ClinicalTrials.gov: Other terms: heart disease | First posted in the last 14 days
Studies found on ClinicalTrials.gov by a search of: Other terms: heart disease | First posted in the last 14 days
Erector Spinae Oxygen Saturation and AKI After OPCAB
August 12, 2026
Conditions: Acute Kidney Injury; Coronary Artery Disease; Coronary Artery Bypass, Off-Pump; Postoperative Complications; Cardiac Surgical Procedures; Spectroscopy, Near-InfraredInterventions: Device: Near-infrared spectroscopy monitoring of erector spinae muscle and renal regional oxygen saturation
Sponsors: Yonsei University
Not yet recruiting
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
August 12, 2026
Conditions: Healthy Aging; Inflammaging; Metabolic Health; Quercetin; Coenzyme Q10Interventions: Dietary Supplement: Quercetin (dietary supplement); Dietary Supplement: Coenzyme Q10; Dietary Supplement: Rice Flour
Sponsors: Applied Science & Performance Institute
Not yet recruiting
Prophylactic IABP in Delayed-Presentation Anterior STEMI
August 12, 2026
Conditions: Acute Anterior ST-Segment Elevation Myocardial InfarctionInterventions: Device: Intra-Aortic Balloon Pump; Procedure: Primary Percutaneous Coronary Intervention
Sponsors: Qilu Hospital of Shandong University
Not yet recruiting
Screen-delivered Augmented-reality Preparation and Anxiety Before Pediatric Adenotonsillectomy in China
August 12, 2026
Conditions: Tonsillectomy; Preoperative Care; AnxietyInterventions: Other: Screen-delivered augmented-reality group; Other: Usual Care Group
Sponsors: Central South University
Completed
Using Non-Invasive Mapping To Eliminate Structural Heart Disease Ventricular Tachycardia
August 12, 2026
Conditions: Ventricular Tachycardia (VT); Catheter AblationInterventions: Device: VIVO-assisted mapping
Sponsors: University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust
Recruiting
Intraoperative Dexmedetomidine Use and Postoperative Delirium After Cardiac Surgery
August 12, 2026
Conditions: Postoperative DeliriumInterventions: Drug: Dexmedetomidine
Sponsors: Shusheng Li
Completed
Effects of Exercise Snacks on Physical Health and Cognitive Function in Individuals With Intellectual Disabilities
August 12, 2026
Conditions: Intellectual DisabilityInterventions: Behavioral: High-Intensity Interval Training; Behavioral: Exercise Snacks
Sponsors: University of Macau
Not yet recruiting
Turkish Chronic Total Occlusion Percutaneous Coronary Intervention Registry
August 12, 2026
Conditions: Chronic Total Occlusion (CTO); Coronary Artery DiseaseSponsors: Ahmet Seyfeddin Gürbüz
Not yet recruiting
Combination Therapy of Deferiprone and N-Acetylcysteine for Treating Negative Symptoms in Schizophrenia
August 12, 2026
Conditions: Schizoaffecitve Disorder; Schizophrenia and Schizoaffective Disorder; Schizophrenia and Predominant Negative SymptomsInterventions: Drug: Deferiprone (DFP); Drug: N-Acetyl Cysteine (NAC)
Sponsors: Amit Lotan; Hadassah Medical Organization; Jerusalem Mental Health Center; Hebrew University of Jerusalem
Not yet recruiting
Food As Medicine to Reduce CKD Burden in Health Disparity Populations
August 12, 2026
Conditions: Chronic Kidney DiseaseInterventions: Behavioral: Culinary Medicine Nutrition and Cooking Education
Sponsors: University of Texas Southwestern Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Not yet recruiting
Phenotyping Acute Non-Severe Anemia in the Emergency Department
August 12, 2026
Conditions: AnemiaInterventions: Device: Total hemoglobin mass measurement; Diagnostic Test: Focused transthoracic echocardiography; Diagnostic Test: Near-infrared spectroscopy; Other: Blood rheology assessment; Other: Symptom assessment
Sponsors: Hospices Civils de Lyon
Not yet recruiting
The Influence of Plan B® on Cardiovascular Health.
August 12, 2026
Conditions: Female; PremenopausalInterventions: Drug: Plan B (Levonorgestrel); Other: Placebo (gelatin capsule)
Sponsors: McMaster University
Recruiting
A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag
August 12, 2026
Conditions: Pulmonary Arterial Hypertension (PAH)Interventions: Combination Product: LIQ861 (treprostinil) inhalation powder
Sponsors: Liquidia Technologies, Inc.
Not yet recruiting
Non-Wearable Audiovisual Distraction for Children's Medical Anxiety in the ED
August 12, 2026
Conditions: Pediatric AnxietyInterventions: Behavioral: Non-Wearable Audiovisual Distraction; Other: Routine ED Care
Sponsors: National Taiwan University Hospital; National Yunlin University of Science and Technology
Not yet recruiting
Tricuspid Valve Reconstruction Using the Right Atrial Appendage
August 12, 2026
Conditions: Tricuspid Valve DiseaseInterventions: Procedure: Tricuspid Valve Reconstruction; Procedure: tricuspid valve replacement
Sponsors: Zagazig University
Enrolling by invitation
Polygonatum Sibiricum Reduces Visceral Fat in Obese Adults
August 12, 2026
Conditions: Visceral Obesity; Metabolic SyndromeInterventions: Dietary Supplement: Polygonatum sibiricum; Behavioral: Lifestyle Intervention
Sponsors: Zhejiang Provincial Tongde Hospital
Not yet recruiting
Physiological Changes in Adult Intensive Care Patients Following Contact With Their Primary Caregiver
August 12, 2026
Conditions: Critical Illness; Critically Ill PatientsInterventions: Other: Standardized therapeutic physical contact
Sponsors: Universidad Autonoma del Estado de Mexico
Recruiting
Bundle Branch Pacing to Preserve Ejection Fraction in Atrial Fibrillation Trial
August 12, 2026
Conditions: Permanent Atrial Fibrillation; Preserved Ejection FractionInterventions: Procedure: LBBA pacing; Procedure: Conventional pacing
Sponsors: Poitiers University Hospital; University Hospital, Grenoble; Nouvelles Cliniques Nantaises, Nantes; Centre Hospitalier Universitaire de Besancon; Centre Hospitalier de PAU; Centre Cardiologique du Nord, St Denis; Centre Hospitalier Universitaire de Saint Etienne; LA ROCHE SUR YON HOSPITAL; Centre Hospitalier Régional d'Orléans; University Hospital, Tours
Not yet recruiting
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
August 12, 2026
Conditions: Generalized Anxiety DisorderInterventions: Drug: SEP-363856; Other: Placebo
Sponsors: Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting
Er:YAG Laser Versus Conventional Cavity Preparation in Children With Molar-Incisor Hypomineralization
August 12, 2026
Conditions: Molar-Incisor Hypomineralization (MIH)Interventions: Device: Er:YAG Laser-Assisted Cavity Preparation; Procedure: Conventional Rotary Cavity Preparation
Sponsors: Ege University
Active, not recruiting
Tirofiban Combined With Aspirin in Moderate Ischemic Stroke
August 12, 2026
Conditions: Ischemic Stroke, AcuteInterventions: Drug: Tirofiban; Drug: Tirofiban-matching placebo
Sponsors: Xinqiao Hospital of Chongqing; The First Affiliated Hospital of Nanchang University
Not yet recruiting
Oliceridine-Propofol Dose for Gastroscope Insertion in Obese Patients
August 12, 2026
Conditions: Obesity; Gastrointestinal EndoscopyInterventions: Drug: Low-Dose Oliceridine Group; Drug: High-Dose Oliceridine Group
Sponsors: Lu Yi
Not yet recruiting
Prevalence, Severity of Dysmenorrhea and Effectiveness of Structured Physiotherapy Interventions Among Doctor of Physical Therapy Students: A Randomized Controlled Trial
August 12, 2026
Conditions: Primary Dysmenorrhea (PD)Interventions: Behavioral: Structured Physiotherapy Program; Other: Conventional Treatment for Primary Dysmenorrhea
Sponsors: Muhammad Nawaz Sharif University of Agriculture Multan
Completed
Effect of Extra Virgin Olive Oil Consumption on the Occurrence of Cardiovascular Events in Population Living With HIV
August 12, 2026
Conditions: HIV - Human Immunodeficiency VirusInterventions: Dietary Supplement: The patients must ingest 50 mL of extra virgin olive oil daily
Sponsors: Fundacion SEIMC-GESIDA
Not yet recruiting
Transcutaneous Auricular Vagus Nerve Stimulation for Recovery of Consciousness After Surgery for Spontaneous Intracerebral Hemorrhage
August 12, 2026
Conditions: Disorders of Consciousness; Spontaneous Intracerebral HemorrhageInterventions: Device: Active Transcutaneous Auricular Vagus Nerve Stimulation; Device: Sham Transcutaneous Auricular Vagus Nerve Stimulation
Sponsors: Beijing Tiantan Hospital; Beijing Friendship Hospital; First Affiliated Hospital of Fujian Medical University; Liaocheng People's Hospital
Recruiting
Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study
August 12, 2026
Conditions: Cardiac Arrest (CA); Intensive Care Unit (ICU) Admission; Return of Spontaneous Circulation; ComatoseInterventions: Other: Value of neurofilament light chain (NFL) at different time points
Sponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting
Calisthenics Versus Cycling Exercises on Interleukin-6 and Quality of Life in Benha University Students With Irritable Bowel Syndrome
August 12, 2026
Conditions: Irritable Bowel SyndromeInterventions: Other: Calisthenics exercises; Other: Cycling Exercises; Other: diet advices
Sponsors: Cairo University
Not yet recruiting
A Clinical Investigational Study of Ankura™ II AAA, IE and AE Stent Graft System for Endovascular Treatment of Abdominal Aortic Aneurysm
August 12, 2026
Conditions: Abdominal Aortic Aneurysms (AAA)Interventions: Device: Ankura™ II Abdominal Aortic Stent Graft System
Sponsors: Lifetech Scientific (Shenzhen) Co., Ltd.
Not yet recruiting
Evaluation of Fetal Heart
August 12, 2026
Conditions: Fetal Growth RestrictionInterventions: Procedure: Echocardiography
Sponsors: Assiut University
Not yet recruiting
Cardiorespiratory Assessment Prior to Scoliosis Surgery: a 10-year Experience at a Specialized Scoliosis Center
August 12, 2026
Conditions: Scoliosis; Restrictive Pulmonary Disease; Pulmonary Hypertension; Restrictive Breathing PatternInterventions: Procedure: respiratory function test
Sponsors: Poitiers University Hospital
Active, not recruiting
Endotracheal Tube Intolerance and Respiratory Airflow Perception
August 12, 2026
Conditions: Coughing Responses at Tracheal Extubation; Breathing PatternsSponsors: Peking University People's Hospital
Not yet recruiting
Assessing the Feasibility of the "Heart Care Pairs" Intervention
August 12, 2026
Conditions: Hypertension (HTN)Interventions: Behavioral: Dyadic lifestyle intervention for CVD risk reduction
Sponsors: University of Alabama at Birmingham; National Institute on Minority Health and Health Disparities (NIMHD)
Not yet recruiting
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
August 12, 2026
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF); Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)Interventions: Drug: Elecoglipron; Drug: Placebo
Sponsors: AstraZeneca
Not yet recruiting
Parasternal Intercostal Plane Catheter for Pain Control After CABG Surgery
August 12, 2026
Conditions: Bypass Surgery; Arrythmia; Postoperative PainInterventions: Other: Parasternal blocks
Sponsors: Koc University Hospital
Not yet recruiting
Pedal Pump Clinical Trial on Edema V1
August 12, 2026
Conditions: Lower Extremity Edema; Congestive Heart Failure(CHF); Chronic Venous Insufficiency (CVI); Kidney DiseaseInterventions: Device: Pedal Pump; Device: Pedal Pump Sham
Sponsors: David McVay
Recruiting
A Feasibility Study of the Improving Health and Lifestyle Programme After Stroke (iHeLP)
August 12, 2026
Conditions: StrokeInterventions: Behavioral: The Improving Health and Lifestyle Programme (iHeLP)
Sponsors: University of Limerick; Health Research Board, Ireland
Completed
The FLARE (Flurpiridaz vs. Rubidium Evaluation) Trial
August 12, 2026
Conditions: Coronary Artery Disease; Coronary Microvascular DiseaseSponsors: University of California, Los Angeles; VA Greater Los Angeles Healthcare System
Recruiting
The Effect of Hydration on the Prevention of CI-AKI in STEMI Patients Undergoing Primary PCI (Hydro-AKI Trial)
August 12, 2026
Conditions: Contrast-Induced Acute Kidney Injury in ST-Segment Elevation Myocardial InfarctionInterventions: Other: oral hydration protocol
Sponsors: Assiut University
Not yet recruiting
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
August 12, 2026
Conditions: Non Small Cell Lung Cancer; Cardiotoxicity; Locally Advanced Non-Small Cell Lung Cancer; Radiation TherapyInterventions: Diagnostic Test: PET/CT 18F-Flurpiridaz Rest/Stress Test; Device: Coronary CT Angiography (CCTA); Drug: 18F-Flurpiridaz
Sponsors: Indiana University
Recruiting
CS1 Added to Standard of Care Therapy for Pulmonary Arterial Hypertension
August 12, 2026
Conditions: Pulmonary Arterial HypertensionInterventions: Drug: CS1; Drug: Placebo
Sponsors: Cereno Scientific AB
Not yet recruiting
Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP)
August 12, 2026
Conditions: Respiratory Recurrent Papillomatosis (RRP); Human Papillomavirus (HPV); Papillomavirus Infection; Laryngeal Diseases; Tracheal Diseases; Respiratory Tract NeoplasmInterventions: Drug: PRGN-2012; Drug: Bevacizumab
Sponsors: National Cancer Institute (NCI)
Not yet recruiting
Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort
August 11, 2026
Conditions: Depression - Major Depressive Disorder; Adjustment Disorder; Burnout SyndromeSponsors: Clinica Holistica Engiadina; University Basel, Department of Sport, Exercise and Health, Division of Sport Science and Psychosocial Health
Recruiting
Peripheral Blood Lipidomic and Ceramide Profiles in Atrial Fibrillation
August 11, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Other: Peripheral blood untargeted lipidomic profiling; Other: Peripheral blood targeted ceramide assay
Sponsors: First Affiliated Hospital Xi'an Jiaotong University
Recruiting
A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (DE)
August 11, 2026
Conditions: Mitral Valve (MV) RegurgitationInterventions: Device: Transcatheter mitral valve repair (MRace Implant and Delivery System)
Sponsors: Polares Medical SA
Not yet recruiting
Safety Assessment of H2 Inhalation in Patients With Mild Cognitive Impairment
August 11, 2026
Conditions: Mild Cognitive Impairment (MCI)Interventions: Combination Product: Molecular hydrogen inhalation
Sponsors: University of Ostrava; Cerebrovaskularni poradna s.r.o.
Recruiting
Brain-Heart Axis in Type 2 Diabetes Mellitus
August 11, 2026
Conditions: Type 2 Diabetes Mellitus (T2DM)Sponsors: Hacettepe University
Recruiting
Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia
August 11, 2026
Conditions: Sarcopenia; Nerve BlockInterventions: Other: sarcopenia; Other: Non-sarcopenia; Procedure: General Anesthesia; Procedure: Nerve Block
Sponsors: Chang Gung Memorial Hospital
Not yet recruiting
Epigenetic Changes in Long COVID Patients
August 11, 2026
Conditions: Long COVID-19 Syndrome; Long COVID SymptomsSponsors: Istituti Clinici Scientifici Maugeri SpA; IRCCS Ospedale San Raffaele; Istituto Auxologico Italiano
Not yet recruiting
A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU)
August 11, 2026
Conditions: Mitral Valve (MV) RegurgitationInterventions: Device: Transcatheter mitral valve repair
Sponsors: Polares Medical SA
Not yet recruiting
Intergenerational Risk and Resilience of Rohingya in Displacement
August 11, 2026
Conditions: Child Development; Early Child Development; Mental Health; PTSD - Post Traumatic Stress Disorder; Intergenerational Trauma; Refugee HealthSponsors: New York University; International Centre for Diarrhoeal Disease Research, Bangladesh; The LEGO Foundation; University of California, Davis
Active, not recruiting
The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms
August 11, 2026
Conditions: Posttraumatic Stress Disorder (PTSD); Substance Use Disorder (SUD)Interventions: Behavioral: Trauma Informed Heart Rate Variability Biofeedback; Behavioral: Present Centered Therapy
Sponsors: Coatesville VA Medical Center
Recruiting
Achieving Optimal Medical Therapy Through Percutaneous Treatment of Secondary Mitral Regurgitation to Improve Outcome in Patients With HFrEF
August 11, 2026
Conditions: Mitral Regurgitation Functional; Heart Failure With Reduced Ejection Fraction (HFrEF)Interventions: Device: M-TEER; Other: Standardized GDMT Up-Titration
Sponsors: University Medical Center Mainz; Abbott
Not yet recruiting
Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma
August 11, 2026
Conditions: Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic LymphomaInterventions: Biological: Autologous BAFFR-targeting CAR T Cells; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Procedure: Bridge Therapy; Procedure: Chest Radiography; Procedure: Computed Tomography; Drug: Cyclophosphamide; Procedure: Echocardiography Test; Drug: Fludarabine; Procedure: Leukapheresis; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography; Procedure: Ultrasonographic Elastography
Sponsors: City of Hope Medical Center; National Cancer Institute (NCI)
Not yet recruiting
A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (FR)
August 11, 2026
Conditions: Mitral Valve (MV) RegurgitationInterventions: Device: Transcatheter mitral valve repair (MRace Implant and Delivery System)
Sponsors: Polares Medical SA
Not yet recruiting
CAPITAL OFFLOAD-SHOCK
August 11, 2026
Conditions: Hypervolemia; Cardiogenic Shock; Renal Replacement TherapyInterventions: Drug: Immediate renal replacement therapy
Sponsors: Ottawa Heart Institute Research Corporation
Not yet recruiting
The Use of Artificial Intelligence-Enhanced Electrocardiograms in the Chest Pain Clinic to Risk Stratify Patients, Provide Rapid Reassurance and Enable a Low-Cost Clinical Pathway
August 11, 2026
Conditions: Angina (Stable); Chest Pain Atypical SyndromeInterventions: Diagnostic Test: AI-ECG
Sponsors: Jamil Mayet; Imperial College Healthcare NHS Trust
Not yet recruiting
Comparison of Sedated and Unsedated PEG in Elderly ASA IV Patients
August 11, 2026
Conditions: Percutaneous Endoscopic Gastrostomy; Enteral Nutrition Feeding; Dysphagia; Elderly Patients (>65 Years); ASA Physical Status IVSponsors: Mersin University
Not yet recruiting
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
August 11, 2026
Conditions: SchizophreniaInterventions: Drug: LTX-001 once daily; Drug: Placebo; Drug: LTX-001 twice daily
Sponsors: Leal Therapeutics, Inc
Recruiting
Pneumonia After Cardiovascular Surgery With Artificial Intelligence
August 11, 2026
Conditions: Hospital Acquired PneumoniaInterventions: Other: Not applicable- observational study
Sponsors: Tomsk National Research Medical Center of the Russian Academy of Sciences; National Research Tomsk State University; Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Recruiting
Multimodal Biomarkers and Precision TMS for Postpartum Depression
August 11, 2026
Conditions: Depression, PostpartumInterventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS)
Sponsors: University of Macau; Kiang Wu Hospital
Not yet recruiting
Comprehensive Clinical Prediction Rule for Acute Heart Failure
August 11, 2026
Conditions: Acute Heart Failure (AHF)Interventions: Diagnostic Test: Acute Heart Failure Diagnostic Method
Sponsors: Chinese University of Hong Kong; Prince of Wales Hospital, Shatin, Hong Kong; The University of Hong Kong; Tuen Mun Hospital, Hospital Authority, Hong Koong; Queen Mary Hospital, Hong Kong
Not yet recruiting
Effect of Tranexamic Acid on Bleeding After Bariatric Surgery
August 10, 2026
Conditions: Morbid Obesity; Perioperative Hemorrhage; Obesity; Tranexamic Acid; Postoperative HemorrhageSponsors: G.Gennimatas General Hospital
Completed
The BASIC-S Feasibility Study for Vascular Risk Reduction
August 10, 2026
Conditions: Hypertension (HTN); Vascular Diseases; Stroke; Dementia; Cardiovascular Risk Factor; Cognitive DeclineInterventions: Behavioral: BASIC-S Intervention; Behavioral: Standard / Usual Care
Sponsors: Andrew Appleton; Academic Medical Organization of Southwestern Ontario
Not yet recruiting
Adapted Cardiopulmonary Resuscitation Study
August 10, 2026
Conditions: Cardiac Arrest (CA)Interventions: Procedure: aCPR algorithm; Procedure: ERC ALS 2025
Sponsors: Johannes Kepler University of Linz; Red Cross Upper Austria; Kepler University Hospital
Recruiting
Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE)
August 10, 2026
Conditions: Valvular Heart Disease Patients; Aortic Stenosis; Mitral Regurgitation; Left Ventricular Diastolic DysfunctionInterventions: Device: Kosmos Torso-One AI-guided Point-of-Care Ultrasound (EchoNous, Inc.)
Sponsors: University of Texas Southwestern Medical Center
Not yet recruiting
Bioequivalence Study of ADC118 Tablets in Healthy Chinese Volunteers Under Fasting Conditions
August 10, 2026
Conditions: Human Immunodeficiency Virus (HIV) InfectionInterventions: Drug: ACC118-Test; Drug: Reference
Sponsors: Jiangsu Aidea Pharmaceutical Group Co., Ltd.
Completed
Qing-Xin-Jiao-Tai Decoction for Insomnia Comorbid With Obesity Presenting With Heart-Kidney Non-interaction Syndrome
August 10, 2026
Conditions: Insomnia; ObesityInterventions: Drug: Qingxin Jiaotai Decoction; Drug: Placebo
Sponsors: Fohow Pharmaceutical Group; Xiyuan Hospital of China Academy of Chinese Medical Sciences
Not yet recruiting
Circulating Tumor Extracellular Vesicles for Non-Invasive Monitoring of Metastatic Colorectal Cancer
August 10, 2026
Conditions: Metastatic Colorectal CancerInterventions: Other: Blood sample
Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not yet recruiting
Transcranial Temporal Interference Stimulation (tTIS) for Chronic Insomnia
August 10, 2026
Conditions: Chronic InsomniaInterventions: Device: Active Transcranial Temporal Interference Stimulation (tTIS)-Experimental; Device: Sham Transcranial Temporal Interference Stimulation (tTIS)-Sham Comparator
Sponsors: Ruijin Hospital
Not yet recruiting
Wand STA vs SleeperOne for Pediatric Local Anesthesia (WASO-Kids)
August 10, 2026
Conditions: Dental Anxiety; Pain ManagementInterventions: Device: Computer-controlled local anesthetic delivery system (pressure-sensing, single-tooth anesthesia type); Device: Computer-controlled local anesthetic delivery system (corded, pen-style electronic type)
Sponsors: National and Kapodistrian University of Athens
Completed
Clinical Trial of the Safety and Tolerability of MMH-522 in Healthy Volunteers
August 10, 2026
Conditions: CoughInterventions: Drug: MMH-522
Sponsors: Materia Medica Holding
Completed
Predictors of Sleep Quality in Patients Undergoing Open-Heart Surgery
August 10, 2026
Conditions: Sleep Quality; Intensive Care (ICU); Nursing CareSponsors: Aydin Adnan Menderes University
Completed
Comparison of Dynamic Compliance and Airway Resistance in Pressure-Controlled Versus Volume-Controlled Ventilation in Children Undergoing Corrective Heart Surgery
August 10, 2026
Conditions: Atrial Septal Defect; Ventricular Septal Defects; Pulmonary Hypertension; Intracardiac and Septal DefectsInterventions: Other: Pressure Controlled Ventilation; Other: Volume Controlled Ventilation
Sponsors: Nilratan Sircar Medical College
Completed
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
August 10, 2026
Conditions: Type 2 DiabetesInterventions: Drug: Placebo; Drug: Survodutide
Sponsors: Boehringer Ingelheim
Not yet recruiting
The Effect of Ligament of Marshall Excision During Minimally Invasive Cardiac Surgery-Coronary Artery Bypass Grafting (MICS-CABG) on the Prevention of Postoperative New-Onset Atrial Fibrillation: A Multicenter, Prospective, Randomized, Triple-Blinded Study
August 10, 2026
Conditions: Postoperative Atrial FibrillationInterventions: Procedure: MICS-CABG combined with excision of the Ligament of Marshall
Sponsors: Peking University Third Hospital
Not yet recruiting
The NEU - CAP Trial
August 10, 2026
Conditions: Infant, Premature, Diseases; Birth, Preterm; Respiratory Distress NeonatalInterventions: Procedure: Local standard care of monitoring non-invasive ventilation; Procedure: CO₂-guided Non-Invasive Ventilation
Sponsors: Leiden University Medical Center
Not yet recruiting
Cuffless BP Monitoring in Hemodialysis
August 10, 2026
Conditions: ESRD on HDInterventions: Device: CART BP Pro
Sponsors: Gangnam Severance Hospital
Enrolling by invitation
Priming Using Contrast Training Exercise
August 10, 2026
Conditions: Athletic PerformanceInterventions: Behavioral: Morning Complex-Contrast Training; Behavioral: Time-Matched Walking Control Condition
Sponsors: The Jerzy Kukuczka Academy of Physical Education in Katowice
Completed
BHB-1893 Versus Metoprolol for Symptomatic Obstructive Hypertrophic Cardiomyopathy
August 10, 2026
Conditions: Cardiomyopathy, Hypertrophic ObstructiveInterventions: Drug: BHB-1893; Drug: Metoprolol
Sponsors: Braveheart Bio, Inc.
Not yet recruiting
Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain
August 10, 2026
Conditions: Peripheral Neuropathic PainInterventions: Drug: Gabapentin; Drug: Pregabalin
Sponsors: Giresun University
Not yet recruiting
PULSTA TPV Observational Study
August 10, 2026
Conditions: Heart DiseaseSponsors: Taewoong Medical Co., Ltd.; Avania
Not yet recruiting
Bioequivalence Study of Valsatril Tablet Versus Entresto® Sacubitril/Valsartan 24/26 mg Tablet.
August 10, 2026
Conditions: Healthy ParticipantsInterventions: Drug: Valsatril®; Drug: Entresto®
Sponsors: Center for Bioequivalence Studies and Clinical Research; SAMI Pharmaceuticals (Pvt.) Ltd.
Completed
Virtual Reality Exergaming During Work Breaks in Office Employees
August 10, 2026
Conditions: Exergaming; Virtual Reality Physical Activity; Workplace ExerciseInterventions: Behavioral: Gamified Virtual Reality Exergaming (GVRE); Behavioral: Serious Virtual Reality Exergaming (SVRE); Behavioral: Traditional Video Exercise (TVE)
Sponsors: Akdeniz University; The Scientific and Technological Research Council of Turkey
Recruiting
Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research
August 10, 2026
Conditions: Pericarditis; Tako-TSUBO Cardiomyopathy; Myocarditis; Inflammatory Cardiomyopathies; Lupus; Systemic Sclerosis; Antiphospholipid Syndrome; Idiopathic Inflammatory Myopathies; Rheumatoid Arthritis; Spondyloarthritis; ANCA-associated Vasculitis; Takayasu Arteritis; Giant Cell Arteritis; Behçet Disease; Still DiseaseSponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting
Net Clinical Benefit of Edoxaban Versus Apixaban in Patients With Atrial Fibrillation and Coronary Artery Disease
August 10, 2026
Conditions: Atrial Fibrillation (AF); Coronary Arterial Disease (CAD)Interventions: Drug: Edoxaban; Drug: Apixaban
Sponsors: Samsung Medical Center
Recruiting
Probiotic Research for Mental Health in Adult Volunteers
August 07, 2026
Conditions: Healthy Adult ParticipantsInterventions: Dietary Supplement: Probiotic; Dietary Supplement: Placebo
Sponsors: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Not yet recruiting
Association of Heart Failure Aggravation and Device-based Sensor Parameters
August 07, 2026
Conditions: Heart Failure; CardiomyopathyInterventions: Device: ICD/CRT-D equipped with HeartLogic, Sleep Incline, and Apnea Scan functions
Sponsors: Samsung Medical Center
Active, not recruiting
Breathing Exercises for Dyspnea and Anxiety in Heart Failure
August 07, 2026
Conditions: Heart Failure; Breathing Exercises; Dyspnea; AnxietyInterventions: Other: Diaphragmatic and Pursed-Lip Breathing Exercises
Sponsors: Istanbul University - Cerrahpasa
Active, not recruiting
A Study Of Subscalp Placement Of The LINQII Device
August 07, 2026
Conditions: Cranial NeurosurgeryInterventions: Device: Medtronic LINQII
Sponsors: Mayo Clinic
Enrolling by invitation
Prospective Multicenter Study Evaluating Myval TAVR Safety and Effectiveness in High-risk Severe AR
August 07, 2026
Conditions: Aortic Regurgitation; Aortic Disease; Calcified Aortic ValveInterventions: Device: Myval THV series
Sponsors: Ceric Sàrl
Not yet recruiting
Ezetimibe for Arrhythmia Recurrence After AF Ablation
August 07, 2026
Conditions: Atrial Fibrillation; Post-Catheter Ablation Atrial Arrhythmia RecurrenceInterventions: Drug: Ezetimibe; Other: Standardized post-ablation clinical management
Sponsors: Second Affiliated Hospital, Zhejiang University, School of Medicine
Not yet recruiting
Smartphone Based-PPG Assessment of REconversion in Persistent Atrial Fibrillation
August 07, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Device: Smartphone-based PPG monitoring
Sponsors: Ziekenhuis Oost-Limburg; Universitaire Ziekenhuizen KU Leuven
Not yet recruiting
Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System
August 07, 2026
Conditions: Cardiac Diseases; Sickle Cell Disease; Hypertension; Diabetes Mellitus; Heart Failure; Congenital Heart Disease; Rheumatic Heart Disease; Epilepsy; Cancer; Mental Health Disorders; Kidney DiseaseInterventions: Combination Product: Supportive treatment
Sponsors: Centre for Infectious Disease Research in Zambia; The Leona M. and Harry B. Helmsley Charitable Trust
Recruiting
Virtual Breathing Intervention for Enhancing Asthma-related Quality of Life - A Randomized Controlled Trial
August 07, 2026
Conditions: Asthma BronchialeInterventions: Behavioral: Virtual Breathing Training Program; Other: Usual Care Group
Sponsors: Prof. Dr. Andreas Rembert Koczulla; Cegla Medizintechnik GmbH
Not yet recruiting
Unilateral and Bilateral Resistance Training in Hypertension
August 07, 2026
Conditions: HypertensionInterventions: Other: Unilateral Resistance Training; Other: Bilateral Resistance Training
Sponsors: Hacettepe University
Recruiting
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
August 07, 2026
Conditions: Iron Deficiency Anemia; Coronary Artery Disease; Heart Failure With Preserved Ejection Fraction (HFPEF)Sponsors: Alcea
Not yet recruiting
Standard of Care Comparative Arm of Phase 1/2 Gene Therapy Trial DREPAMIR" in Severe Sickle Cell Disease Patients
August 07, 2026
Conditions: Sickle Cell Disease (SCD); Vaso-occlusive EventsInterventions: Drug: standard of care
Sponsors: Assistance Publique - Hôpitaux de Paris; URC-CIC Paris Descartes Necker Cochin; Imagine Institute; Association Française contre les Myopathies (AFM), Paris; Marie Lannelongue Hospital
Not yet recruiting
Durability of Pulmonary Vein Isolation With Farapulse System Using Minimal Fluoroscopy
August 07, 2026
Conditions: Atrial Fibrillation (AF); Pulsed-field AblationInterventions: Device: catheter ablation
Sponsors: Semmelweis University
Completed
The Impact of Intra-Abdominal Pressure on Mortality and Morbidity in Patients Undergoing Open-Heart Surgery
August 07, 2026
Conditions: Intra-Abdominal Hypertension; Postoperative ComplicationsSponsors: Bursa Yuksek Ihtisas Training and Research Hospital
Completed
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding
August 07, 2026
Conditions: Hemorrhage; Gastrointestinal Hemorrhage; Hemoptysis; Postpartum HemorrhageInterventions: Device: Embolization therapy
Sponsors: Aesculap AG
Not yet recruiting
Investigation on the Chronic Effects of Nepalese Pepper (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Action Video Gamers
August 07, 2026
Conditions: Cognition; Mood; Gaming Performance; FatigueInterventions: Dietary Supplement: Nepalese Pepper (Zanthoxylum Armatum DC) extract 275mg; Dietary Supplement: Placebo
Sponsors: Northumbria University; Solabia Biochemistry AG
Not yet recruiting
Modulatory Effects of Personalized Transcranial Magnetic Stimulation (TMS) on Heart-Brain Coupling in Individuals With Depressive Tendencies
August 07, 2026
Conditions: Depression Disorder; fMRI Research; Heart-Brain CouplingInterventions: Device: DLPFC-insula TMS; Device: DLPFC-sgACC TMS; Device: 10-20 F3 TMS; Device: sham TMS
Sponsors: Xidian University
Recruiting
Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations
August 07, 2026
Conditions: Cancer; Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma); Lung Cancer (Non-Small Cell); Liver Cancer, Adult; Cancer SurvivorInterventions: Other: structured exercise training
Sponsors: Kaohsiung Medical University Chung-Ho Memorial Hospital
Recruiting
GUT-FEELINGS: Using Citizen Science for Large-Scale Prebiotic Clinical Trials for Mental Health in Adults
August 07, 2026
Conditions: Sleep Disturbance; Stress; Feeling AnxiousInterventions: Other: Active Gut Feeling Product 1; Other: Active Gut Feeling Product 2; Other: Placebo Gut Feeling Control Product
Sponsors: Holobiome, Inc.; Radicle Science
Not yet recruiting
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
August 07, 2026
Conditions: Chronic Fatigue Syndrome (CFS)Interventions: Dietary Supplement: Placebo condition; Dietary Supplement: Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
Sponsors: Fred Friedberg
Recruiting
Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)
August 07, 2026
Conditions: Amyloidosis Cardiac; Stenosis Coronary; TAVI(Transcatheter Aortic Valve Implantation)Sponsors: University Hospital Tuebingen; Bayer
Recruiting
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
August 07, 2026
Conditions: Prediabetes; Brain Insulin Sensitivity; Cerebral Blood Flow; Satiety and Food Intake; Food Reward; Brain Health; Vascular Function; Obesity & OverweightInterventions: Dietary Supplement: Avocados
Sponsors: Maastricht University Medical Center; Avocado Nutrition Center
Not yet recruiting
Fresh Gas Flow and Lung Ultrasonography in Laparoscopic Cholecystectomy
August 07, 2026
Conditions: Postoperative Atelectasis; Pulmonary AtelectasisInterventions: Procedure: Low Fresh Gas Flow (0.5 L/min); Procedure: High Fresh Gas Flow (4 L/min)
Sponsors: Adiyaman University
Not yet recruiting
Nonintubated Anesthesia for Adult Cardiac Surgery With Cardiopulmonary Bypass
August 07, 2026
Conditions: Valve Disease, Heart; CABGInterventions: Procedure: Nonintubated Anesthesia Group; Procedure: Conventional Anesthesia Group
Sponsors: The First Affiliated Hospital of Guangzhou Medical University
Recruiting
A Trial of CRD-4730 in HFrEF
August 06, 2026
Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)Interventions: Drug: CRD-4730; Drug: Placebo
Sponsors: Cardurion Pharmaceuticals, Inc.
Recruiting
Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients
August 06, 2026
Conditions: ST-elevation Myocardial Infarction (STEMI); Acute Myocardial Infarction (AMI); Coronary Artery DiseaseInterventions: Drug: empagliflozin; Drug: Placebo
Sponsors: Rehman Medical Institute - RMI; Michigan State University
Not yet recruiting
Impact of Stroke Unit Care on Acute Stroke Outcomes
August 06, 2026
Conditions: Acute Stroke; Ischemic Stroke; Hemorrhagic StrokeSponsors: Assiut University
Not yet recruiting
Mobile Health Intervention to Increase Activity in Heart Failure Study
August 06, 2026
Conditions: Heart FailureInterventions: Behavioral: Mobile application intervention
Sponsors: University of Michigan; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.
August 06, 2026
Conditions: ASD; Scoliosis Idiopathic Adolescent; Scoliosis Idiopathic Adolescent TreatmentInterventions: Procedure: first corrective surgery; Procedure: Reoperation
Sponsors: Universitaire Ziekenhuizen KU Leuven
Recruiting
Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy
August 06, 2026
Conditions: Adverse Respiratory Events; Hypoxemia; Children; Gastroscopy; Esketamine; RemimazolamInterventions: Drug: Fentanyl and Propofol; Drug: Esketamine and remimazolam
Sponsors: Second Affiliated Hospital of Wenzhou Medical University
Not yet recruiting
One-year Clinical Outcomes of Endoscopic Cardia Banding Plication for Refractory Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
August 06, 2026
Conditions: Gastroesophageal Reflux Disease (GERD)Interventions: Procedure: endoscopic cardia banding plication
Sponsors: China-Japan Friendship Hospital
Completed
Study on Risk Factors and Prognostic Value of Non-target Lesion Progression in Patients With Coronary Artery Disease
August 06, 2026
Conditions: Coronary Artery Disease (CAD)Interventions: Other: Progression of non-target vessels
Sponsors: Beijing Anzhen Hospital
Active, not recruiting
RESTORE-ZG: Return of Effective Spontaneous Circulation Resuscitation Evaluation Canton of Zug
August 06, 2026
Conditions: Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation; Out of Hospital Cardiac Arrest; Out of Hospital Setting; Defibrillation; Resuscitation; Resuscitation RegistryInterventions: Other: Prehospital resuscitation care
Sponsors: Felix Brinkmann; Emergency Medical Service of the Canton of Zug
Completed
Exercise and Diet Responses in Adult Men With Obesity by MC4R Genotype and Metabolic Health
August 06, 2026
Conditions: Obesity; Metabolically Healthy Obesity; Metabolically Unhealthy ObesityInterventions: Behavioral: Supervised Aerobic and Resistance Exercise
Sponsors: Harbin Sport University
Completed
sirA-CPB Strategy Reduces New Ischemic/Embolic Lesions After Acute Type A Aortic Dissection Surgery
August 06, 2026
Conditions: Dissection, AorticInterventions: Behavioral: sirA-CPB strategy; Behavioral: the traditional CPB strategy
Sponsors: Xiangya Hospital of Central South University
Not yet recruiting
Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based Anesthesia
August 06, 2026
Conditions: Cardiac Disease Minimally Invasive Cardiac Surgery Postoperative PainInterventions: Drug: Dexmedetomidine; Procedure: Ultrasound-Guided Bilateral Erector Spinae Plane Block (ESPB); Drug: Fentanyl
Sponsors: Assiut University
Not yet recruiting
Use of Hydrogen Sulphide Donor (N-acetyl Cysteine) in Cases With Acute Ischemic Stroke
August 06, 2026
Conditions: Ischemic Cerebral InfarctionInterventions: Drug: N Acetyl cysteine 600mg; Drug: Normal (0.9%) saline
Sponsors: Helwan University
Completed
A Photoplethysmography-Based Machine Learning Algorithm for Early Atrial Fibrillation Detection: A Prospective Validation Study
August 06, 2026
Conditions: Atrial Fibrillation (AF); Heart FailureInterventions: Other: PPG-based AF detection algorithm
Sponsors: Seerlinq s. r. o.; ACADEMY - občianske združenie; Premedix Academy
Recruiting
Perioperative Transcutaneous Fluorescence Detection of GFR Trajectory for the Early Prediction and Diagnosis of CSA-AKI.
August 06, 2026
Conditions: Acute Kidney InjurySponsors: China National Center for Cardiovascular Diseases
Recruiting
Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities
August 06, 2026
Conditions: Cardiovascular; Comorbidity; Diabetes; Inflammatory Joint Diseases; Chronic Kidney Diease; Chronic Obstructive Pulmonary Disease (COPD); Cardiovascular DiseaseSponsors: University of Alabama at Birmingham; National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting
The Effect of Virtual Reality Glasses and Breathing Exercise on Anxiety
August 06, 2026
Conditions: Breast CancerInterventions: Behavioral: Breathing exercise; Behavioral: Virtual Reality Glasses
Sponsors: Ankara Medipol University
Completed
Effectiveness of a Low-Calorie Diet Combined With Intensive Lifestyle Intervention Using Integrated Personalized Diabetes Management for Achieving Diabetes Remission in Patients With Type 2 Diabetes Mellitus
August 06, 2026
Conditions: Type 2 Diabetes; Obesity & Overweight; Remission; Lifestyle InterventionInterventions: Behavioral: Low-calorie diet; Device: Continous Glucose Monitor (CGM); Other: Standard Care (in control arm); Behavioral: Personalized exercise program
Sponsors: Chulalongkorn University; Ratchadapiseksompotch Fund; The Royal College of Physicians of Thailand
Recruiting
Fully Remote, Telehealth-based Ketogenic Metabolic Therapy for Long COVID
August 06, 2026
Conditions: Long COVID FatigueInterventions: Other: Ketogenic Metabolic Therapy; Behavioral: Lifestyle Intervention
Sponsors: National University of Natural Medicine
Completed
Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery
August 05, 2026
Conditions: General Anesthesia; Aged; Intraoperative Hypotension; AnxietySponsors: Second Affiliated Hospital, Zhejiang University, School of Medicine
Recruiting
School-based Myopia Prevention Trial for Children With Insufficient Hyperopic Reserve
August 05, 2026
Conditions: Refractive Errors; Hyperopia; MyopiaInterventions: Other: Auricular Acupressure; Behavioral: Eye Health Education
Sponsors: Shanghai Eye Disease Prevention and Treatment Center
Recruiting
Terlipressin vs Placebo to Reduce Bleeding in Fibroid Surgery
August 05, 2026
Conditions: Uterine Fibroids (Leiomyoma); Uterine Myoma; LeiomyomaInterventions: Drug: terlipressin (vasoconstrictor); Drug: Placebo
Sponsors: Sevil Cankaya
Not yet recruiting
Snoezelen Therapy in Adults With Alcohol Dependence and Adults With Schizophrenia
August 05, 2026
Conditions: SCHIZOPHRENIA 1 (Disorder); Alcohol Use Disorder; Alcohol Dependence (Primary Condition)Interventions: Other: Snoezelen® therapy for 6 weeks; Other: Snoezelen® therapy for 12 weeks
Sponsors: The Jerzy Kukuczka Academy of Physical Education in Katowice; Clinical Psychiatric Hospital SPZOZ in Rybnik, Poland
Not yet recruiting
AI-DBT For Serious Illness
August 05, 2026
Conditions: Serious Illness; Distress, Emotional; DistressInterventions: Behavioral: AI DBT
Sponsors: Rutgers, The State University of New Jersey; University of Colorado Denver - Anschutz Medical Campus (UCD-AMC)
Not yet recruiting
Population Pharmacokinetics of Apixaban in Asian Patients With Atrial Fibrillation
August 05, 2026
Conditions: Non Valvular Atrial Fibrillation (nv AF)Interventions: Drug: Apixaban
Sponsors: Chulalongkorn University; Thammasat University; King Chulalongkorn Memorial Hospital
Not yet recruiting
Effect of a Structured Nursing Intervention Incorporating Sleep Hygiene and Cognitive-Behavioral Strategies on Sleep Quality Among Patients With Chronic Heart Failure
August 05, 2026
Conditions: Chronic Heart Failure (CHF)Interventions: Behavioral: Structured Nursing Intervention Incorporating Sleep Hygiene and Cognitive-Behavioral Strategies
Sponsors: Al-Zaytoonah University of Jordan
Completed
School-based Myopia Control Trial for Children With Premyopia or Myopia
August 05, 2026
Conditions: Myopia; Refractive ErrorsInterventions: Device: Defocus Spectacle Lenses; Other: Auricular Acupressure
Sponsors: Shanghai Eye Disease Prevention and Treatment Center
Recruiting
A Study to Evaluate the Efficacy and Safety of LZM012 ( Psoriasis )
August 05, 2026
Conditions: PsoriasisInterventions: Biological: LZM012
Sponsors: Livzon Pharmaceutical Group Inc.
Completed
A Clinical Trial of Antiplatelets in Psoriasis
August 05, 2026
Conditions: Psoriasis (PsO); Psoriatic Arthritis (PsA)Interventions: Drug: Aspirin; Drug: Clopidogrel; Other: Placebo
Sponsors: NYU Langone Health; National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting
Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients
August 05, 2026
Conditions: Frailty; Coronary Artery Disease; Coronary Artery Bypass Graft (CABG)Interventions: Procedure: Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG); Procedure: Conventional Coronary Artery Bypass Grafting (Median Sternotomy)
Sponsors: University of Sao Paulo General Hospital; Instituto Nacional de Cardiologia de Laranjeiras; Hospital e Maternidade Angelina Caron - SC; Santa Casa de Misericórdia de Maceió; Sancta Maggiore Itaim Hospital; Hospital Sao Vicente de Paulo e Hospital de Cidade, Passo Fundo, Brasil; Hospital Clínica Kennedy; Hospital Alberto Urquiza Wanderley
Not yet recruiting
Live Long, Heart Strong: A Digital Nutrition Intervention for Emerging Adults
August 05, 2026
Conditions: Eating Behavior ChangesInterventions: Behavioral: Live Long, Heart Strong (LLHS) Digital Nutrition Intervention; Behavioral: Static Digital Nutrition Education Toolkit
Sponsors: Texas A&M University
Not yet recruiting
Effect of Aerobic and Resistance Exercise on Quarry Workers
August 05, 2026
Conditions: Ventilatory Defect; Occupational Lung Diseases; Respiratory DisordersInterventions: Procedure: Aerobic exercise training; Procedure: Resistance exercise training
Sponsors: Cairo University
Recruiting
Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department
August 05, 2026
Conditions: Fever; Triage; Pediatric Emergency Medicine; Serious Bacterial Infection; SepsisInterventions: Diagnostic Test: Ministry of Health three-level color-coded triage
Sponsors: TC Erciyes University; Kayseri City Hospital; Adana City Training and Research Hospital; Cukurova University; Akdeniz University; Manisa Celal Bayar University; Eskisehir Osmangazi University; Lütfi Kırdar City Hospital; Dokuz Eylul University; Tokat Gaziosmanpasa University
Recruiting
Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy
August 04, 2026
Conditions: Bronchoscopy; Procedural SedationInterventions: Drug: Ciprofol; Drug: Propofol; Drug: Sufentanil
Sponsors: Wenzhou Central Hospital
Completed
VWCR to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study)
August 04, 2026
Conditions: Heart DiseasesInterventions: Other: Virtual Cardiac Rehabilitation; Other: In-Person Cardiac Rehabilitation
Sponsors: Mayo Clinic; National Library of Medicine (NLM)
Not yet recruiting
Selinexor, Daratumumab, and Dexamethasone (XDd) for Light-Chain Cardiac Amyloidosis
August 04, 2026
Conditions: Light-chain Cardiac AmyloidosisInterventions: Drug: XDd
Sponsors: Beijing Anzhen Hospital
Not yet recruiting
Preoperative Anxiety and Depression Among Older Chinese Patients
August 04, 2026
Conditions: Depression; Anxiety; Elderly Patients; Non-cardiac Major SurgerySponsors: Chinese PLA General Hospital; Beijing Tiantan Hospital; Peking University First Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School; Xiangya Hospital of Central South University; Beijing Anzhen Hospital; Central South University; Peking University People's Hospital; Zhejiang University; Fudan University; Sun Yat-sen University; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; China-Japan Friendship Hospital; The Affiliated Hospital Of Guizhou Medical University; First Affiliated Hospital of Xinjiang Medical University; First Affiliated Hospital of Guangxi Medical University; Taihe Hospital; Zhejiang Provincial People's Hospital; Shanghai Zhongshan Hospital
Not yet recruiting
Ablation With Transcatheter Edge-to-edge Repair for Atrial Functional Mitral Regurgitation and Atrial Fibrillation
August 04, 2026
Conditions: Atrial Functional Mitral Regurgitation; Atrial Fibrillation (AF)Interventions: Device: Transcatheter edge to edge repair; Procedure: Catheter ablation
Sponsors: Mao Chen; Abbott
Not yet recruiting
Comparing Suture vs. Combined Closure Strategies for Large Blood Vessel Access in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)
August 04, 2026
Conditions: Aortic Valve Stenosis; Postoperative Complications; Vascular System Injuries; HemorrhageInterventions: Device: Single Suture-Based Vascular Closure Device; Device: Extravascular Collagen Plug-Based Closure Device
Sponsors: University Hospital, Basel, Switzerland; University Hospital, Zürich; University Heart Center Freiburg - Bad Krozingen; University Hospital Giessen and Marburg; University Hospital Galway
Not yet recruiting
Efficacy and Accuracy of an AI-Driven Sleep Earbud for Chronic Insomnia
August 04, 2026
Conditions: Insomnia; Insomnia Chronic; Insomnia Disorders; Sleep Wake DisordersInterventions: Device: AI-driven Neuromodulation Music (NeuroRhythm); Device: Standard Music (Sham Control)
Sponsors: The Chinese University of Hong Kong, Shenzhen; Chinese University of Hong Kong
Active, not recruiting
A Prospective, Multicenter, Two-cohorts, Single Arm Study Evaluating Safety, Effectiveness and Performance of Angimis Atherectomy System for the Treatment of Non-crossable and/or Non-dilatablE Lesions in CorONary Arteries Disease (NEON Study).
August 04, 2026
Conditions: Angimis Atherectomy System is Indicated for CTO, Balloon Failure and ISR in Coronary Arteries DiseaseInterventions: Device: Adult patient population who have been diagnosed with coronary artery disease with non-crossable and/or non-dilatable lesion which requiring the treatment of PCI
Sponsors: Shenzhen Tonglu Technology Co., Ltd; Ospedale San'Anna; University of Rome Tor Vergata; Siloam Hospitals Lippo Village
Not yet recruiting
A Phase II Study of TollB-001 Tablets in Systemic Sclerosis
August 04, 2026
Conditions: Systemic Sclerosis (SSc)Interventions: Drug: TollB-001 Tablet; Drug: Placebo
Sponsors: Toll Biotech Co. Ltd. (Beijing)
Not yet recruiting
Redo-Pulmonary Vein Isolation With Versus Without Posterior Wall Ablation - The REDO-PIFPAF-PFA Study
August 04, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Procedure: Pulmonary vein isolation with posterior wall ablation; Procedure: Pulmonary vein isolation without posterior wall ablation
Sponsors: University Hospital, Basel, Switzerland; Swiss Heart Foundation; Boston Scientific Corporation
Not yet recruiting
The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Retrospective Multicenter Observational Study
August 04, 2026
Conditions: Cohort StudiesSponsors: Chinese PLA General Hospital; Beijing Tsinghua Changgeng Hospital; Peking University First Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School; Xiangya Hospital of Central South University; Beijing Anzhen Hospital; Central South University; Peking University People's Hospital; Zhejiang University; Fudan University; Sun Yat-sen University; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; China-Japan Friendship Hospital; The Affiliated Hospital Of Guizhou Medical University; First Affiliated Hospital of Xinjiang Medical University; First Affiliated Hospital of Guangxi Medical University; Taihe Hospital
Not yet recruiting
Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease
August 04, 2026
Conditions: Hemodialysis; Ischemia Preconditioning; Chronic Kidney Disease; Blood Pressure Disorders; InflammationInterventions: Other: Preconditioning with control ischemic episodes
Sponsors: Medical University of Lodz
Recruiting
Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer
August 04, 2026
Conditions: Breast Cancer Stage I; Colorectal CancerInterventions: Other: Media Intervention; Other: Media Intervention; Procedure: Mind-body intervention; Procedure: Meditation Therapy
Sponsors: Roswell Park Cancer Institute
Not yet recruiting
Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS)
August 04, 2026
Conditions: StillbirthSponsors: RTI International; Old Dominion University; University of Utah; Columbia University; University of California, San Diego; Oregon Health and Science University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting
The Effect of Combined Brain Stimulation and Exercise for Improving Cognitive Function in Schizophrenia
August 04, 2026
Conditions: Schizophrenia; Cognitive FunctionsInterventions: Behavioral: Aerobic exercise; Device: Active tDCS; Device: Sham tDCS
Sponsors: The Hong Kong Polytechnic University
Not yet recruiting
Relationship Between Frontal QRS-T Angle and Collateral Circulation in Coronary Artery Chronic Total Occlusion
August 04, 2026
Conditions: Chronic Total Occlusion (CTO); Frontal QRS-T AngleInterventions: Diagnostic Test: 12-lead Electrocardiogram (ECG) and Coronary Angiography
Sponsors: Assiut University
Not yet recruiting
Does Use of a Pre-Procedure Educational Video for Urodynamic Testing Reduces Anxiety?
August 04, 2026
Conditions: Urinary Incontinence; Urinary Bladder Overactive; Urinary Incontinence , StressInterventions: Other: video
Sponsors: Yair Daykan
Recruiting
Niaoduqing Granules in Older Adults With Impaired Kidney Function
August 03, 2026
Conditions: Chronic Kidney DiseaseInterventions: Drug: Intervention Name
Sponsors: Huashan Hospital
Recruiting
ReSeT in ALL 2: A Randomized, Controlled Pilot Trial Testing an Optimized, Multi-component Mobile Health Intervention to Reduce Sedentary Time in Early Adolescents and Young Adults (eAYAs) With ALL During Maintenance Therapy
August 03, 2026
Conditions: Acute Lymphoblastic Leukemia (ALL); Sedentary Behavior / Physical Inactivity; Cardiometabolic HealthInterventions: Behavioral: ReSeT2 Intervention
Sponsors: Children's Hospital Los Angeles
Not yet recruiting
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
August 03, 2026
Conditions: Non-communicable Diseases (NCD); Neoplams; Cancer; Lung Cancer (NSCLC); Cardiovascular Diseases (CVD); Atherosclerotic Cardiovascular Disease (ASCVD); Peripheral Artery Disease (PAD); Coronary Artery Disease (CAD); Stroke (CVA) or TIA; Diabetes Mellitus (DM); Type 2 Diabetes (T2DM); Prediabetes; Chronic Respiratory Diseases; Chronic Obstructive Pulmonary Disease (COPD)Sponsors: Center for Molecular Fingerprinting Research Nonprofit LLC; Szeged University; Ludwig-Maximilians - University of Munich; Max Planck Institute of Biochemistry; Technical University of Munich; Helmholtz Zentrum München
Recruiting
A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs)
August 03, 2026
Conditions: Triple Negative Breast Cancer (TNBC); Elevated Tumor-Infiltrating LymphocytesInterventions: Drug: Carboplatin; Drug: Paclitaxcel; Drug: Pembrolizumab
Sponsors: Medical University of South Carolina; State University of New York - Upstate Medical University
Not yet recruiting
ThromBus Aspiration for Acute Mesenteric Artery Occlusion With Emergent Laparoscopic Surgery
August 03, 2026
Conditions: Acute Mesenteric IschemiaInterventions: Procedure: thrombus aspiration-based endovascular therapy
Sponsors: Beijing Tsinghua Chang Gung Hospital; West China Hospital; The First Affiliated Hospital of Anhui Medical University; Tianjin Nankai Hospital; The Second Affiliated Hospital of Harbin Medical University; Loudi Central Hospital
Active, not recruiting
Clinical Validation of Vital-PICASO for Predicting Cardiac Arrest Within 24 Hours
August 03, 2026
Conditions: Heart ArrestSponsors: Huinno AIM
Completed
The Effect of an Intervention Based on The CSM on Self-Management in Patients After Atrial Fibrillation Ablation
August 03, 2026
Conditions: Atrial FibrillationInterventions: Behavioral: Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Intervention Group; Behavioral: Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Control Group
Sponsors: Binzhou People's Hospital; Qingdao University
Completed
The Cardiovascular Effects of Patent Foramen Ovale in Hypoxia
August 03, 2026
Conditions: Patent Foramen Ovale (PFO); High Altitude Pulmonary EdemaSponsors: University of Texas Southwestern Medical Center
Not yet recruiting
Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine
August 03, 2026
Conditions: Migraine DisordersInterventions: Drug: Melatonin; Drug: Propranolol
Sponsors: Nishtar Medical University
Enrolling by invitation
Comparison of Erector Spinae Plane Block and Modified Pectoral Fascial Plane Block for Postoperative Analgesia in Pediatric Cardiac Surgery
August 03, 2026
Conditions: Congenital Heart Disease; Postoperative Pain After Cardiac Surgery Via Median Sternotomy; AnesthesiaInterventions: Procedure: Ultrasound-Guided Erector Spinae Plane Block; Procedure: Ultrasound-Guided Modified Pectoral Fascial Plane Block
Sponsors: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Enrolling by invitation
Empowering Veterans in Research Effectively Using Virtual Engagement Tools
August 03, 2026
Conditions: Atrial Fibrillation (AF); Cardiovascular DiseasesInterventions: Behavioral: AI-Generated Avatar Videos and Chatbot for Clinical Trial Outreach
Sponsors: Stanford University; Palo Alto Veterans Institute for Research; VA Palo Alto Health Care System
Not yet recruiting
Prediction Model of Spontaneous Closure of Congenital Perimembranous Ventricular Septal Defects
August 03, 2026
Conditions: Ventricular Septal DefectsSponsors: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Withdrawn
My Hospital Buddy Ida: AR-CBT for Children With Cancer
August 03, 2026
Conditions: Pediatric Cancer; Cancer-Related Distress; Quality of Life; AnxietyInterventions: Behavioral: Augmented Reality-Supported CBT ("My Hospital Buddy Ida"); Behavioral: Standard CBT (Printed Workbook)
Sponsors: Koç University; Akdeniz University; Health Institutes of Türkiye (TÜSEB)
Completed
Primary Palliative Care - a Feasibility Cluster Trial
August 03, 2026
Conditions: Palliative Care; Primary Palliative Care; Advanced Cancer; Chronic Obstructive Pulmonary Disease (COPD); Congestive Heart Failure Chronic; Chronic Kidney Disease (Stages 4 and 5)Interventions: Other: Primary Palliative Care Complex Intervention (PrimPal)
Sponsors: University of Coimbra; Unidade Local de Saúde de Coimbra, EPE
Not yet recruiting
Neurocognitive Effects of Extended-Release Methylphenidate in Healthy Adults
August 03, 2026
Conditions: Healthy Adult Male and Female VolunteersInterventions: Drug: Methylphenidate Stimulant medication therapy; Other: Placebo Capsule(s)
Sponsors: University of Witwatersrand, South Africa
Completed
Oxytocin in Postmenopausal Women
August 03, 2026
Conditions: Postmenopausal; PremenopausalInterventions: Other: Repeated assessments
Sponsors: University Hospital, Basel, Switzerland
Not yet recruiting
Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy
August 03, 2026
Conditions: Fiberoptic Bronchoscopy (FOB); Lung Cancer (Diagnosis); PremedicationInterventions: Drug: Nebulized lidocaine and ketamine; Drug: Nebulized Lidocaine; Drug: Lidocaine spray (2%)
Sponsors: Alexandria University
Completed
Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With Reduced and Mildly Reduced Ejection Fraction.
August 03, 2026
Conditions: Heart FailureSponsors: Istituti Clinici Scientifici Maugeri SpA
Recruiting
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
August 03, 2026
Conditions: Pulmonary Hypertension; Right Ventricular Outflow Tract Dysfunction; Fontan CirculationInterventions: Diagnostic Test: Right-left heart catheterization in magnetic resonance imaging (MRI)
Sponsors: Tobias Rutz
Enrolling by invitation
A Study on the Efficacy and Safety of Anrikefon for Postoperative Pain Relief Following Laparoscopic Cholecystectomy
August 03, 2026
Conditions: Gallbladder Stones; Gallbladder PolypsInterventions: Drug: Anrikefon; Drug: Dezocine
Sponsors: Affiliated Hospital of Guangdong Medical University
Not yet recruiting
PRECISE-AFMR I: Transcatheter Mitral Valve Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation in Patients at High Surgical Risk
August 03, 2026
Conditions: Atrial Functional; Mitral Regurgitation (MR)Interventions: Device: Transcatheter Edge-to-Edge Repair
Sponsors: China National Center for Cardiovascular Diseases; Chinese Academy of Medical Sciences, Fuwai Hospital
Not yet recruiting
Clinical Study of Coronary Extension Catheter
August 03, 2026
Conditions: Coronary Artery Disease (CAD); Percutaneous Coronary Intervention (PCI)Interventions: Device: Coronary Extension Catheter
Sponsors: BrosMed Medical Co., Ltd
Recruiting
Study on the Effect of Famotidine on Pharmacokinetics of Taletrectinib
August 03, 2026
Conditions: Healthy Adult ParticipantsInterventions: Drug: Taletrectinib; Drug: Taletrectinib, Famotidine; Drug: Taletrectinib, Famotidine; Drug: Taletrectinib; Drug: Taletrectinib, Famotidine; Drug: Taletrectinib,Famotidine
Sponsors: Nuvation Bio Inc.
Not yet recruiting
Clinical Validation of Vital-PICASO for Predicting Hypotension Within 24 Hours in General Ward Inpatients
August 03, 2026
Conditions: HypotensionSponsors: Huinno AIM
Completed
Study on the Rapid Diagnostic Value of Sudden Clap Provocation Test in Psychogenic Nonepileptic Seizures
August 03, 2026
Conditions: Epilepsy; Psychogenic Non-epileptic SeizuresInterventions: Diagnostic Test: Abrupt Clap Provocation Test
Sponsors: Xijing Hospital
Active, not recruiting
Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity
August 03, 2026
Conditions: Heart Failure and Reduced Ejection Fraction; Obesity & Overweight; TirzepatideInterventions: Drug: Tirzepatide; Drug: Placebo
Sponsors: Shahid Beheshti University of Medical Sciences; Cinnagen
Not yet recruiting
Optimal Timing of Staged Complete Revascularization in STEMI With Multivessel Disease
August 03, 2026
Conditions: Myocardial Infarction (MI)Interventions: Procedure: In-hospital staged complete revascularization; Procedure: Out-of-hospital staged complete revascularization
Sponsors: Chonnam National University Hospital
Not yet recruiting
Patient-Executed, Clinician-Confirmed Diuretic Titration in Pulmonary Artery Pressure-Guided Heart Failure (SURPASS-HF)
August 03, 2026
Conditions: Heart FailureInterventions: Other: Shared-management diuretic titration guided by remote PA pressure monitoring
Sponsors: Medical College of Wisconsin
Completed
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
August 03, 2026
Conditions: Acute Myocardial Infarction (AMI); Percutaneous Coronary Intervention (PCI); Coronary Artery Bypass Graft Surgery (CABG); Chronic Heart Failure With Reduced Ejection Fraction (HFrEF); Heart Valve Repair or Replacement; Stable Angina PectorisInterventions: Other: CBCR; Behavioral: BRIDGE mHealth intervention
Sponsors: University of Illinois at Chicago; National Center for Advancing Translational Sciences (NCATS)
Not yet recruiting
Association of Lipoprotein(a) With Postoperative Atrial Fibrillation
August 03, 2026
Conditions: POAF; Atrial Fibrillation (AF)Sponsors: Anthony Tang
Not yet recruiting
aDAPt-ANOCA: Dapagliflozin for the Treatment of Angina With Non-Obstructive Coronary Artery Disease (ANOCA)
August 03, 2026
Conditions: Angina With Non-Obstructive Coronary Artery Disease; Coronary Microvascular Dysfunction (CMD)Interventions: Drug: Dapagliflozin (10mg Tab); Drug: Placebo ( FE)
Sponsors: The Christ Hospital
Not yet recruiting
Diagnostic Accuracy of a Deep Learning-Based Software for Automated Multiparametric Echocardiographic Measurements
July 31, 2026
Conditions: Echocardiography; Artificial Intelligence; Diagnostic ImagingSponsors: Centro Cardiologico Monzino; Azienda Ospedaliero Universitaria Policlinico Modena; Universita di Verona; Monaldi Hospital, Napoli, Italy; ASST Grande Ospedale Metropolitano Niguarda; Azienda Ospedaliera Universitaria Policlinico "G. Martino"; Ospedale San Giovanni Evangelista Tivoli
Recruiting
Systematic Ambulatory ECG Monitoring Following TAVI
July 31, 2026
Conditions: Aortic Stenosis; Conduction DisturbancesInterventions: Device: Ambulatory ECG monitoring
Sponsors: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Not yet recruiting
Routine LDL Exam For Cancer Survivors
July 31, 2026
Conditions: Cancer Survivorship; Cardiovascular DiseaseSponsors: Samsung Medical Center; Institution of cancer quality of life, Samsung Medical Center
Completed
Tirzepatide Impact Assessment Study
July 31, 2026
Conditions: Obesity & Overweight; Cardiometabolic Health Indicators; Addiction; Eating Disorders; Mental HealthInterventions: Drug: GLP-1 Receptor Agonist Therapy; Behavioral: Structured Lifestyle Intervention
Sponsors: Texas Tech University
Recruiting
Effects of Exercise Intervention on Sleep Quality and Emotional Problems in College Students With Depressive Symptoms
July 31, 2026
Conditions: Depressive Symptoms; Sleep DisturbanceInterventions: Behavioral: Archery Exercise; Behavioral: Non-exercise Control
Sponsors: Capital University of Physical Education and Sports, China
Not yet recruiting
Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management
July 31, 2026
Conditions: Coronary Artery Disease; Atrial Fibrillation (AF); Heart Failure; StrokeInterventions: Device: Medical large language model
Sponsors: Jiangsu Taizhou People's Hospital
Not yet recruiting
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care
July 31, 2026
Conditions: Retinopathy of Prematurity (ROP)Interventions: Device: Ultra-widefield Optical Coherence Tomography (UWF-OCT); Device: Wide-field ophthalmic imaging system
Sponsors: Duke University; University of Pennsylvania; National Eye Institute (NEI)
Not yet recruiting
Effects of Cornelian Cherry Supplementation in Patients With Metabolic Syndrome
July 31, 2026
Conditions: Metabolic SyndromeInterventions: Dietary Supplement: Placebo; Dietary Supplement: Cornus mas Fruit Lyophilizate
Sponsors: Wroclaw Medical University
Completed
Impact of Preferred Music on Laparoscopic Task Performance and Mental Workload in Novice Surgeons
July 31, 2026
Conditions: Laparoscopic Surgery Simulation; Mental Workload; Stress; Psychomotor PerformanceInterventions: Behavioral: Behavioral: Preferred Music; Behavioral: White Noise; Behavioral: SIlent Control
Sponsors: Hospital Universiti Sains Malaysia
Completed
Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass Surgery
July 31, 2026
Conditions: Coronary Artery Disease; Perioperative BleedingInterventions: Drug: Oral tranexamic acid; Drug: Exacyl®; Drug: Intravenous placebo
Sponsors: Clinique Saint-Luc
Not yet recruiting
Factors Affecting Clinical and Radiological Outcome in Endovascular Management of Acute Ischemic Stroke Due to Large Vessel Occlusion
July 31, 2026
Conditions: Endovascular ThrombectomyInterventions: Procedure: endovascular thrombectomy
Sponsors: Sohag University
Recruiting
Study to Evaluate the effIcacy and Safety of Abelacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral Anticoagulation
July 31, 2026
Conditions: Atrial Fibrillation (AF)Interventions: Biological: Abelacimab
Sponsors: Novartis Pharmaceuticals
Not yet recruiting
NAD Supplementation to Reduce the Incidence of Cardiac Surgery Associated Acute Kidney Injury
July 31, 2026
Conditions: Acute Kidney InjuryInterventions: Dietary Supplement: Nicotinamide (NAM); Dietary Supplement: Placebo control
Sponsors: Beth Israel Deaconess Medical Center
Not yet recruiting
Same-Day Versus Standard Hospital Discharge After TAVI (HOME-TAVI)
July 31, 2026
Conditions: Aortic Stenosis, Severe; Aortic StenosisInterventions: Other: Same-Day Discharge Strategy; Other: Standard-of-Care Discharge Strategy
Sponsors: Hospital Clinic of Barcelona
Not yet recruiting
Multimodal Tracking of Therapy Activity and Effort During Rehabilitation
July 31, 2026
Conditions: Stroke; Cerebral Palsy; Spinal Cord Injury; Parkinsons; ALSSponsors: ETH Zurich
Active, not recruiting
A Prospective, Multicenter, Phase III Clinical Evaluation of the Safety and Efficacy of NH002 as a Contrast Agent Administrated Via Intravenous Bolus Injection and Infusion for Subjects Undergoing Cardiac Echocardiography
July 31, 2026
Conditions: Cardiac DiseasesInterventions: Drug: NH002 (Perflutren Lipid Microspheres) Injectable Suspension
Sponsors: Trust Bio-sonics, Inc.; Syneos Health
Not yet recruiting
Body-Based and Mind-Based Regulation in Overweight and Obese Women
July 31, 2026
Conditions: Overweight and/or ObesityInterventions: Behavioral: Body-Based Regulation Program; Behavioral: Mind-Based Regulation Program
Sponsors: Pamukkale University
Not yet recruiting
Terbinafine for CSA-AKI Prevention
July 31, 2026
Conditions: Acute Kidney Injury; Cardiac Surgical ProceduresInterventions: Drug: Terbinafine
Sponsors: Guangdong Provincial People's Hospital
Not yet recruiting
ATR 1072 in Participants With PRKAG2 Syndrome
July 31, 2026
Conditions: Cardiac Glycogenosis; Cardiomyopathy; Hypertrophic; Wolff-Parkinson-White SyndromeInterventions: Drug: ATR 1072
Sponsors: Atrium Therapeutics
Not yet recruiting
Caffeine Consumption and Rate Control in Permanent Atrial FIBrillation: The CAFIB Trial
July 31, 2026
Conditions: Atrial Fibrillation (AF); Permanent Atrial Fibrillation; Coffee Consumption; Caffeine AbuseInterventions: Dietary Supplement: Dietary Caffeine Intake
Sponsors: Hospital Universitario Getafe; Instituto de Investigación Sanitaria Getafe
Recruiting
Virtual Reality Distraction During Restorative Dental Treatment
July 31, 2026
Conditions: Dental Anxiety; PainInterventions: Device: Virtual Reality Headset; Other: Standard Dental Treatment
Sponsors: Qassim University
Recruiting
Predication of Arterial Stiffness in Healthy Adults by Oral Health and Chewing Assessments
July 30, 2026
Conditions: Arterial Stiffness; Oral Health; Mastication; Deglutition; Vascular Aging; Cardiovascular RiskInterventions: Diagnostic Test: Dentition and Occlusal Status Assessment; Diagnostic Test: Oral Health Assessment Tool; Diagnostic Test: Maximum Bite Force Measurement; Diagnostic Test: Tongue Strength and Endurance Assessment; Diagnostic Test: Hue-Check Chewing Efficiency Test; Diagnostic Test: Test of Masticating and Swallowing Solids; Diagnostic Test: Food Avoidance Texture-Based Questionnaire; Diagnostic Test: Oral Health Impact Profile; Diagnostic Test: Masseter Muscle Thickness Measurement
Sponsors: VASCage GmbH
Recruiting
Trauma-informed Psilocybin Assisted Psychotherapy (TiPAP) for PTSD
July 30, 2026
Conditions: Post-Traumatic Stress Disorder, PTSDInterventions: Drug: Psilocybin (drug); Behavioral: Trauma-Focused Psychotherapy
Sponsors: Tel-Aviv Sourasky Medical Center; Tel Aviv University Sagol School of Neuroscience
Recruiting
The Impact of Diabetes Remission on Aging
July 30, 2026
Conditions: Type 2 DiabetesInterventions: Other: Comprehensive Lifestyle Intervention
Sponsors: Second Affiliated Hospital, Zhejiang University, School of Medicine
Not yet recruiting
Evaluate the Value of Modified Shock Index in Predicting the Incidence of Cardiovascular Events After Non-cardiac Surgery in Cardiac Patients
July 30, 2026
Conditions: Cardiovascular Diseases (CVD); PostoperativeSponsors: Fujian Medical University Union Hospital
Not yet recruiting
The Two-handed Mask Ventilation Study
July 30, 2026
Conditions: Airway Anesthesia; Ventilation, MechanicalInterventions: Procedure: V-E two handed mask ventilation technique; Procedure: C-E two handed mask ventilation technique
Sponsors: Indonesia University
Completed
Myocardial Metabolic Flux in Pulmonary Arterial Hypertension
July 30, 2026
Conditions: Pulmonary Arterial HypertensionInterventions: Drug: GLP-1 agonist
Sponsors: Imperial College London
Not yet recruiting
Aspirin-Free Strategy After 3-6 Month Dual Antiplatelet Therapy in Acute Coronary Syndrome
July 30, 2026
Conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI); Dual Anti-platelet TherapyInterventions: Drug: Aspirin-Free Strategy; Drug: Dual Antiplatelet Therapy
Sponsors: Assiut University
Not yet recruiting
Adapted Physical Activity and Tango-Based Therapy for Parkinson's Disease: A Pilot Study
July 30, 2026
Conditions: Parkinson's Disease (PD)Interventions: Other: Riabilitango® Tango-based program; Other: Motor Reconditioning
Sponsors: University of Foggia
Completed
Remote ECG Monitoring-Based Phase I Cardiac Rehabilitation After Heart Surgery
July 30, 2026
Conditions: Heart Disease; Cardiac Surgery; Cardiac RehabilitationInterventions: Device: MEMO Patch; Behavioral: Phase I Cardiac Rehabilitation Program
Sponsors: HUINNO Co., Ltd
Completed
Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters
July 30, 2026
Conditions: Athletic Performance EnhancementInterventions: Behavioral: Blood Flow Restriction Roller Skating Training; Behavioral: Standardized Roller Skating Training
Sponsors: Shanghai University of Sport
Not yet recruiting
Examining Relationships Between Musculoskeletal Function Measurements of Movement Efficiency and Nervous System Function After Chronic Stroke
July 30, 2026
Conditions: Stroke; Osteopathic Medicine; Physical Examination; Heart Rate Variability (HRV); Energy Expenditure; Patient Reported Outcome (PRO)Sponsors: University of California, Davis
Recruiting
Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome
July 30, 2026
Conditions: Acute Myeloid Leukemia; Myelodysplastic SyndromeInterventions: Procedure: Allogeneic Hematopoietic Stem Cell Transplantation; Drug: Arsenic Trioxide; Procedure: Biospecimen Collection; Procedure: Bone Marrow Biopsy; Drug: Busulfan; Drug: Fludarabine
Sponsors: University of Michigan Rogel Cancer Center
Not yet recruiting
Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors With Statin for ACS Patients
July 30, 2026
Conditions: Acute Coronary SyndromesInterventions: Drug: PCSK9 inhibitor plus rosuvastatin 20 mg tab; Drug: Rosuvastatin 20 Mg Oral Tablet
Sponsors: Assiut University
Not yet recruiting
Alleviation of Hypercholesterolemia Through Newly Developed Cookies Supplementedwithpumpkin (Cucurbita Pepo L.) Seeds and Walnuts (Juglans Regia L.) Among Arthrosclerosispatients.
July 30, 2026
Conditions: Hypercholesterolemia; ArthrosclerosisInterventions: Dietary Supplement: Pumpkin Seed and Walnut Cookies; Other: Standard Care (Control)
Sponsors: Kamran Hanif; University of Lahore
Completed
A Study of Radical Cystectomy in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) and Muscle Invasive Bladder Cancer (MIBC) in Korea
July 30, 2026
Conditions: Urinary Bladder NeoplasmsSponsors: Janssen Korea, Ltd., Korea
Not yet recruiting
Evaluation of a Couple-based Psycho-socio-educational Intervention Using WeChat/WhatsApp on Dyadic Psychological and Sleep Outcomes
July 30, 2026
Conditions: Sleep Problems; Psychological; Well-Being, PsychologicalInterventions: Behavioral: Couple-based psycho-socio-educational intervention using WeChat/WhatsApp
Sponsors: Chinese University of Hong Kong; Hospital Authority, Hong Kong
Not yet recruiting
Efficacy of Combined Endoscopic Third Ventriculostomy and Choroid Plexus Cauterization in Treatment of Hydrocephalus
July 30, 2026
Conditions: Paediatric HydrocephalusInterventions: Procedure: Combined endoscopic third ventriculostomy & coroid plexus cauterization
Sponsors: Assiut University
Not yet recruiting
Smartphone Application to PREDICT Real-Time Cardiovascular Risk for Heart Attack and Stroke
July 30, 2026
Conditions: Myocardial Infarction (MI); StrokeInterventions: Device: Smartphone application Antshrike
Sponsors: Stanford University; Before Health Intelligence Ltd; Samsung Electronics Co., Ltd
Not yet recruiting
Dozee Validation for Contactless Heart Rate and Respiration Monitoring in Clinical Settings
July 30, 2026
Conditions: No Specific Medical Conditions or Disease StatesInterventions: Device: Telemetry monitoring
Sponsors: Turtle Shell Technologies Pvt. Ltd.
Recruiting
Continuous Wearable Biometric Monitoring in Adults Undergoing Obesity Treatment (SMART-BMI)
July 30, 2026
Conditions: ObesityInterventions: Behavioral: Biometric-informed care; Behavioral: Control Arm: Standard Care
Sponsors: Jeff Reeves; Oura health oy
Not yet recruiting
TREPROSTINIL in Pulmonary Hypertension: Evidence and Clinical Trends
July 30, 2026
Conditions: Pulmonary Arterial Hypertension (PAH)Interventions: Drug: treprostinil
Sponsors: AOP Orphan Pharmaceuticals AG
Not yet recruiting
ACetazolamide in Patients With Heart Failure, to Decrease Weight and relIEVE Symptoms.
July 30, 2026
Conditions: Heart FailureInterventions: Drug: Acetazolamide and furosemide; Drug: Furosemide
Sponsors: University Hospital, Montpellier
Not yet recruiting
Music Therapy in Parkinson's Disease
July 30, 2026
Conditions: Parkinson's Disease (PD)Interventions: Other: Music therapy
Sponsors: Siegward -M. Elsas
Recruiting
Robotic Neurorehabilitation in Patients With Ataxia
July 29, 2026
Conditions: Ataxia - OtherInterventions: Other: Robot-Assisted Neurorehabilitation; Other: Conventional Neurorehabilitation
Sponsors: Somogy Megyei Kaposi Mór Teaching Hospital
Active, not recruiting
Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband
July 29, 2026
Conditions: Total Thyroidectomy; Hyperthyroidism; HypothyroidismInterventions: Device: Xiomi Smart Band 10
Sponsors: Yeditepe University Hospital
Recruiting
Angiotensin Receptor Blocker After TAVR in Severe Aortic Stenosis With Left Ventricular Hypertrophy (ARBITAR)
July 29, 2026
Conditions: Transcatheter Aortic Valve Replacement (TAVR); Left Ventricular Hypertrophy; Severe Aortic StenosisInterventions: Drug: Angiotensin Receptor Blocker (ARB)
Sponsors: Seoul National University Hospital; Samjin Pharmaceutical Co., Ltd.
Not yet recruiting
Spinal Versus General Anesthesia on Coagulation and Fibrinolysis During Transurethral Resection of the Prostate
July 29, 2026
Conditions: Benign Prostatic Hyperplasia; Transurethral Resection of the Prostate (TURP)Interventions: Procedure: Spinal Anesthesia (bupivacaine); Procedure: General Anaesthesia
Sponsors: Haseki Training and Research Hospital
Completed
Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy
July 29, 2026
Conditions: Cardiac Amyloidosis; Left Ventricular Hypertrophy; Conduction AbnormalityInterventions: Diagnostic Test: Cardiac amyloidosis screening during CIED implantation
Sponsors: Assistance Publique - Hôpitaux de Paris
Not yet recruiting
Rehabilitation With Wearable Monitors for Post-Lung Cancer Surgery
July 29, 2026
Conditions: Non-Small Cell Lung Cancer (NSCLC); Rehabilitation; Thoracic SurgeryInterventions: Device: Wireless Wearable Vital Sign and Activity Monitor; Behavioral: Digital Postoperative Rehabilitation Program; Other: Standard Postoperative Rehabilitation Education
Sponsors: West China Hospital
Not yet recruiting
Conduction System Pacing Display Research System for SmartSync Pacing System Analyzer
July 29, 2026
Conditions: BradycardiaInterventions: Device: CSP Display research system
Sponsors: Medtronic Cardiac Rhythm and Heart Failure
Recruiting
A Prospective, Multi-centre, Single Arm, Pivotal Clinical Study to Determine the Safety and Effectiveness of Crea Aortic Valve for Use as a Replacement Aortic Heart Valve
July 29, 2026
Conditions: Aortic Valve Stenosis; Severe Aortic StenosisInterventions: Device: Investigational Transcatheter Aortic Valve Replacement System
Sponsors: Onecrea Medical Inc.
Not yet recruiting
FlexED: Full Threshold ED Substudy
July 29, 2026
Conditions: Eating Disorders; Body ImageInterventions: Behavioral: FlexED
Sponsors: Duke University
Not yet recruiting
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition
July 29, 2026
Conditions: Menopause; Perimenopause; Vasomotor Symptoms; Cardiovascular Disease Risk Factor; Menopausal Hormone Therapy; Cardiac Remodeling; Myocardial Fibrosis; Microvascular Dysfunction; Cognitive Function AssessmentInterventions: Drug: Transdermal estradiol; Drug: Standard of care - non hormonal
Sponsors: McGill University Health Centre/Research Institute of the McGill University Health Centre
Not yet recruiting
Effects of Periodontitis on Heart Rate Variability
July 29, 2026
Conditions: Periodontitis; Cardiac ElectrophysiologyInterventions: Procedure: Non-surgical periodontal therapy
Sponsors: University of Sao Paulo
Active, not recruiting
Remimazolam-Fentanyl Mild Conscious Sedation Regimen in Pulsed-Field Ablation for Paroxysmal Atrial Fibrillation
July 29, 2026
Conditions: Atrial Fibrillation (AF)Sponsors: Charles University, Czech Republic
Recruiting
Exercise Therapy for Women With ANOCA
July 29, 2026
Conditions: Angina Patients With Non-obstructive Coronary Artery DiseaseInterventions: Behavioral: Resistance based exercise
Sponsors: NHS Greater Glasgow and Clyde; The University of Glasgow
Not yet recruiting
A Blood Pressure-Lowering Diet for Preventing and Managing Hypertension
July 29, 2026
Conditions: HypertensionInterventions: Behavioral: Standard Hypertension Management; Behavioral: Eastern Blood Pressure-Lowering Diet
Sponsors: Peking University; Shengli Oilfield Hospital
Not yet recruiting
TELEREHAB-BR: Cardiovascular Rehabilitation Models Trial
July 29, 2026
Conditions: Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)); Chronic Heart Failure; Acute Coronary Syndromes (ACS)Interventions: Behavioral: Hybrid Cardiac Telerehabilitation; Behavioral: Traditional Center-Based Cardiac Rehabilitation (TCR); Behavioral: Usual Care Group
Sponsors: University of the State of Santa Catarina; Instituto de Cardiologia de Santa Catarina
Not yet recruiting