247; Device: HeartX Recorder; Device: Kardiobeat; Device: net_ECG; Device: ZIO Patch
Sponsors: Medical University Innsbruck
Active, not recruiting
PREDICTING MINS WITH FRAILTY AND BIOMARKERS IN GERIATRIC SURGERY
May 04, 2026
Conditions: Geriatric Patients; Postoperative Complications; Frailty; Myocardial Ischemia; Hip SurgeriesInterventions: Other: Preoperative Risk Assessment and Machine Learning Modeling
Sponsors: DİLEK KALAYCI
Active, not recruiting
Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment Elevation
May 04, 2026
Conditions: Myocardial Infarction (MI); Acute Coronary Syndromes (ACS)Interventions: Diagnostic Test: Prehospital high-sensitivity cardiac troponin I measurement
Sponsors: Central Denmark Region
Not yet recruiting
A Pre-market, Two-stages Interventional Clinical Investigation to Evaluate the Safety and the Performance of Fibroin Syrup in Reducing the Gastroesophageal Reflux Disease (GERD) Symptomatology in Nonerosive Reflux Disease (NERD) Patients
May 04, 2026
Conditions: GERD (Heartburn, Regurgitation, and Dyspepsia); Gastroesophageal Reflux (GERD)Interventions: Device: Syrup made by hyaluronic acid
Sponsors: Rose Pharma SA
Completed
Changes in Intramyocardial Fat Assessed by Cardiac CT Before and After Bariatric Surgery and Their Relationship With Cardiac Diastolic Function
May 04, 2026
Conditions: Obesity; Diastolic Dysfunction; Heart Failure With Preserved Ejection Fraction (HFPEF)Sponsors: Itshak Amsalem
Not yet recruiting
Association Between Sarcopenia, Fatigue and Orthostatic Intolerance in Geriatric Patients: A Case Control Study
May 04, 2026
Conditions: Sarcopenia; Fatigue; Orthostatic IntoleranceSponsors: Ain Shams University
Not yet recruiting
Leveraging Extended Reality Exergaming and Telehealth to Improve Physical Activity and Health in Children With Disabilities
May 04, 2026
Conditions: Cerebral Palsy (CP)Interventions: Behavioral: Extended Reality Exergaming
Sponsors: University of Alabama at Birmingham
Not yet recruiting
Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome
May 04, 2026
Conditions: Erectile Dysfunction; Left Ventricular Diastolic Dysfunction; Metabolic SyndromeInterventions: Drug: Tadalafil 5 mg; Drug: SGLT-2 inhibitor; Drug: Tadalafil plus SGLT2 inhibitors
Sponsors: Kafrelsheikh University
Completed
Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis
May 04, 2026
Conditions: Atherosclerotic Renal Artery Stenosis; Hypertension; Renal Artery StenosisInterventions: Device: Covered Stent; Device: Bare Metal Stent
Sponsors: Chinese Academy of Medical Sciences, Fuwai Hospital
Not yet recruiting
Breathing Exercises During Labor and Maternal Outcomes
May 04, 2026
Conditions: Labor Pain; Anxiety; Stress, PsychologicalInterventions: Behavioral: Guided Breathing Exercises During Labor
Sponsors: Nilgun Avci
Completed
Physical Activity Directly Before Immunotherapy (Nivolumab and Ipilimumab) in Melanoma
May 04, 2026
Conditions: Metastatic MelanomaInterventions: Behavioral: 30 Minutes Cycle Ergometer
Sponsors: Universitätsklinikum Hamburg-Eppendorf
Recruiting
PAIN AFTER CARDIAC ARREST AND RESUSCITATION
May 04, 2026
Conditions: Out of Hospital Cardiac Arrest; PainSponsors: Region Skane
Recruiting
Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension
May 04, 2026
Conditions: Pulmonary HypertensionInterventions: Dietary Supplement: Nicotinamide Riboside (NR); Drug: Placebo
Sponsors: Vanderbilt University Medical Center; National Heart, Lung, and Blood Institute (NHLBI)
Recruiting
Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers
May 04, 2026
Conditions: Coronary Artery DiseaseInterventions: Device: Sirolimus-Ascorbic Acid Eluting Stent; Device: Everolimus-Eluting Stent
Sponsors: Jung-min Ahn; The CardioVascular Research Foundation (CVRF)
Not yet recruiting
Incretin Therapies in Obesity-related HFpEF
May 04, 2026
Conditions: Heart Failure, Diastolic; Heart Failure With Preserved Ejection Fraction; ObesityInterventions: Drug: Tirzepatide
Sponsors: Columbia University
Not yet recruiting
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
May 04, 2026
Conditions: Cardiovascular Surgical Procedures; Pain, Postoperative; Cardiovascular DiseasesInterventions: Procedure: Ultrasound-Guided Pectointercostal Fascial Plane Block; Procedure: Ultrasound-Guided Rectus Sheath Block; Procedure: Ultrasound-Guided Recto-Intercostal Fascial Plane Block
Sponsors: Ordu University
Recruiting
ABLUMINUS NP Polymer Free Sirolimus-Eluting Stent Registry at Geneva University Hospitals (ABLUMINUS-GVA)
May 01, 2026
Conditions: Coronary Artery Disease; Acute Coronary Syndrome; Myocardial Infarction; Stent Thrombosis; Percutaneous Coronary InterventionInterventions: Device: ABLUMINUS NP polymer-free sirolimus-eluting stent
Sponsors: Dorian Garin
Not yet recruiting
Prognostic Impact of Diabetes and Weight Variability in Telemonitored Heart Failure
May 01, 2026
Conditions: Chronic Heart Failure; Type 2 Diabetes; Diabetes (DM)Interventions: Other: Diabetes Status; Other: Comorbidity Burden; Other: Weight variability
Sponsors: Satelia
Completed
Inhaled DMT for Major Depressive Disorder
May 01, 2026
Conditions: MDD; Major Depressive Disorder (MDD); Major Depression; Suicidal Ideation; SuicideInterventions: Drug: N,N-Dimethyltryptamine (15 mg + 60 mg); Drug: N,N-Dimethyltryptamine (1 mg + 4 mg)
Sponsors: Universidade Federal do Rio Grande do Norte; Financiadora de Estudos e Projetos
Not yet recruiting
The Salt Study for Heart Failure
May 01, 2026
Conditions: Heart FailureInterventions: Other: Normal Salt Diet; Other: Cardiac Diet
Sponsors: Maya Guglin, MD
Recruiting
THE EFFECTS OF VIRTUAL ART THERAPY ON PHYSIOLOGICAL PARAMETERS, DELIRIUM RISK, ANGER, ANXIETY, AND MENTAL AND SPIRITUAL RECOVERY IN INTENSIVE CARE PATIENTS.
May 01, 2026
Conditions: Delirium Risk; Critical Illness in Coronary ICU Patients; Mental and Spiritual Recovery; Effects of Virtual Art TherapyInterventions: Other: Virtual Art Therapy
Sponsors: Inonu University
Not yet recruiting
The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease
May 01, 2026
Conditions: Pulmonary Hypertension; Interstitial Lung DiseaseInterventions: Behavioral: Home Exercise Program, Aerobic Plus Strength Training; Behavioral: Home Exercise Program, Aerobic Only
Sponsors: University of Rochester; Liquidia Technologies, Inc.
Not yet recruiting
Impact of Optimized Pacing Strategies on Clinical and Hemodynamic Outcomes in Heart Failure Patients With Pacemaker
May 01, 2026
Conditions: Heart Failure; BradycardiaInterventions: Procedure: Adjustment of the pacemaker/ICDs lower rate limit (LRL); Procedure: Conventional lower rate (60bpm)
Sponsors: Samsung Medical Center
Recruiting
Effects of High-frequency Left Dorsolateral Prefrontal rTMS on Heart-brain Coupling in Women With Recurrent Pregnancy Loss and Elevated BMI
May 01, 2026
Conditions: Recurrent Pregnancy Loss; Overweight , Obesity; Heart-Brain CouplingInterventions: Device: Real repetitive transcranial magnetic stimulation; Device: Sham repetitive transcranial magnetic stimulation
Sponsors: Shenyang Medical College
Not yet recruiting
Assessment of Left Atrial Size and Function by Cardiac Magnetic Resonance
May 01, 2026
Conditions: Cardiac Magnetic ResonanceInterventions: Diagnostic Test: CMR scan
Sponsors: Istituto Auxologico Italiano
Completed
The Effect of a Single Intravenous Injection of Esketamine During Cesarean Section on Postoperative Pruritus in Patients With Intrahepatic Cholestasis of Pregnancy
May 01, 2026
Conditions: Intrahepatic Cholestasis of PregnancyInterventions: Drug: Normal Saline (0.9% NaCl); Drug: Esketamine 0.3mg/kg
Sponsors: Tianjin Medical University General Hospital
Not yet recruiting
Improving Health Outcomes Through Investigations of Wabanaki Food Systems in Maine
May 01, 2026
Conditions: Food InsecurityInterventions: Behavioral: Upscaling the Wabanaki Mobile Food Pantry Program
Sponsors: Wabanaki Public Health and Wellness; Yale University; Washington State University
Not yet recruiting
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
May 01, 2026
Conditions: Heart Failure With Preserved Ejection Fraction (HFPEF); Coronary Artery DiseaseInterventions: Procedure: Percutaneous coronary intervention; Other: Placebo procedure
Sponsors: King's College London; Guy's and St Thomas' NHS Foundation Trust
Recruiting
Assessing Catecholamine Treatment Initiation Options: Norepinephrine vs Dopamine for Cardiogenic Shock
May 01, 2026
Conditions: Cardiogenic ShockInterventions: Drug: Norepinephrine; Drug: Dopamine Agent
Sponsors: Chonnam National University Hospital
Not yet recruiting
LBBAP vs. CS Pacing for CRT in Permanent Atrial Fibrillation and Heart Failure (SYNC-AF)
May 01, 2026
Conditions: Atrial Fibrillation (AF); Heart Failure; CardiomyopathiesInterventions: Device: Left Bundle Branch Area Pacing (LBBAP) for CRT; Device: Coronary Sinus (CS) Lead-Based Biventricular CRT
Sponsors: Yonsei University
Not yet recruiting
Effect of Beetroot Juice on Cardiovascular and Autonomic Responses to Exercise in Adults With Type 2 Diabetes
May 01, 2026
Conditions: Type 2 Diabetes Mellitus; Hypertension; Autonomic Nervous System DiseasesInterventions: Dietary Supplement: Beetroot juice; Dietary Supplement: Nitrate-depleted Beetroot Juice Placebo
Sponsors: Oxford Brookes University
Not yet recruiting
[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy
May 01, 2026
Conditions: Cardiac AmyloidosisInterventions: Drug: [64Cu]FBP8 PET/MR
Sponsors: Brigham and Women's Hospital
Recruiting
Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis
May 01, 2026
Conditions: Multiple Sclerosis; Depression - Major Depressive Disorder; FatigueInterventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsors: University of Calgary; Hotchkiss Brain Institute, University of Calgary
Not yet recruiting
Pilot Testing of Vagus Nerve Stimulation for Early Spinal Cord Injury Recovery
May 01, 2026
Conditions: Spinal Cord Injuries (Complete and Incomplete)Interventions: Device: Transauricular vagus nerve stimulation
Sponsors: University of Alabama at Birmingham
Not yet recruiting
Comparative Evaluation of Optrell and Octaray Mapping Catheters for Conduction Block Confirmation and Voltage Assessment During Atrial Ablation
May 01, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Device: Atrial Fibrillation Radiofrequency Ablation Only
Sponsors: Maxime Zabern
Not yet recruiting
Malaria CVD 36000; Gates INV090205
April 30, 2026
Conditions: Malaria (Plasmodium Falciparum)Interventions: Biological: PfSPZ Challenge (NF54); Device: Wearable Biosensor Devices; Other: Placebo
Sponsors: University of Maryland, Baltimore; Bill and Melinda Gates Foundation; Sanaria Inc.; University of Texas at Austin
Not yet recruiting
A Scalable Trans Diagnostic Intervention Targeting Adolescent Agency Supported by Conversational AI (AGENCIA)
April 30, 2026
Conditions: Irritability; Neurodevelopmental Disorders; Impulsivity; Emotional Dysregulation; Distress, Emotional; Distress, PsychologicalInterventions: Behavioral: AGENCIA Digital Self-Guided; Behavioral: AGENCIA In-person With Digital Assistant
Sponsors: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla; Hospitales Universitarios Virgen del Rocío; Instituto de Salud Carlos III
Not yet recruiting
High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients
April 30, 2026
Conditions: Tracheostomized Patients; Mechanical Ventilation Weaning; High Flow Oxygen TherapyInterventions: Device: High-flow tracheal oxygen (HFTO); Device: Tracheal Mask (TM)
Sponsors: King Faisal Specialist Hospital & Research Center
Not yet recruiting
Ventriloscope Simulation Stethoscope Training in PT and AT Students (VENTAS)
April 30, 2026
Conditions: Auscultation Training; Health Professions EducationInterventions: Behavioral: Traditional Auscultation Training; Behavioral: Ventriloscope Simulation Training
Sponsors: Youngstown State University
Not yet recruiting
DigitHeart Echo Study
April 30, 2026
Conditions: Heart Disease; Electrocardiograph; EchocardiographyInterventions: Diagnostic Test: echocardiography
Sponsors: The University of Hong Kong
Recruiting
SH-SDU Shandong Endometriosis Reproductive Cohort
April 30, 2026
Conditions: Endometriosis; Omics; Assisted Reproductive TechnologySponsors: The Second Hospital of Shandong University
Active, not recruiting
Evaluation of Chiglitazar Sodium With Lifestyle Intervention for Reversing Prediabetes
April 30, 2026
Conditions: PrediabetesInterventions: Drug: Chiglitazar sodium; Drug: Placebo
Sponsors: Second Xiangya Hospital of Central South University
Not yet recruiting
OCD LIFU Target Engagement
April 30, 2026
Conditions: Obsessive Compulsive Disorder (OCD)Interventions: Device: Low Intensity Focused Ultrasound
Sponsors: University of Pennsylvania; Attune Neurosciences Inc
Recruiting
Safety and Preliminary Activity of BI115 in Advanced SCLC
April 30, 2026
Conditions: Small Cell Lung Cancer (SCLC)Interventions: Drug: IBI115
Sponsors: Innovent Biologics (Suzhou) Co. Ltd.
Not yet recruiting
Effects of Emotional Freedom Technique and Music Therapy in High-Risk Pregnancy
April 30, 2026
Conditions: Preterm Premature Rupture of Membranes (PPROM); Premature Rupture of Membranes (PROM); High-Risk PregnancyInterventions: Behavioral: Emotional Freedom Technique (EFT); Behavioral: Music Therapy
Sponsors: Selcuk University
Not yet recruiting
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers
April 30, 2026
Conditions: Pharmacokinetics; Pharmacodynamics; Insulin AspartInterventions: Drug: I004; Drug: NovoLog
Sponsors: Amphastar Pharmaceuticals, Inc.
Recruiting
Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes
April 30, 2026
Conditions: Type 2 Diabetes; Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)Interventions: Drug: GLP-1 Receptor Agonists
Sponsors: The First Affiliated Hospital with Nanjing Medical University
Recruiting
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
April 30, 2026
Conditions: Non-communicable Diseases (NCD); Addiction to Opioids; Incarceration; Opioid-use DisordersSponsors: University of Thessaly; General Hospital of Trikala; General Hospital of Larissa; National Organization for the Prevention and Treatment of Addictions (EOPAE); 5th Regional Health Authority of Thessaly & Sterea; Correctional Facility (Prison) of Trikala; Region of Thessaly; University of Thessaly, Department of Nutrition and Dietetics
Recruiting
RDN for Heart Failure
April 30, 2026
Conditions: Heart FailureInterventions: Device: Renal denervation
Sponsors: Shanghai Golden Leaf MedTec Co. Ltd
Not yet recruiting
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
April 30, 2026
Conditions: Coronary Artery DiseaseSponsors: Emory University
Not yet recruiting
Supplementation With Salicornia Extract Rich in Polyphenols (B-Salicornia) to Improve Vascular Health in Patients With Dyslipidemia Who Are Not Candidates for Drug Treatment (Low to Moderate Risk)
April 30, 2026
Conditions: DyslipidemiaInterventions: Dietary Supplement: Halophyte plant extracts
Sponsors: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla; Joan Montaner Villalonga
Not yet recruiting
The Effects of Exercise Snacks on Endothelial Function and Body Composition in Overweight Individuals
April 30, 2026
Conditions: Overweight; ObesityInterventions: Behavioral: Short-term stair climbing exercise snack group; Behavioral: Long-duration stair climbing exercise snack group; Behavioral: Moderate-intensity continuous exercise（MICT）
Sponsors: Weifang Medical University
Not yet recruiting
Vexus Assessment and Natriuresis-guided Diuretic Therapy in Acute Heart Failure
April 30, 2026
Conditions: Venous Congestion; Heart Failure Acute; VExUS; DiureticsInterventions: Other: Natriuresis-guided escalation of loop diuretics
Sponsors: University Hospital, Akershus; Ostfold Hospital Trust
Not yet recruiting
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
April 30, 2026
Conditions: Exocrine Pancreatic Insufficiency (EPI); Cystic Fibrosis (CF); Pancreatic Enzyme Abnormality; Pancreatic DiseasesInterventions: Drug: NHS7108; Drug: Zenpep®
Sponsors: Aimmune Nestlé Health Science US R&D, LLC; Parexel
Not yet recruiting
Microvascular Dysfunction in Patients With Long-Covid Syndrome and Angina
April 30, 2026
Conditions: Long COVID; Angina (Stable); INOCA (Ischemia With Non Obstructive Coronary Artery Disease); Chronic Coronary SyndromeInterventions: Diagnostic Test: Coronary functional test
Sponsors: Fundacion Investigacion Interhospitalaria Cardiovascular
Active, not recruiting
Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals
April 29, 2026
Conditions: Sound Exposure; Exercise PerformanceInterventions: Behavioral: High-Level Headphone Sound Exposure; Behavioral: No-Sound Headphone Condition
Sponsors: Saglik Bilimleri Universitesi
Not yet recruiting
Patient Quality of Recovery After TAVR With Different Sedation Regimens
April 29, 2026
Conditions: Transcatheter Aortic Valve Replacement (TAVR); Aortic Valve StenosisInterventions: Drug: Propofol; Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl
Sponsors: David Lyubashevsky
Recruiting
Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US
April 29, 2026
Conditions: Obstructive Hypertrophic Cardiomyopathy (oHCM)Interventions: Drug: Mavacamten
Sponsors: Bristol-Myers Squibb
Recruiting
MedlyPeds Feasibility Study
April 29, 2026
Conditions: Pediatric Heart Failure; Congenital Heart Disease (CHD); Acquired Heart Disease; Pulmonary Hypertension; Post Cardiac SurgeryInterventions: Device: MedlyPeds App
Sponsors: The Hospital for Sick Children; University Health Network, Toronto
Not yet recruiting
Empagliflozin and CPAP in Adults With Heart Failure and Obstructive Sleep Apnea.
April 29, 2026
Conditions: Obstructive Sleep Apnea (OSA); Sleep Apnea Syndrome, Obstructive; Heart FailureInterventions: Drug: Empagliflozin; Device: Continuous Positive Airway Pressure (CPAP)
Sponsors: Medical University of Bialystok
Completed
Videolaryngoscope vs VideoLMA for Endotracheal Intubation in RIRS
April 29, 2026
Conditions: Urolithiasis; Airway ManagementInterventions: Device: Videolaryngoscope; Device: VideoLMA
Sponsors: Ela Erdem Hıdiroglu
Not yet recruiting
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
April 29, 2026
Conditions: Multiple MyelomaInterventions: Drug: Cevostamab; Drug: Pomalidomide; Drug: Dexamethasone; Drug: Daratumumab; Drug: Elotuzumab; Drug: Carfilzomib
Sponsors: Hoffmann-La Roche
Not yet recruiting
Effective of Early Treatment of Insomnia on the Adherence of CPAP
April 29, 2026
Conditions: Obstructive Sleep Apnea (OSA); Insomnia ChronicInterventions: Behavioral: digital CBT-I; Device: CPAP
Sponsors: Centre Hospitalier Universitaire Vaudois
Not yet recruiting
Role of Endothelial Progenitor Cells Dysregulation and Inflammation in the Pathophysiology of Cardiovascular Complications of Type 2 Diabetes
April 29, 2026
Conditions: Diabete Type 2; Cardio Vascular DiseaseSponsors: Weill Cornell Medical College in Qatar; Hamad Medical Corporation
Recruiting
Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients
April 29, 2026
Conditions: Hypertension; Hemodynamic Response; AnesthesiaInterventions: Drug: Dexmedetomidine; Other: Normal Saline
Sponsors: Sindh Institute of Urology and Transplantation
Completed
Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients.
April 29, 2026
Conditions: Reperfusion Injury; Post Cardiac Arrest Brain InjuryInterventions: Device: LUTICIA - Light Utilization COX-Inhibitory Device)
Sponsors: Mitovation, Inc; National Institutes of Health (NIH); National Institute of Neurological Disorders and Stroke (NINDS)
Not yet recruiting
Dexmedetomidine and Propofol for Sedation in Cataract Surgery.
April 29, 2026
Conditions: Sedation; Cataract; Hemodynamic; Hemodynamic Changes; Dexmedetomidine; Propofol Dosage; Fentanyl; Bradycardia; Tachycardia; Nausea and VomitingInterventions: Drug: Dexmedetomidine (DEX); Drug: Propofol (PRO); Drug: Fentanyl (FEN)
Sponsors: Saint-Joseph University
Recruiting
RELIEVE METAB Study
April 29, 2026
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)Interventions: Other: cardiac MRI; Other: Functional Testing
Sponsors: Heinrich-Heine University, Duesseldorf
Not yet recruiting
Effect of Chocolate Consumption Prior to Prolonged Sitting on Cardiovascular Health in Adults
April 29, 2026
Conditions: Cardiovascular Health During Prolonged SittingInterventions: Dietary Supplement: dark chocolate; Dietary Supplement: Milk Chocolate; Dietary Supplement: White Chocolate
Sponsors: King Saud University
Recruiting
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
April 29, 2026
Conditions: Transthyretin Amyloid Cardiomyopathy (ATTR-CM)Interventions: Device: Luscii
Sponsors: Bayer
Not yet recruiting
Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease
April 29, 2026
Conditions: PARKINSON DISEASE (Disorder)Interventions: Device: transcutaneous auricular vagus nerve stimulation
Sponsors: University of Alabama at Birmingham
Recruiting
XVIVO Heart Transplant Study in Clinical Practice
April 29, 2026
Conditions: Heart FailureInterventions: Device: XVIVO Heart Assist Transport System
Sponsors: XVIVO Perfusion
Recruiting
Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL
April 28, 2026
Conditions: Rheumatoid Arthritis; Major Adverse Cardiac EventsInterventions: Drug: Tofacitinib 5 MG
Sponsors: Shaikh Zayed Hospital, Lahore
Recruiting
High-intensity Walking Rehabilitation in Outpatient Subacute Spinal Cord Injury
April 28, 2026
Conditions: Spinal Cord Injuries (SCI)Interventions: Behavioral: High-intensity Rehabilitation; Behavioral: Usual Care
Sponsors: University of Alberta; Alberta Paraplegic foundation
Not yet recruiting
Auricular Acupuncture Therapy Administered by Village Doctors Improves Sleep Quality in Elderly Patients With Comorbid Diabetes Mellitus and Hypertension
April 28, 2026
Conditions: Cardiometabolic Diseases; Insomnia DisorderInterventions: Device: Auricular Acupuncture Therapy; Device: Sham Auricular Acupuncture Group
Sponsors: Jiangsu Taizhou People's Hospital
Not yet recruiting
Tele-exercise Training Program for Long COVID
April 28, 2026
Conditions: Long COVIDInterventions: Device: Telehealth exercise training program; Behavioral: Education and self-exercise
Sponsors: Tri-Service General Hospital
Completed
Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers
April 28, 2026
Conditions: Lung CarcinomaInterventions: Procedure: Accelerometry; Other: Aerobic Exercise; Procedure: Biospecimen Collection; Other: Educational Intervention; Other: Electronic Health Record Review; Other: Physical Performance Testing; Procedure: Respiratory Muscle Training; Other: Supportive Care; Other: Survey Administration
Sponsors: Roswell Park Cancer Institute
Not yet recruiting
A Multimodal Prospective Cohort Study of Parkinsonism
April 28, 2026
Conditions: Parkinsonism; REM Sleep Behavior DisorderSponsors: Ruijin Hospital
Recruiting
Comparison of Single-syringe vs. Double-syringe Techniques for Adenosine Administration in PSVT
April 28, 2026
Conditions: Supraventricular Tachycardia; Supraventricular Tachycardias; Supraventricular Arrhythmia; SVT; PSVTInterventions: Drug: Single-syringe Adenosine; Drug: Double Syringe Adenosine
Sponsors: Hormozgan University of Medical Sciences
Completed
Dance Intervention in Breast Cancer Treatment
April 28, 2026
Conditions: Breast Cancer; Breast - Female; Breast Cancer FemalesInterventions: Behavioral: Dance Program Group
Sponsors: Federal University of Maranhao
Active, not recruiting
4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis
April 28, 2026
Conditions: Cirrhosis; Portal HypertensionInterventions: Other: 4D-Flow Liver and heart MRI with Gadolinium injection; Biological: Samples Without DNA
Sponsors: Assistance Publique - Hôpitaux de Paris; Sorbonne University; Institute of Cardiometabolism and Nutrition, France
Not yet recruiting
An Observational Study, Called FINEXPLORER, to Learn More About How Well Finerenone Works in Adults in Spain With Chronic Kidney Disease (CKD) Linked to Type 2 Diabetes, by Looking at Changes in a CKD Risk Score
April 28, 2026
Conditions: Chronic Kidney Disease; Type 2 Diabetes MellitusInterventions: Drug: Finerenone (Kerendia, BAY94-8862)
Sponsors: Bayer
Not yet recruiting